Vol 62, No 3 (1981)
Possibilities of recognizing the clinical stages of ischemic heart disease according to the data of plasma and vascular-platelet hemostasis
Abstract
56 indicators of the blood coagulation and fibrinolysis system were studied in 866 men, healthy and suffering from coronary artery disease. Based on the mathematical analysis, tables of the significance of individual indicators for recognizing the clinical stages of coronary artery disease were compiled.
Risk factors for heart rupture
Abstract
Based on the study; Risk factors of rupture were identified in 141 cases of heart ruptures in the acute period of myocardial infarction. These include: age over 55 years in men and over 60 years in women with a history of hypertension, high blood pressure after the development of myocardial infarction, extensive damage, the first three days from the moment of illness.
The content of potassium and sodium in the heart muscle in myocardial infarction
Abstract
In 11 deaths from myocardial infarction and in the experiment in animals subjected to ligation of the anterior interventricular artery of the heart, the content of Na+ and K+ in the myocardium was determined. In the ischemic zone, the content of K+ is reduced, and Na+ is increased. These changes occur even before the appearance of morphological signs of myocardial infarction.
Damage to cytoplasmic membranes in patients with acute myocardial infarction
Abstract
The dependence of damage to the outer cell membranes in patients with acute myocardial infarction on the characteristics of the fractional distribution of cholesterol was studied. Determination of 5-nucleotidase activity is an objective criterion for assessing damage to the outer cell membranes, which can be considered a risk factor for thrombus formation and progression of coronary heart disease.
Comparative study of paracoagulation tests in acute myocardial infarction
Abstract
Ethanol, ß-naphthol (test for "fibrinogen B") and protamine sulfate tests, performed simultaneously in the blood plasma of patients with acute myocardial infarction, showed a high degree of correlation with each other, but they differed in sensitivity: ethanol> ß-naphthol> protamine sulfate. Heparin did not distort the results of the ethanol and β-naphthol tests, while the protamine sulfate test results strongly depended on the presence of heparin. The formation of a granular precipitate is not a positive protamine sulfate test and indicates hyperheparinemia. The ethanol test on the basis of data can be recommended to monitor the state of the hemocoagulation system in acute myocardial infarction, including the period of heparin therapy.
Combined treatment of patients with myocardial infarction with combinations of retabolil with panangin and methyluracil with panangin
Abstract
With the help of 131I-albumin, as well as some biochemical methods, the dynamics of protein and electrolyte metabolism in patients with myocardial infarction was studied during the treatment with combinations of steroid anabol retabolil with panangin (47 people) and nonsteroidal anabolizer methyluracil with panangin (35 people). Revealed anti-catabolic effect of the above combinations.
Changes in the blood vessels of the lungs in patients with acute myocardial infarction
Abstract
Analysis of radiographs of the lungs and case histories of 80 patients who were hospitalized for acute myocardial infarction revealed a direct relationship between the width of the right pulmonary artery and the value of the Moore index on the degree of stagnation in the pulmonary circulation. These values were greatest in alveolar pulmonary edema.
On the effectiveness of papaverine, erinitis and euphyllin in patients with angina pectoris
Abstract
As a result of treatment of 90 free angina pectoris with papaverine, erinitis and euphyllin, most of them experienced significant subjective improvement and increased exercise tolerance. The therapeutic effect of the use of the studied antianginal drugs was largely due to a decrease in blood pressure at rest, as well as in heart rate and blood pressure during exercise. Among the indicated coronary active agents, the best results were provided by aminophylline, the second most effective was erinitis, and the third was papaverine.
The therapeutic effect of Siberian adonis in case of circulatory failure
Abstract
Treatment of patients with circulatory insufficiency of I and IIA stages with Siberian adonis provides a significant clinical effect; its influence on the dynamics of electrocardiogram indices, the phase structure of systole, the content of potassium and sodium in the blood and daily urine and the state of the minute blood volume is similar to the action of the spring adonis.
