Vol 79, No 5 (1998)

Academician of the Russian Academy of Medical Sciences Andrey Dmitrievich Ado
Ishimova L.M.
Abstract

On October 26, 1997, Andrei Dmitrievich Ado, our Teacher in the best sense of the word, passed away. A true teacher is not one who teaches, but one from whom one can learn. One could learn a lot from Andrei Dmitrievich - as a scientist, teacher, thinker, philosopher, he willingly gave his knowledge, thoughts, ideas to everyone who wanted to find them.

Kazan medical journal. 1998;79(5):321-326
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Development, properties and clinical use of fungous allergens
Glushko N.I., Lukashkov V.M., Shakhbazov E.N., Shakhbazov E.N., Shaikhrazieva V.I.
Abstract

The diagnostic allergens from yeast-like and mold fungi of 18 names are developed and studied. The drugs are polysaccharide — protein complexes, they do not contain toxic components and conservants. They are used for the diagnosis of sensibilization in vivo and in vitro as well as for immunotherapy.

Kazan medical journal. 1998;79(5):327-333
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Development, properties and clinical use of fungous allergens
Khramov V.V., Burnasheva R.K., Fassakhov R.S.
Abstract

The diagnostic allergens from yeast-like and mold fungi of 18 names are developed and studied. The drugs are polysaccharide — protein complexes, they do not contain toxic components and conservants. They are used for the diagnosis of sensibilization in vivo and in vitro as well as for immunotherapy.

Kazan medical journal. 1998;79(5):334-338
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Incidence of bronchoobstructive syndrome in patients seeking phthisiopulmonologist
Wiesel A.A., Yaushev M.M., Khalfiev I.N.
Abstract

On the basis of examination of 5020 patients during 1991—1997 it is concluded that each third patient had bronchobstructive syndrome. If in disseminated and fibrocavernous tuberculosis the aggravation of bronchi permeability was found in each second patient, so in chronic obstructive bronchitis — in all patients. At the same time in sarcoidosis, in idiopathic fibrosing alveolitis this syndrome was rarely found. The analysis of 155 cases of the use of atrovent as an acute test with broncholithic showed the high efficiency of this cholinoblockator in significant obstruction and minimal effect in patients without ventilational insufficiency.

Kazan medical journal. 1998;79(5):339-342
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Use of flutikazone proponate in the treatment of patients with grave forms of bronchial asthma
Fassakhov R.S., Salieva E.V.
Abstract

The high efficiency of inhalation of one ofglucocorticosteroid hormones — flutikazone proponate is shown. The drug in the form of the dosed aerosol inhalator was successfully used in 24 patients with medium grave and grave course of the disease considering it as an alternative to the systemic use of glucocorticosteroids.

Kazan medical journal. 1998;79(5):343-345
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Peculiarities of the clinical course bronchial asthma in children
Tsybulkina V.N., Zainetdinova G.M., Shamsutdinova G.A., Salikhova A.N.
Abstract

It is established that in most of patients the course of atopic bronchial asthma occurs as clinical attacks of expiratory asphyxia repeated both by day and at night. In children aged 1 to 6 the course of this disease is principally slight, medium and grave. In elder age group (7—15 years) the share ef graver forms of bronchial asthma increases. The disease is determined by increased sensitivity to domestic allergens. Atypical forms are found only in young age group and obviously are not connected with hypersensitivity. The specific immunotherapy is an effective treatment method of the classical atopic bronchial asthma in children aged 7 to 15.

Kazan medical journal. 1998;79(5):346-348
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Use of ximedone in patients with pollinosis
Tsybulkin A.P., Khasanova M.I., Tsibulkina V.N.
Abstract

The efficiency of the home-made drug — ximedone in the treatment of patients with pollinosis used preseasonally and early in aggravation is studied. Its more pronounced preventive action in comparison with other variants of preseasonal treatment is established. It is effective in the period of pollinosis aggravation.

