Vol 81, No 3 (2000)

Theoretical and clinical medicine

Prevalence and prevention system of congenital malformations in the Republic of Tatarstan

Shaikhutdinova L.N.


The prevalence of congenital developmental defects among children in Tatarstan Republic and its dynamics for the last five years are studied. Their role in mortinatality structure, infant mortality is analyzed. The program of preventing congenital defects by creating the prenatal diagnosis service including the US screening of pregnants, medicogenetic consultation, invasive methods of prenatal diagnosis is suggested. The introduction of the current monitoring of congenital developmentale defects is necessary to control the efficiency of the suggested prevention measures.

Kazan medical journal. 2000;81(3):161-164
pages 161-164 views

Place of palliative operations in the treatment of patients with tetralogy of Fallot

Mirolubov L.M., Petrushenko D.Y., Zakharov A.A., Kalinicheva Y.B., Sabirov D.R., Arzin D.N., Singatullin M.G., Biktasheva L.Z., Khamidullin A.F.


As many as 42 children with the Fallot’s tetrad aged 3 months to 9 years, 32 (78%) children up to 3 yeaes were examined and operated in the cardiac surgery department of the Children Medical Center of Kazan from 1995 to 1998. The palliative operations were performed in 30 patients. The radical correction of the Fallot’s tetrad was performed in 17 patients, it was repeated in 5 children in terms from 1 to 3 years after the previously performed palliative operations. Mortality was not high. In various age groups the differentiated approach taking into account the initial state gravity makes it possible to obtain good result? in the treatment of one of the most dangerous congenital heart diseases. Urgent palliative operations make it possible to save life of patients of early age and to prepare them for radical operations.

Kazan medical journal. 2000;81(3):165-166
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On the health of preschool children born prematurely

Albitsky V.Y., Mendelevich V.D., Galiyeva S.K.


The combined clinical social examination of 118 children prematurely bom of the I—II degree is earned out. As many as 118 children bom at full tenns, selected as case-control (by sex, age) are examined for comparison. The preschool aged children prematurely born children had higher morbidity level according to taking medical advice, examination data including psychic behaviour disorders and insufficient physical development. The obtained results should be taken into account in clinical examination of such children.

Kazan medical journal. 2000;81(3):167-169
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Influence of a combination of dimephosphone and xymedon on the state of local immunity of the oral cavity

Gilyazeva V.V.


The effect of the combination of ultraphoresis of 15% dimephosphone aqueous solution and administration of xymedone on the local immunity state of oral cavity in combined prevention of dental caries is estimated. The used treatment promotes reliable improvement of the local immunity indicators of oral cavity.

Kazan medical journal. 2000;81(3):170-171
pages 170-171 views

Changes in the activity of enzymes in the blood in nonspecific lung diseases

Khamitova E.G., Khamitov R.F., Zakirova A.K.


Level of different ensymes was determined in blood serum of patients with bronchial asthma, chronic obstructive bronchitis, chronic nonobstructive bronchitis, pneumonia and 22 healthy persons. In severe chronic obstructive bronchitis in contrast to bronchial asthma, the increase of activity in blood serum was found which can serve as a differential and diagnostic indicator. In the acute phase of pneumonia and severe chronic nonobstructive bronchitis the increase of alkaline phosphatase, gamma-glutanul transferase activities occurred, and in pneumonia activity of aminotransferases increased as well. By discharde of patients from the hospital the studied indicators remained elevated. It is necessary to continul the search of further ways of Correction of enzyme changes with estimation of prognostic value of some indicators in case of favoreble outcome of pulmonary diseases.

Kazan medical journal. 2000;81(3):172-175
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Comparative assessment of the working capacity of patients with peptic ulcer after resection of the stomach according to Billroth I and II and duodenopyloroplasty

Naumov V.F., Minkhairov R.G., Mustafina Z.Z., Mrasov N.M., Shameeva F.Z.


The comparative estimation of labour capacity after two various operation methods: standard stomach resection and duodenopiloroplasty is given. It is established that the organopreserving operation method provides higher health level of the patient with peptic ulcer. The suggested method is efficient in medical as well as in social and economic aspect.

Kazan medical journal. 2000;81(3):176-178
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Biliary fistulas

Hunafin S.N., Vlasov A.F., Nurmukhametov A.A., Gattarov I.K., Bulgakov V.R., Aminev D.Z., Murzin G.A.