Influence of complex therapy with strophanthin, curantil and heparin on the state of central hemodynamics and microcirculation in patients with chronic circulatory insufficiency
Abstract
Under the influence of treatment with a combination of strophanthin, curantil and heparin in patients with chronic circulatory insufficiency, indicators of central hemodynamics, tissue blood flow and microcirculation improved. The research results give reason to consider the proposed drug combination as an effective means for the course treatment of patients with chronic circulatory failure.
The use of vetrazine for the treatment of cor pulmonale
Abstract
Treatment of cor pulmonale with vetrazine gave a pronounced therapeutic effect, indicating an improvement in hemodynamics in the pulmonary circulation and a decrease in the load on the right heart. The research results give reason to recommend the inclusion of vetrazine in the complex treatment of cor pulmonale.
Comparative evaluation of corrected orthogonal and 12 conventional ECG leads in the diagnosis of ventricular hypertrophy in children
Abstract
Using corrected orthogonal (ECG system Frank and 12 conventional leads, 525 children were examined: 300 healthy children, 125 with heart defects leading to right ventricular hypertrophy, and 100 with breeds leading to left ventricular hypertrophy. Criteria for diagnosing hypertrophy of the right and left ventricles were developed. heart in children 3-7 and 8-15 years old Comparative analysis of the results indicates a higher sensitivity of the Frank system compared with 12 conventional leads in identifying left ventricular hypertrophy in children.
Features of the course of modern rheumatism
Abstract
The case histories of 360 patients with rheumatism were analyzed. Variants of the clinical course of primary and recurrent rheumatism are described. In view of the high frequency of latent and oligosymptomatic rheumatism, attention is drawn to the difficulties in diagnosing primary rheumatism proceeding according to the cardiac type, which is often the reason for its late diagnosis.
Autovenous bypass surgery for occlusive lesions of the femoral and popliteal arteries
Abstract
The results of 89 bypass grafting operations with a reversed autovein in occlusions of the femoral and popliteal arteries were analyzed. The immediate results were recognized as good and satisfactory in 84% of patients, long-term - in 64%. The reasons for the immediate poor results are technical errors and infection, the deterioration of long-term results is associated with the progression of the underlying disease and unjustifiably extended indications for operations. The great saphenous vein in most cases is quite suitable for bypass surgery.
Surgical method of treatment of patients with thromboangiitis obliterans of the lower extremities
Abstract
The operation technique for the surgical treatment of thromboangiitis obliterans of the lower extremities is described. 42 patients with stages II, III and IV ischemia were operated on. In the II Art. ischemia is recommended to perform tecectomy. In the III Art. ischemia in the presence of segmental occlusions tecectomy is combined with autovenous plastic or thromboendarterectomy.
On the diagnosis and treatment of gynecological peritonitis
Abstract
The case histories of 81 patients with gynecological peritonitis were analyzed. 80.2% of patients with this complication were between the ages of 20 and 40. The use of local hypothermia along with drug therapy in the acute period and a rational regimen of nursing patients made it possible to reduce the percentage of surgical interventions to 13.6%, and mortality to 1.2%. The discharge of patients from the department with full rehabilitation contributed to a sharp decrease in the frequency of recurrence of inflammatory diseases.
Dependence of cerebral hemodynamics of newborns on the duration of labor
Abstract
Methods of rheoencephalography and ultrasound examination of the blood flow velocity in the carotid and vertebral arteries were used to study the state of cerebral circulation in 132 full-term newborns, depending on the duration of labor. An adverse effect on cerebral hemodynamics of both rapid labor and labor lasting more than 15 hours has been established. It is recommended to use antispasmodics and tocolytics for the purpose of intrandtal prophylaxis of cerebral circulation disorders in rapid labor.
