Vol 52, No 5 (1971)
The 24th Congress of the CPSU and the next health challenges
Abstract
The 24th Congress of the Communist Party of the Soviet Union was a major event in the life of the Soviet people, an important milestone in the construction of communism. The Congress summed up the results of the past five-year plan and developed a scientifically substantiated programme for the coming years. The Congress convincingly demonstrated the world-historical significance of communist construction in the USSR and demonstrated the advantages of the Soviet state system on the irrefutable facts of the life of the Soviet people.
On carcinogenic hydrocarbons in soils of the Soviet Union
Abstract
When investigating environmental contamination by any widespread damaging agent (radioactive substances, pesticides, various other chemical compounds), researchers inevitably turn to the study of soil contamination by this agent. This was the case with carcinogenic polycyclic aromatic hydrocarbons (PAHs). Following the detection of these substances in the atmospheric air of cities, studies have been carried out aimed at their indication in soil.
On spontaneous regression of malignant tumours
Abstract
Spontaneous regression of malignant neoplasms is known in both clinical and experimental tumour pathology. However, this is not universally accepted as a possible outcome of tumour disease; furthermore, there are many well-founded statements about the improbability of such a process.
Some data on aerocarcinogens
Abstract
Vehicle exhaust gases are one of the main sources of atmospheric air pollution by products of incomplete fuel combustion. A number of studies have proved that soot and exhaust gases from internal combustion engines used in road transport contain carcinogenic substances and among them benz(a)pyrene (BP), a polycyclic hydrocarbon that is most persistent in the environment and very active in carcinogenic terms.
Some results of a study of the epidemiology of malignant lip tumours using mathematical modelling
Abstract
Modeling was carried out according to the methods developed at the Department of Malignant Tumor Epidemiology and Medical Cybernetics Laboratory of the Institute of Experimental and Clinical Oncology of the USSR Academy of Medical Sciences based on one of the principles of computer "training" for classification of complex situations proposed by the Institute of Automatics and Telemechanics of the USSR Academy of Sciences (the principle of forming a generalized class portrait, where a complex situation is a set of factors taking into account their mutual influence and interrelation chosen by a researcher to find out the role of this set in the genesis of one form of cancer (in this case of malignant lip tumors - one situation) and in norm (control group - another situation).
Bronchogenic mediastinal cysts
Abstract
Five patients aged 7, 10, 33, 50 and 53 years were treated in our department with bronchogenic cysts. In 3 patients the correct diagnosis was established before the operation, in 2 patients a mediastinal neuroma was suspected. All of them were successfully operated.
Large intestinal tumours in the clinic of acute intestinal obstruction
Abstract
The course of colorectal cancer in 25-35% of patients is complicated by acute bowel obstruction. In some institutions, 75% of colorectal cancer patients are admitted for emergency surgery due to this complication. This situation makes the issue proposed for discussion an urgent one.
On the development of hypernephroid cancer from the epithelium of the Shumlansky-Bowman capsule
Abstract
Of the 300 hypernephrotic cancer patients we observed, 5 (31 to 70 years of age) developed cancer from the epithelium of the Shumlansky-Beaumann capsule. The duration of the disease ranged from one year to 16 years. In 3 patients the tumours were diagnosed clinically and operatively removed. In 2 patients the tumour was detected accidentally in the section and was not clinically evident.
Blood examination by leucocyte concentration method in patients with acute leukaemia
Abstract
One of the modern methods that allow peripheral blood to be studied on a broad morphological scale is the leukoconcentration method. It can be used to increase the concentration of leucocytes in a preparation by a factor of 50-60 compared to the initial level, i.e. to achieve a concentration of bone marrow punctate cells. Haematologists have been using this method since the 50s to detect blood elements rarely seen in conventional tests.
