Vol 77, No 4 (1996)

The complex medical and population genetic stu dy is performed in 5 districts of Mari El Republic (Gornomarisky, Orshansky, Morkinsky, Sovetsky). The units of autosomal recessive pathology are found in 115 families with 137 patients. The high level of dependence of the load of autosomal recessive pathology on inbreeding is shown.

The population genetic study of hereditary nervous disorders is performed in Mari El (6 regions, total population 224100, including 144100 ethnic Maries and 66100 ethnic Russians). Overall hereditary nervous disorders prevalence is 25,44 per 100000, including 21,86 in Maries and 32,52 in Russians, the load of X-linked and autosomal recessive disorders being heavier than that of autosomal dominant disorders. The hereditary nervous disorders spectrum includes 24 nosologies neuromuscular disorders predominantly. Clinical and genetic characteristics of some cases are presented.

The results of the study of qualitative signs relationship with peculiarities of the course and outcome of acute pneumonias are presented. One of the adequate methods of the estimation of qualitative signs relationship using χ² is used.

The use of xymedone in combined specific chemotherapy in disseminated forms of pulmonary tuberculosis results in more pronounced therapeutic effect than the use of pure base therapy. The immunomodulating effect can be one of the mechanisms of the drug action providing positive clinicoroentgenologic dynamics.

The content of general lipids, general phospholipids and their spectrum: lysophosphatidylcholine, phosphatidylcholine, sphingomyeline, phosphatidylethanolamine, phosphatidylserine, phosphatidylinositol, polyphosphatidic acids is determined in blood plasma and erythrocytic membranes in adult patients with various forms of stomatopharynx diphtheria. The dataindicating the changes of lipids components of blood plasma and erythrocytic membranes depending on the disease course gravity and conformation of erythrocytic membranes structure are obtained.

The possibilities of X-ray computer tomography in the diagnosis of endophitic tumors of the stomach including tumors of small sizes are considered using the examinations of 100 patients with stomach diseases. The computer—tomographic semiotics of small endophitic tumors of the stomach is presented, the place of computer tomography in the diagnisis о tumors of the stomach as well as its potential possibi lities in revealing small tumors of the stomach witl principally endophitic spreading.

The cases of difficult trachea intubation in the performance of general anesthesia are analyzed. Two aspects affecting the successful performance of intubation: the determination of the cause and degree of difficulty of the procedure involved and the choice of optimum method for it are provided.

As many as 65 patients with hematuria are examined by sonography at their receiving to the hospital in urgent conditions. The examinations are repeated in 2—4 days as well as conventional X-ray methods of examination. The sonography efficacy in the diagnosis of hematuria causes is shown in comparison with conventional X-ray methods.

The sinuses of regional lymphatic nodes obtained during operations of 50 oncologic patients are died using ultrastructural and morphometric method. The investigations are performed in 3 groups unow observation: 1) control (lymphatic nodes of practically healthy persons being lost from casual circumstances), 2) lymphatic nodes without metastases, 3) lymphatic nodes with metastases of various volume. It is established that the pronounced macrophagal and T-cellular reactions retard metastatic spreading in early stages of tumoral growth (I, II stade of cancer more rarely). The intensity of these reactions decreases noticeably providing holding in sinuses of malignant cells and generalization of tumoral process.

Unsatisfactory treatment results of malignant neoplasms in general and bladder cancer in particular require a closer study of their epidemiology. The incidence of bladder cancer varies from 1.3 to 6% among all malignant neoplasms of various localizations. According to autopsy findings, they comprise 35-50% of all tumors of urogenital organs and occur mostly in persons older than 40-45 years old. Men are affected 3-4 times more often than women.

To check HLA-association of myocardial infarction (MI) among citizens of Kazan, we profiled 32 patients (men) diagnosed with MI aged 33 to 58 years, 32 healthy blood transfusion station donors and medical personnel (also men) aged 32 to 56 years, who did not suffer from cardiovascular diseases at the time of examination.

Treatment of chronic gastroduodenal ulcers remains one of the most difficult and unsolved problems. The main difficulty that they try to overcome is their recurrent course. Nowadays the main directions of medical therapy of peptic ulcer disease are the decrease of intragastric acidity and sanation of gastroduodenal mucosa from Helicobacter Pylori. Treatment aimed at the destruction of Helicobacter Pylori allows to reduce the relapse rate to almost zero, provided it is successfully suppressed.

We analyzed the effectiveness of surgical laparoscopy in 107 patients with tubal-peritoneal form of infertility. The women were aged 20 to 25 years - 23 (21.5%), 26 to 35 - 68 (63.6%), 35 and over - 16 (14.9%). The duration of the sterility period varied from 1 to 5 years in 40 patients, from 6 to 9 years in 48 patients, from 10 to 14 years in 15 patients, and from 15 years or more in 4 patients.

Mimic tic refers to diseases whose pathogenesis may be due to a reflex mechanism. Its clinic is characterized by involuntary muscle twitches on one half of the face. As a rule, convulsions begin spontaneously, are easily provoked during eating, talking, mental and physical tension, appear only during the waking period and are completely painless. It affects people of different ages.

Early results of population sanitation in volunttary medical insurance system are presented. Its high efficacy in the context of revealing diseases in insured persons and appropriate treatment is shown.

The profound study of sickness rate and medical advice taking of population of Tatarstan Repute regions in treatment-and-prophylactic institutions allows to reveal the decrease of medical advice taking rate of east and south regions population (the regions over the Kama). The analysis of this phenomenon allows to formulate the conception of new medical devision into regions (zones) for medical service to rural population directed to availability increase and approaching of specialized medical service to rural population of the regions over the Kama.

The formation of roentgenology in Kazan is connected with the name of professor V.A. Luria, a therapeutic gastroenterologist. In 1922 he began to teach a course on roentgenology in the Institute for Advanced Training of Physicians, which he created. One of Luria's first students and organizer of the X-ray department of his clinic, which was later transformed into an independent department, was M.I. Goldstein (1896-1974).

The Congress was opened by the President of the All-Russian Scientific Society of Cardiology (ARSC) Prof. V.A. Lyusov (Moscow). He noted that for 4 years the society has completed re-registration according to the new charter and legal status and has 54 regional organizations in its membership. In 1993 at the XV Congress of the European Society of Cardiology the All-Russian Society of Cardiology was accepted as a permanent member with a casting vote. This membership will accelerate the international integration of cardiologists, without which the progress in the field of fundamental and applied research, training and expansion of international relations is unthinkable.