The role of impaired blood supply to facial muscles in the occurrence of algic manifestations in secondary contracture
Abstract
A rheographic study of the blood supply to the facial muscles in patients with neuritis of the facial nerve and secondary contracture of the facial muscles was carried out. In the acute stage of neuritis, stagnant changes in the hemodynamics of the face were found. A significant difference in blood flow was revealed in patients with contracture of the facial muscles, depending on the presence of pain manifestations or their absence. Algic forms of contracture are characterized by a deterioration in both arterial inflow and venous outflow.
Immediate and long-term results of cervical cancer treatment
Abstract
An analysis of the results of treatment of 124 patients with stage I cervical cancer showed that with a depth of invasion of up to 3 mm, the volume of surgical intervention can be reduced to a simple extirpation of the uterus without risk to the patient's health and life.
Complications of central venous catheterization
Abstract
For two years we have performed 250 central catheterizations veins (subclavian - 187, femoral - 63) in 202 patients. In 26 of them, catheterization was performed twice, and in 11 - three times. The duration of the stay of the catheter in the vein ranged from several hours to 46 days, on average 5-7 days. Most often, we used catheterization of the central vein in patients requiring continuous parenteral nutrition (122), with acute massive blood loss (57), and in 23 patients the reason for catheterization was terminal conditions. Complications were observed in 23 patients (11.4%). They can be divided into 2 groups: complications associated with a violation of the catheterization technique, and complications caused by prolonged presence of the catheter in the lumen of the vein. There were no fatal complications, however, any of them posed a threat, especially with delayed recognition, and always aggravated the patient's condition.
About ruptures of the heart muscle in myocardial infarction
Abstract
The medical histories of those who died from heart rupture (PC) were analyzed. Of the 1499 patients with myocardial infarction (MI) who were admitted to the specialized department for patients with myocardial infarction from 1972 to 1978, 221 died; PC was the direct cause of death in 56 of them (25.3%). MS was mainly observed in the elderly, more often in women than in men. In the 51-60 age group, PC occurred in 5 out of 284 men (1.8%) and in 3 out of 70 women (4.3%), in the 61-70 age group - in 8 out of 270, respectively (2.9 %) and 18 out of 191 (9.4%); in the group of MI patients over 70 years old - in 5 out of 107 (4.7%) and in 17 out of 155 (10.9%). In all patients, MS occurred against the background of transmural MI in the anterior wall region. More often MS was observed in primary MI (76.7%), in 2 cases with repeated MI (3.3%), in 12 with recurrent MI (20.0%). On the first day of myocardial infarction, cardiac rupture occurred in 30 patients, on days 2-3 - in 10, on 4-7 - in 2, on 19-23 - in 8. All cases of late ruptures (after 7 day) were associated with recurrent myocardial infarction.
Rare variant of Wolff-Parkinson-White syndrome
Abstract
It has now been established that the occurrence of Wolff-Parkinson-White (WPW) syndrome is directly related to the presence and functioning of additional muscular pathways through which excitation is carried out from the atria to the ventricles.
Nonparasitic liver cyst
Abstract
The clinical picture of nonparasitic liver cysts is characterized by poor symptoms and depends primarily on the size of the cyst, its location and complications. Patients complain mainly of dull and bursting pains in the right hypochondrium, epigastrium, as well as a feeling of discomfort and enlargement of the liver and abdomen.
Detection of biliary dyskinesias in children with five-fraction duodenal intubation
Abstract
With continuous five-fraction duodenal intubation, the volume of individual portions of bile, the time and rate of their release in one minute are taken into account. There were 213 children under our supervision — 127 girls and 86 boys aged 5 to 14 years. All children were admitted to the hospital for pain and abdominal pain, more often in the right hypochondrium. Half of the children complained of nausea, vomiting, and intestinal dysfunction. Palpation of the abdomen revealed pain in the right hypochondrium, often revealed tension in the abdominal muscles in the choledocho-duodenal zone. In 32 children, the liver was palpated 1.5-2 cm below the costal arch.