About partial lung resections for cancer
Abstract
Recently, both in domestic and foreign literature there are more and more works devoted to the choice of the volume of resections in primary lung cancer. Some authors, comparing the results of operations after partial resections and pneumonectomies, come to the conclusion that lobectomy may be the operation of choice in primary lung cancer; others, having developed broader indications for lobectomies, resort to them quite often, not opposing them to pneumonectomies. The expediency of partial resections and the indications for them should be determined by studying the immediate and, mainly, long-term results of surgical treatment of primary lung cancer.
On the scope of radical operations for colorectal cancer
Abstract
Colorectal cancer has been occurring more and more frequently in recent years. From 1950 to 1964, 188 patients were operated on in our clinic with various localizations of colorectal cancer (except rectum), and 149 patients over the last six years, which indicates not only improved diagnostics and increased interest in this form of cancer from our side, but also an absolute increase in colorectal cancer.
Synchronised extirpation of a rectal cancer lesion
Abstract
In the laboratory of proctology with clinic of the RSFSR in 1960-1969, 350 single-stage combined extirpations of rectum with imposition of single iliac anus on sigma, which is 54% of all radical operations in the clinic during these years were carried out. 150 patients underwent typical Kenyu-Miles surgery and 200 patients underwent simultaneous rectal extirpation.
On breast cancer recurrence and metastasis after radical mastectomy
Abstract
The material for this work was the data on 490 women with stage I, II and III breast cancer, who were operated on radically in different Saratov hospitals during 13 years (from 1952 to 1964) and afterwards were admitted to Saratov municipal oncologic dispensary. We selected only patients with primary breast cancer whose diagnosis was confirmed by histological examination. The patients were followed up for 5 years.
Serum protein status in the immediate postoperative period in patients with rectal cancer
Abstract
We studied the fractional composition of serum proteins in patients with rectal cancer. We were interested in the deviation of protein metabolism from the norm observed before surgery and immediately after surgery (on the operating table). Patients were examined on the operating table before and after the operation, on the 1-2-3-5-7th postoperative days. Total protein was determined refractometrically, serum protein fractions by electrophoresis on Flin and Meio paper.
On recurrent nephrolithiasis
Abstract
At the Vishnevsky Institute of Surgery from 1961 to 1970, 34 patients (14 men and 20 women aged 9 to 67 years) with recurrent nephrolithiasis were observed. 15 patients were initially operated on in other medical institutions and 19 - in the Institute of Surgery. Nine patients had solitary recurrent stones, 10 had multiple stones, 15 had coral stones, 16 had right-sided stones, 7 had left-sided stones and 11 had bilateral stones.
Morphocycline in the treatment of chronic calculous pyelonephritis
Abstract
In pyelonephritis the infective and inflammatory process is localised not only to the renal pelvis and calyx but also to the renal parenchyma with predominant involvement of the interstitial tissue. The cure requires high doses of antibiotics in both urine and blood, because the infection in the interstitial tissue is only exposed to antibiotics via the haematogenous route. The new antibiotic morphocycline (methylmorpho-lyntetracycline) has proved to be extremely valuable in this respect.
Nephrotoxic poisoning
Abstract
Acute renal failure in poisoning is common, and mortality remains high despite modern treatment methods. A. Y. Pytel and S. D. Goligorski, K.T. Hovnatanyan and others believe that shock leading to renal ischaemia and anoxia is the main cause of acute renal failure in all types of poisoning, but direct nephrotoxic effect of poison on the kidney, and the involvement of an allergic component is not excluded. Acute renal failure develops most frequently in poisonings with acids and alkalis, salts of heavy metals, antifreeze, barbiturates, alcohol and its derivatives, organophosphorus compounds, chlorinated hydrocarbons, salicylates and sulphamides, plant poisons (mushrooms), etc.
On redox processes in digestive diseases
Abstract
The role of the digestive system in the trophic function of the body is well known. Certain pathological conditions of the gastrointestinal tract can lead not only to impaired absorption of metabolic products, but also to changes in the biosynthesis of vitamins, constituting prosthetic coenzyme groups that are involved in redox processes. Hence, the study of the state of metabolic-enzymatic processes in diseases of the mentioned system is obviously of certain importance both in understanding the severity of the disease and in choosing an effective therapy.