The results of the treatment of 27 patients with biliobiliary fistulas — serious complications of cholelithiasis which for the most part were not diagnosed before operations and were unexpected during interventions as to cholecystitis or mechanical jaundice are given. The operative treatment presents difficulties and should be directed both to tte elimination of biliobiliary fistulas and to the correcti® of patholigic changes in biliary ducts. Five cases of successful treatment of biliobiliary fistulas by miniaccess are given. The postoperative mort ality was 22,2%.


Kazan medical journal. 2000;81(3):179-180
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Possibilities and prospects of minimally invasive surgery for varicose veins

Belyaev M.V.


The described ambulatory treatment method of varicosis of the II—III degree makes it possible to extend the indications to the conservative treatment, on veins and to obtain the steady good effect comparative with the operative phlebectomia effect but without its traumatism, to achieve high cosmetic results and fast recovery of capacity for work.

Kazan medical journal. 2000;81(3):181-184
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Detection of hemocoagulative activity of leukemia cells in acute myeloid leukemia and chronic myeloid leukemia

Zubairov D.M., Andrushko I.A., Zubairova L.D., Svintenok G.Y., Akhmadeev A.R., Grigoriev V.N., Nekhoroshkova Z.M.


Peripheral blood and punctates taken in 13 primary patients, 6 of which had acute myeloblastic leukemia and 7 — chronic myeloleukemia are studied. The peripheric blood in 3 healthy volunteers is studied for control. The method of revealing the tissue factor activity in blood cells of patients with leukemia is suggested. Previously described expression of the tissue factor by myeloblasts of patients with acute myeloblastic leukemia in peripheral blood as well as in bone marrow punctates is confirmed. It is shown that in patients with chronic myeloleukemia expression of the tissue factor activity is carried out by myeloblasts in peripheral blood as well as in bone marrow punctates. The results contradict the conception maintaining the principal impossibility of forming principal the tissue factor by blood cells. The development of disseminated intravascular blood coagulation syndrome and hemophilia under the influence of the tissue factor in leukocytes is possible not only in acute myeloblastic leukemia but in chronic myeloleukemia.

Kazan medical journal. 2000;81(3):185-187
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Influence on the process of glycation of serum albumin of synthetic antidiabetic agents

Kulagin O.L.


Synthetic antidiabetic agents (glyphormin, glyclaside, glycvidone, glybenclamide) in incubation of high concentrations of glucose with human serum albumin in experiments in vitro can diminish glycation process. In mild glycation regime the effect of agents becomes more prolonged and pronounced. The protein glycation leved in constant glucose concentration in rats with alloxan induced diabetes decreases while injecting them with glyphormin, glycvidone and and glybenclamide during a month

Kazan medical journal. 2000;81(3):188-191
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Influence of chloditan on the content of glycosaminoglycans in the blood and liver of rats with alloxan diabetes

Batting A.A., Butolin E.G.


Hypoglucocorticoidemia caused by systemic injection of chloditane {[2(chlorphenil)-2-(4- chlorphenil)-l]-l dichlorethane} promotes normalizing the content of glycosaminoglykanes in blood of rats with alloxan diabetes. The increase of concentration of the total glycosaminoglykanes in liver tissue of these rats on the 30th day occurs as a result of the accumulation. The determination of the content W sulphatized glycosaminoglykanes can be used to reveal the metabolic disorders in the connective matrix in alloxan diabetes.

Kazan medical journal. 2000;81(3):192-194
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On the mechanism of hepatocyte proliferation induced by lead nitrate

Valeeva I.K., Gumerova A.A., Kiyasov A.P.
Kazan medical journal. 2000;81(3):195-197
pages 195-197 views

Criteria for evaluating the syndrome of endogenous intoxication in peritonitis

Malkov I.S., Shaimardanov R.S., Korobkov V.N., Sharafislamov I.F., Baydin I.N., Talalin L.A.


The laboratory and instrumental criteria are developed for the objective estimation of the endogenous intoxication syndrome in peritonitis. The neutrophil reactive response index in 210 patients and ultrasound morphometry of the enteric wall in 54 patients with diffuse peritonitis along with clinical and biochemical investigation methods make it possible to concretize endotoxicosis degree and treatment efficiency.

Kazan medical journal. 2000;81(3):198-199
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To substantiate the functional diagnosis of organic mental disorder in forensic psychiatric practice

Vandysh V.V., Tabeeva D.M.


The vegetative reactions using functional tests (correlation rhythmography and electronic conduction) were studied in 165 inpatient men with organic brain lesions during forensic and psychiatric examination. These methods can be used in expert practice

Kazan medical journal. 2000;81(3):200-203
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Diagnosis and treatment of tubal pregnancy by endoscopic method

Budaev A.I., Gorin V.S., Shin A.P., Rybnikov S.V.