Study of bile lipoproteins in patients with cholecystitis in the age aspect
Abstract
The lipid complex (LC) of bile was studied by electrophoresis in polyacrylamide gel (PAGE) in 103 patients; in 86 with chronic non-calculous cholecystitis (30 children and 56 adults) and in 17 with chronic calculous cholecystitis (age - from 36 to 54 years). For control, we studied the lipid profile of bile in two age groups of 20 people in whom the diagnosis of cholecystitis was rejected after a thorough examination.
The use of intrauterine devices immediately after medical abortion
Abstract
Since 1979, we have been introducing intrauterine devices (Lips loops made of polyethylene of Kazan production) immediately after a medical abortion (immediately after the end of curettage of the uterine cavity) to all women who wish, who have no contraindications to this.
To the prevention of postoperative thromboembolism in gynecological patients
Abstract
A complex of reasons plays a role in the occurrence of postoperative thrombosis, among which the leading place is occupied by an increase in the thrombogenic properties of blood, as well as a violation of its rheological properties. These circumstances were the reason for the development of a method for active management of the early postoperative period with the use of non-specific and specific prevention of thromboembolic complications.
Some indicators of the state of the nervous and sympathetic-adrenal systems in workers in the production of lead batteries
Abstract
For three years, dynamic observation and in-depth examination of workers in contact with lead was carried out. 420 people were examined - 130 women and 290 men. 35.5% of them were under the age of 30, the rest were older. 52.4% of the surveyed had a production experience of up to 10 years and 47.6% - more than 10 years. The control group (80 people) consisted of machine shop workers who worked in similar conditions, but without contact with lead.
Contact activation of the Hageman factor
Abstract
The Hageman factor (contact factor, or clotting factor XII), first discovered by Ratnoff and Kololi in 1955, has long been considered responsible for the primary activation of the coagulation cascade through the internal thrombin pathway. It is well known that the formation of active factor XII occurs upon contact with negatively charged surfaces: celite, glass, kaolin in vitro, collagen, damaged vascular endothelium and basement membrane in vivo. Further studies have shown that several plasma proteins are involved in the contact activation process: factor XII, factor XI or plasma thromboplastin precursor, precallikrein, high molecular weight kininogen. Currently, knowledge about the "trigger" mechanism of the contact phase, which leads to the activation of coagulation systems, kinin formation and fibrinolysis, has been significantly expanded.
Physiological and hygienic assessment of the working conditions of foremen of machine-building enterprises
Abstract
A comprehensive physiological and hygienic examination of the working conditions of foremen of machine-building enterprises was carried out. The duties of the foremen include solving a number of organizational tasks, the implementation of which is associated with being directly in the shop for 60% of the working time. Physiological studies have established a decrease in the work capacity of foremen by the end of the working day due to an increase in fatigue.
Application of a dry differential medium to distinguish pathogenic from non-pathogenic Neisseria
Abstract
A dry differential semi-synthetic medium to distinguish meningococci from non-pathogenic Neisseria was tested with 306 freshly isolated Neisseria strains. Tests have shown the high diagnostic value of the environment. It is convenient to prepare and easy to use.
On the advantages of a photo-recording oscilloscope in the study of the main blood flow of the artery of the extremities
Abstract
Comparison of the data of oscillographic studies on devices with an ink-recording recorder and with photographic recording in healthy individuals and in patients with obliterating diseases of the arteries of the lower extremities has been carried out. The OGAF-026 oscilloscope is more sensitive and registers collateral pulsation with well-developed collateral vessels. Oscillographic examination in the postoperative period objectively reflects the effectiveness of reconstructive surgery. At the same time, the method cannot be used to control the effectiveness of conservative treatment, since it does not register changes in microcirculation.
Professor Alexander G. Korotkov
Abstract
May 5, 1981 marked the 60th anniversary of his birth and 36 years of scientific, pedagogical and social activities of the head of the Department of Normal Human Anatomy of the Kazan Medical Institute, Honored Scientist of the TASSR, Professor Alexander Grigorievich Korotkov.