The role of lymph circulation in the pathogenesis of peritonitis
Abstract
To clarify the role of lymph circulation in the pathogenesis of the inflammatory process in the abdominal cavity we studied in experiments on 80 dogs and 65 rabbits the course of the experimental peritonitis in the conditions of the thoracic lymphatic duct ligation and drainage as well as the thoracic duct lymph flow in norm and in different terms of peritonitis development (after 3, 6, 12 hours and in the first 4 days). There were 8 dogs in each experimental group and 12 in the control group.
Detection of autoantibodies in thyroid pathology by gel precipitation reaction
Abstract
Sera from 140 patients with various thyroid diseases were tested to detect circulating autoantibodies to thyroglobulin. The immunological test was a semimicro modification of the Uchterloni gel precipitation reaction. Thyroid gland extracts from trauma victims were used as antigen. The extracts were prepared at a ratio of 1:3 (1 part tissue and 3 parts saline).
Surgical treatment of fresh and unhealed fractures of the diaphysis of the femur
Abstract
In the Clinic of General Surgery of Kuibyshev Medical Institute over 15 years (1955-1969) 1348 patients with different fractures of tubular bones were treated. 188 of them (145 men and 43 women at the age from 3 to 83 years) were treated with fresh and not healed fractures of femur diaphysis. Fractures in combination with injuries of other organs were in 50 patients (26.5%): in combination with craniocerebral injuries in 22 patients, with fractures of the pelvis in 5 patients, with injuries of other organs in 1 patient and with concomitant injuries of other organs in 22 patients. There were 165 closed fractures and 23 open fractures. The left hip was injured in 94 patients, the right hip in 92, and both hips in 2.
Direct blood transfusions for burns
Abstract
We used direct blood transfusions in 28 patients aged from 3 to 60 years old with predominantly deep burns of 10 to 40% of the body surface, and in 15 patients of approximately equal severity, a transfusion of preserved blood with a storage time of 9 to 20 days.
Vectorcardiogram for aortic heart disease
Abstract
To clarify the value of VCG in the differential diagnosis of aortic malformations, we examined 80 patients with acquired heart defects (42 women and 38 men aged 17 to 60 years). In 35 of them there was aortic semilunar valve insufficiency in combined aortic or aortic-mitral malformations (the 1st group) and in 45 patients there was aortic orifice narrowing in the mentioned malformations (the 2nd group). All patients had heart defects of rheumatic etiology.
Differential diagnosis of pneumonia and tuberculosis at the present stage
Abstract
The need to differentiate between pneumonia and pulmonary tuberculosis is quite common. In recent years, the diagnosis of these diseases has become more difficult. This is due to the fact that the differences in the clinical course of pneumonia and tuberculosis have become blurred. On the one hand, there is an increase in the frequency of sluggish pneumonia, and on the other hand, there is an increase in the number of persons with minor forms of tuberculosis.
Use of nitrofuran in gynecology
Abstract
According to our clinic and the Department of Microbiology, staphylococci (45%) and Escherichia coli (29.8%) are the leading causative organisms in inflammatory diseases of the female genitalia; streptococci account for only 15.3%; other micro-organisms were isolated from the cervical canal in 9.8% of patients.
Use of 17-oxyprogesterone-capronate in genital endometriosis
Abstract
Among the existing treatments for endometriosis patients, hormone therapy has attracted particular attention in recent years. Experimental and clinical observations have established that the growth and development of endometroid heterotopias occurs against a background of hormonal imbalance in the female body. An increased secretion of oestrogenic hormones and an insufficient function of corpus luteum hormone play a major role.
Percutaneous colpopoiesis for vaginal atresia after radiotherapy
Abstract
G., 32 years old, was admitted on 28/III 1969 for vaginal atresia. She underwent a simple uterine extirpation with appendages in 1961 (diagnosis: uterine chorionepithelioma with metastasis to the anterior vaginal wall). In the post-operative period, which proceeded without complications, she received a full course of combined radiation therapy. She remained under outpatient observation for the following years. In 1963 she received radiotherapy due to a lump in the vaginal stump. Since 1968 she has been experiencing pain and discomfort during intercourse. Pain during sexual intercourse had increased considerably recently, which prompted her to come to the clinic.