As many as 242 women with extrauterine pregnancy were operated using the endoscopic method. The removal of uterine tube was carried out in 157 women with pronounced changes of uterine tube, the reconstructive operation with preserving of the tube was carried out in 87 women. The removal of fetal ovum was carried out by squeezing or vacuumaspiration with the following retrograde hydrotubation. The tube part was removed with application of tubotubar anastomosis in 32 women. Hysterosalpin- gography and kymotubal insufflation showed the efficiency of organ saving operations. The use of endosurgical treatment methods of extrauterine pregnancy made it possible to avoid laparatomy in tubal pregnancy excluding hemorrhagic shock caseg.

Kazan medical journal. 2000;81(3):204-206
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Systemic and regional hemodynamic disorders of the mother and fetus in preeclampsia

Melnikov V.A.


As many as 438 women were examined during the pregnancy by the complete “blind” screening method. The blood circulation indices, in vascular regions of brain, chest, abdominal cavity, lower extremities, fetoplacental system are studied in active orthostasis and in the side position of a pregnant women. It is revealed that hemodynamic disorders in greater and lesser circulation are easily found in examination of pregnants in active orthostasis and cause gestosis in early terms of pregnancy.

Kazan medical journal. 2000;81(3):207-210
pages 207-210 views


Clinical significance of determining the ion-transport functions of cell membranes in hypertension and its cerebral complications

Oslopov V.N., Zabbarova A.T., Bogdanov E.I.


Development of methods for early diagnosis of diseases, prediction of the course of pathological processes are among the priority areas in medicine. Studies of cellular ion-transport systems turned out to be promising for solving these problems. Thus, it was established [46] that for a number of diseases — some types of epilepsy, migraine, episodic ataxia, periodic paralysis — channelopathies are the primary link in pathogenesis, and in the treatment of these diseases, agents stabilizing the operation of ion channels are effective.

Kazan medical journal. 2000;81(3):211-216
pages 211-216 views

Apoptosis: characteristics, methods of study and its role in the pathogenesis of atopic diseases

Boychuk S.V., Mustafin I.G., Fassakhov R.S.


There are two forms of cell death - necrosis and apoptosis. Necrosis is the death of cells under the influence of damaging agents external to the cell and inadequate environmental conditions (pH changes, mechanical influences, temperature changes, exposure to factors that damage the cell membrane, etc.). Necrosis is manifested in the swelling of the cell, accompanied by a rupture of the membranes due to an increase in their permeability and the release of the contents of the cell into the environment. Cell death due to necrosis is observed, in particular, in inflammatory reactions.

Kazan medical journal. 2000;81(3):217-222
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The prevalence of cerebrovascular pathology

Ismagilov M.F., Shapoval I.S.


In recent years, the prevalence of cerebrovascular pathology has increased among both elderly and younger people. Among the causes of death, it ranks second (after acute heart disease), and in terms of disability, it ranks first (3.2 per 10,000 population) [6].

Kazan medical journal. 2000;81(3):223-225
pages 223-225 views

Short articles

Diagnostic aspects of primary hyperparathyroidism

Pecherskaya G.A., Ishenin Y.M.


In recent years, there has been a revision of the concept of primary hyperparathyroidism (PHPT), which, according to available data, is the third most common endocrine disease.

Kazan medical journal. 2000;81(3):226-227
pages 226-227 views

A case of successful treatment of twelve-day hypoglycemic coma

Bulashova O.V., Jesters A.V., Saetgaraev A.K., Bulatov T.V., Sharapova L.A., Akhmetova D.K., Yapparov I.G.


The development of hypoglycemic coma is a severe complication of insulin therapy for diabetes mellitus. According to the literature, being in a hypoglycemic coma for more than 12 hours is associated with a threat to life due to the development of decortication and leads to high mortality. Most often, hypoglycemic coma occurs as a result of the administration of insulin in combination with the intake of large amounts of alcohol against the background of insufficient food intake. The patient's condition in connection with the intake of alcohol is underestimated by others, which leads to late hospitalization and, accordingly, to severe outcomes.

Kazan medical journal. 2000;81(3):228-228
pages 228-228 views

Visceral leishmaniasis in Kazan

Khaertynov H.S., Abilmagzhanova L.M., Avdeeva N.N.


In Tatarstan, cases of infections that did not occur before began to be noted. One of them is leishmaniasis, a protozoal vector-borne infection caused by intracellular parasites of the genus Leishmania transmitted by mosquitoes. With this type of infection, mainly the internal organs (visceral form) or the skin and mucous membranes (cutaneous form) are affected. In the CIS, it is registered in the countries of Central Asia and the Caucasus. In Kazan, over the past 2 years, 2 cases of visceral leishmaniasis were detected, imported from Georgia and Tajikistan. In both cases, the patients were children: in the first, the Mediterranean-Central Asian variant was diagnosed, in the second, the Indian variant.