Morphogenesis of nerve elements of the artificial vaginal mucosa in women
Abstract
A simple and safe method of artificial vaginal formation with a kapron sieve on a polyethylene protector has been developed at the Department of Obstetrics and Gynaecology No 1 of Kazan HIDUV. Experimental and clinical observations have shown that the kapron sieve becomes a matrix, along the cells of which first young granulation and then mature connective tissue and epithelial lining of the artificial canal are formed.
Intraepithelial cancer and preclinical stages of cervical cancer
Abstract
We examined 137 patients referred to the dispensary from various antenatal clinics in the country with a histological diagnosis of in situ cervical cancer. All the patients were registered. There were 7 women aged 20 to 30, 53 women aged 31 to 40, 38 women aged 41 to 50, 36 women aged 51 to 60 and 3 older. Twenty-two women were menopausal and the rest had menstrual function.
Labor management in women with a uterine scar
Abstract
The main cause of uterine rupture is pathological changes in the uterus, of which postoperative scarring is the most important. It is therefore of great importance to assess the integrity of the postoperative uterine scar. Dual contrast and hysterography are effective methods for determining the completeness of the uterine scar.
Peculiarities of the mental development of children born under obstetric pathology
Abstract
We studied the mental and physical development of 90 children aged 9 to 13 years, born under obstetric pathology. The main emphasis was placed on the study of personality and character formation, intellectual development, and the presence of certain symptoms of higher nervous system disorders. When parents were interviewed, special attention was paid to the course of pregnancy, infectious and other diseases suffered by the mother during this period, her taking fetal drugs during pregnancy and other factors that could adversely affect the developing fetus.
About cancer chemotherapy in an oncology ward
Abstract
Until now only 12% of those who come to our clinic for internal malignancies are curable, 25% can be treated with no guarantee of success and 63% of patients are not curable at all. This dictates that chemotherapy for malignant tumours must be administered in the oncology department of the outpatient clinic.
Primary gallbladder cancer
Abstract
During the last 25 years (1945-1970) 1691 patients with biliary tract diseases were treated in the first hospital surgery clinic of Kuibyshev Medical Institute. Primary gallbladder cancer was diagnosed in 34 patients (32 women and 2 men) (2%). Among 588 patients with reliably confirmed cholelithiasis, gallbladder cancer accounted for 5.8%.
Angiosarcoma of the duodenum
Abstract
Sarcomas of the duodenum are very rare. By 1953, according to S.M. Freidlin, only 80 cases had been published in the world literature, followed by 3 more. More often the disease is diagnosed during surgery or at autopsy. Preoperative diagnosis is extremely rare. The clinical picture of sarcoma, like other tumours of this localisation, lacks sufficiently characteristic symptoms.
Testicular metastases in stomach cancer
Abstract
Metastasis of gastric cancer to the testes, unlike metastasis to the ovaries, is very rare. It is important to know that metastases to the testes can occur while gastric cancer is still latent. We think that our observations may be of some interest.
About torsion of the uterine appendages
Abstract
In view of the rarity of reports of torsion of the uterine appendages in hydrosalpinx, we decided to share our own observation. C., 47 years old, presented on 6/X 1970 with complaints of lower abdominal pain radiating to the right thigh and frequent urination. She had been ill for 14 hours after defecation.
The course of the postpartum period in pregnant women with late-onset toxemia
Abstract
In recent years it has been noted that morbidity and mortality from puerperal septic diseases both abroad and in the USSR have started to increase again. We believe that the solution to the problem of further reduction of postpartum infectious diseases should follow the path of in-depth study of the causes favourable for the development of infectious processes in the body after childbirth. Since late toxicosis is the most frequent complication of pregnancy, it seems important to study its effect on the course of the postpartum period and on the occurrence of puerperal infectious diseases.
Complete calcification of a tuberculous kidney
Abstract
Kidney calcification usually occurs in patients with closed tuberculous kidney disease. The clinical course is often completely silent, and the disease is discovered by chance. Tuberculous renal disease leads to chronic sclerosing paranephritis, with patients presenting to the doctor with complaints of pain in the lumbar region.
Acute retention of urine by a fecal stone
Abstract
F., 6 years old, was admitted on 25/V 1970 from a rural district hospital for urinary retention. The boy was restless, capricious, complained of strong urge to urinate, pain in the lower abdomen. For 3 days he had difficulty in urination, delayed urination for the last 20 hours. Stools were daily, in small amounts, mushy, without pathological impurities. Temperature 37.8°. Respiratory and circulatory organs without pathology. Tongue was clean and moist. The abdomen is not swollen, soft, palpation is painful in the lower parts, over the womb the bladder is identified, the bottom of which is 4 cm below the navel. Finger examination of the rectum at the front of the rectum in the small pelvis reveals a dense tumour-like mass about the size of a woman's fist, immobile, with a smooth surface.
Bladder rupture simulating a pattern of acute renal failure
Abstract
Spontaneous bladder rupture is rare and difficult to diagnose. We observed a patient in whom this pathology was masked by mushroom poisoning complicated by acute pancreatitis with haemorrhagic gastroenteritis and acute renal failure. The true cause of the disease was discovered 2 weeks after the onset of the disease.
Microflora of the nasopharynx in children with acute otoantritis
Abstract
We observed 136 children aged from 2 months to 12 years. Nasopharyngeal secretions were taken from the choanal region with a sterile cotton swab behind the palatine curtain, inoculated on cups with 5% blood agar and in Kitt-Tarzzi broth with 0.1% agar-agar and incubated in a thermostat at 37° for 24 hours. Initial cultures of nasopharyngeal secretions usually showed mixed cultures. Only in 15 observations were pure cultures isolated from nasopharyngeal secretions.
Dynamics of copper levels in the serum of pneumonia patients
Abstract
Micronutrients are among the important chemical factors that play a role in the vital functions of the body, as well as in the pathogenesis of many diseases. One of the vital trace elements affecting the processes of tissue respiration and blood circulation is copper.
Effect of UHF electric field on pancreatic secretory function
Abstract
We studied the effect of a single UHF treatment on fasting glycaemia and on sugar curves after a double glucose load. In addition, we investigated glycaemic curves in connection with a course of UHF treatment. Procedures were performed in oligothermic mode on the pancreas area using transverse UHF-4 and UHF-62 machines.
On the functional status of the small intestine in diabetic patients
Abstract
We examined 58 diabetic patients (38 men and 20 women aged between 20 and 60). Twelve of them had a mild form of the disease, 36 had a moderate form and 10 had a severe form. Enterokinase and alkaline phosphatase activities were studied in duodenal contents, as their activity in feces depends primarily on the functional state of the large intestine and intestinal microflora. Enterokinase activity was determined by the Shlygin method, alkaline phosphatase by the method of Fomina, Mikhlin, Shlygin. The activity of these enzymes in duodenal contents of 18 healthy persons was investigated to control the techniques.
Echoencephalography in the diagnosis of cerebrospinal hypertension
Abstract
To diagnose cerebrospinal hypertension in the acute period and in the following days we applied in 72 patients the method of one-dimensional echoencephalography - ultrasound sonication of the patient's head with the domestic echoencephalograph VNIIMP "ECHO-11". Subsequently, all patients underwent lumbar spinal tap with measuring of cerebrospinal pressure using Claude manometer. In the horizontal position the pressure ranged from 15 to 30 mm aqueous column.
Cardiac muscle abscesses in acute hematogenous osteomyelitis
Abstract
Purulent involvement of the heart muscle is quite common, but abscesses are rare. Myocardial abscesses are the most common pathological finding. Pus is caused by septic emboli or by the contact passage of purulent inflammation from the pericardium and endocardium to the myocardium. The spread of the purulent process through the lymphatic tract is possible.