Kazan medical journal. 2000;81(3):227-228
pages 227-228 views

Glomus tumor of the nail phalanx of the fingers and its treatment

Nettov G.G.


In medical practice, patients are quite rare, mostly women, who complain of pain in the nail phalanx of the fingers. Gradually intensifying, the pains are localized in the area of ​​the nail plate, drag on for years, reaching great intensity. In our opinion, such patients are unreasonably long and unsuccessfully observed and treated by various specialists under different diagnoses. While a correct diagnosis and timely surgical intervention relieve the patient of all suffering and lead to a full recovery.

Kazan medical journal. 2000;81(3):228-229
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A case of scapular avulsion with upper limb

Mikusev G.I., Khaidarov F.F., Gainullin R.U., Akhmetzyanov N.N.


Limb avulsions are the most severe injuries of the musculoskeletal system. Among the causes of damage, separations due to the ingress of limbs under rail transport, into working machines and units, dominate. Bleeding from the wound with this type of injury is usually insignificant or absent at all, which is explained by damage to the wall of the main vessels at different levels. The thrombus in the lumen of the stump is intertwined and firmly held by all the shells of the ruptured vessel. The most severe injury is the complete separation of the scapula with the entire upper limb. Rapid rotation of the arm leads to twisting of the tunicae externae of large vessels, there is no severe bleeding when the limb is torn off.

Kazan medical journal. 2000;81(3):229-230
pages 229-230 views

Healthcare mangement

Radiation diagnostic centers in the healthcare system

Bakirov R.S., Yarullin A.K., Zaripov R.A.


The decrease of the number of patients from 15,3 to 7,8% with the first revealed pathology late in the course of the disease without essential treatment effect and their growth from 36,5% to 46,5% with early diagnosis and steady positive treatment results are due to the organization in 1995 of the diagnostic centers in Tatarstan Republic. The positive results obtained show the high treatment efficiency, medical, social and economic profitability of diagnostic centers as one of the important subsystems of health protection.


Kazan medical journal. 2000;81(3):231-233
pages 231-233 views

Assistance to the practicing physician

Clinic and diagnosis of toxocariasis in children

Bulatov V.P., Petrova T.P., Cherezova I.N., Makarova T.P.


Toxocariasis is a zoonotic invasion with a long relapsing course (from several months to several years) and polymorphic clinical manifestations of an immunological nature. The causative agents of toxocariasis belong to the class of roundworms of the genus Toxocara. Two species of this genus are known: T. canis is a helminth of the canine family and T.cati is a helminth of the cat family. The role of T. canis in human pathology has been firmly established, and T. cati is still under discussion. These nematodes are widespread in cats and dogs. Affected animals excrete a huge number of eggs with feces, causing a high contamination of the soil. Up to 50% of samples from children's sandboxes contain invasive toxocara eggs, which are very resistant and persist in the soil for several years. Children under 5 years of age are most commonly infected. The main source of infestation for children are dogs, especially puppies. Infection occurs through direct contact with an infested animal whose coat is infected with infective eggs. Children with geophagy are most at risk of infection, especially when playing in the sand or with a dog.

Kazan medical journal. 2000;81(3):234-236
pages 234-236 views


Outstanding organizer, scientist, surgeon Rustam Allamovich Vyaselev


May 2000 marked the 100th anniversary of the birth of one of the most famous leaders of the Kazan Medical Institute, the head of the Department of Hospital Surgery, Professor Rustam Alyamovich Vyaselev. He headed the institute from February 1947 to December 1963. It was a rather difficult period, including difficult post-war years. Under the leadership of R.A. Vyaseleva Institute not only strengthened its position as one of the largest medical universities, but also made significant progress in its development.

Kazan medical journal. 2000;81(3):237-238
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Academician Boris Alekseevich Korolev and his school


The scientific and medical community of the Russian Federation celebrated the 90th anniversary of Boris Alekseevich Korolev, an outstanding scientist, patriarch of surgery, founder of the scientific and surgical school, academician of the Russian Academy of Medical Sciences, Hero of Socialist Labor, Honored Scientist of the RSFSR, laureate of the Nizhny Novgorod Prize, honorary citizen of the city of Gorky, holder of two orders of Lenin, the Order of the Red Banner of Labor, the October Revolution, many medals and other awards.

Kazan medical journal. 2000;81(3):239-240
pages 239-240 views

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