Towards the diagnosis of cardiac echinococcosis
Abstract
Cardiac echinococcosis is a relatively rare pathology in clinical practice, ranging from 1.08 to 1.75% in relation to all human echinococcal diseases. The greatest number of cases is summarized in monograph of I. J. Deinek (1968) - 160 cases of cardiac echinococcosis, of which 118 are published in foreign literature, and only 42 - in Russian one.
Markiafava-Mikeli disease
Abstract
Although this disease has been described many times in the literature, it is not easy to diagnose and requires some focus in the clinical and laboratory examination of the patient. The difficulty of diagnosis is due to the relative rarity of the disease and the difficult differential diagnosis. For example, our clinic has treated about 22,000 patients in the last 11 years, and Markiafava-Mickeli disease has been encountered in only 2.
About the treatment of Reiter's syndrome with griseofulvin
Abstract
Urethro-oculo-synovial syndrome (Reiter's syndrome) is known to consist of purulent urethritis, purulent conjunctivitis and arthritis. The etiology of the syndrome is still an open question. Recently, a specific pathogen (virus) has been reported. Reiter's syndrome is considered by most researchers to be a variant of rheumatoid arthritis.
Resuscitation for generalised tetanus
Abstract
Specific prevention of tetanus by active and passive immunisation has been shown to be brilliantly solved. But in general the problem remains unsolved, as there is no effective therapy and in every case of general tetanus the prognosis remains doubtful. Treatment essentially begins only when toxin fixation has already taken place in the tissue structures and when the elimination of the pathogen and the free toxin produced by it can no longer interrupt the chain process of disease development. Etiological therapy plays no significant role here. The centre of gravity is transferred to pathogenetic therapy, in which an important place is given to non-specific resuscitation measures.
Oxygen inhalation under increased pressure for tetanus
Abstract
Advances in recent decades in the study of the effects of increased oxygen pressure (O2P) on the body have allowed this method to be used in a number of surgical infections. The first attempt to use MPC in tetanus was successful, saving 15 out of 16 patients. Since there is still very little experience in tetanus treatment with this method, we thought it appropriate to cite our observation.
Organisation of surgical care for acute abdominal problems in a rural area
Abstract
The most complex issue in the organisation of surgical care for the rural population is the provision of emergency surgical care. The emerging general trend towards specialised medical care in central district hospitals is not yet supported by clear scientific, practical and methodological guidelines for emergency surgical care.
Functional pathology of atherosclerosis
Abstract
The book by Prof. L.S. Schwartz is written on a timely topic and is of interest to physicians of many specialities. The author approaches the study of atherosclerosis from the perspective of assessing the functional state of the most important body systems: respiration, blood circulation and digestion. His studies are based on a large number of his own observations (more than 3500 patients). The bibliography contains 468 sources in Russian and 182 in foreign languages.
Anaesthesia in burn victims
Abstract
The monograph summarizes the experience of anaesthesiological work of the thermal lesions clinic of the Order of Lenin Red Banner Military Medical Academy named after S. M. Kirov, one of the largest burn centers in the USSR. It summarises the experience of anaesthesiology at the Thermal Injuries Clinic of the Kirov Military Medical Academy, one of the largest burn centres in the USSR.
Associate Professor Salikh Girfanovich Faizullin
Abstract
On June 10, 1971 Salikh Girfanovich Fayzullin, former vice-rector on educational work, associate professor of the Chair of Biology of Kazan Red Banner of Labour Medical Institute, candidate of biological sciences, CPSU member since 1944, passed away at the age of 67.
Chronicle
Abstract
On March 17, 1971 at the joint session of the Board of the TASSR Ministry of Health, the Presidium of the Regional Committee of the Trade Union of Medical Workers and the Republican Committee of the Red Cross Society the results of the public inspection of the health care institutions in the Tatar ASSR for 1970 were discussed.