Kazan medical journal. 1998;79(5):349-353
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Effect of ximedone on the state of humoral antibacterial immunity in patients with angina
Zinkevich O.D., Kravchenko I.E., Fazylov V.K., Safina N.A., Platonov O.A., Urazaev R.A.
Abstract

The concentration of antibodies to antigens Streptococcus pyogenes, li posaccharide E of the salt 0 14, Pseudomonas aeruginosa, Proteus mirabilis, Staphylococcus aureus, Candida albicans, Streptococcus pneumoniae as well as to endotoxin (glycolipid RE 595 S.Minnesota) of Gram — negative flora in patients with angina in the treatment dynamics is determined by the hardphase immunofermental analysis method. The data obtained show the low concentration of antibodies to staphylococcus, endotoxin of Gram — negative flora, Candida and the high concentration — to Pseudomonas aeryginosa for the whole time of observation. The changes revealed show the dysbalance in specific humoral immunity in patients with angina. The new drug — ximedone normalizes the state of humoral antibacterial immunity in patients with angina.

Kazan medical journal. 1998;79(5):354-358
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Acute drug allergy in large industrial city
Reshetnikova I.D., Voitsekhovich G.S., Khramov V.V., Makarova L.V., Fassakhov P.S.
Abstract

The causes of drug allergy development are considered. The case records of patients entering the allergologie department of the city hospital № 7 for 5 years are analyzed. The tendency to more frequent anaphylactic shock cases as the gravest variety of drug allergy is noted. The necessity of anaphylactic shock prevention measures is stressed in which the most important ones are the detailed collection of allergologie anamnesis, the account of possible crossed reactions between drugs.

Kazan medical journal. 1998;79(5):359-362
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Formation of humoral immune response in atopic dermatitis in children
Agafonova E.V., Malanicheva T.G., Shamov B.A.
Abstract

The examination results of the humoral immune response in children with allergodermatosis and in healthy children of various age groups are presented. The following immune diagnosis methods are used: the determination of the basic class immunoglobulins content, complement activity and general Ig E level. The markers for the immune status estimation and atopic type response prediction taking into account the immune system ontogenesis are proposed.

Kazan medical journal. 1998;79(5):363-366
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Factors of eczema chronization in elder children
Shamova A.G., Shamov B.A., Malanicheva T.G.
Abstract

As many as 3000 children aged 12 to 18 living in the places with the established difference of qualitative and quantitative characteristics of atmospheric pollution are examined by the entire method. The incidence, age and sex structure of eczema depending on the degree of atmospheric pollution as well as the contribution of factors providing the chronic course of eczema are determined. Hereditary and constitutional peculiarities and digestion organs pathology have a significant effect. Nearly 20% of the contribution of factors are connected with prolonged unfavourable effect of enviropment — living conditions and atmospheric pollutants.

Kazan medical journal. 1998;79(5):367-329
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Riboxin in complex therapy in children with allergodermatoses
Malanicheva T.G., Shamova A.G., Shamov B.A.
Abstract

The use of riboxin in atopic dermatosis and urticaria allows to increase significantly the efficiency of the treatment: to decrease the acute period and hospitalization time of children as well as to increase the remission time. The use of riboxin is recommended in the treatment and rehabilitation of children with acute and chronic forms of allergodermatoses.

Kazan medical journal. 1998;79(5):370-372
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Microvesiculation in immunoconflict pregnancy and hemolytic disease of newborns
Subkhankulova А.F., Zubairov D.M., Subkhankulova F.B., Sadykov B.G.
Abstract

The microvesiculation process of cell membranes increases in blood of women during pregnancy development. In women with Rh-conflict pregnancy the course of the microvesiculation process is more intensive than in physiologic pregnancy. In intratubal affection of the fetus by hemolytic disease (the congenital icteric form) the microvesiculation process increases sharply in blood seram parallel to the increase of unconjugated bilirubin level. The determination of 5’-nucleotidase activity in hemolytic disease of newborns can be used as an additional diagnosis method of microvesiculation in this pathologic state.

Kazan medical journal. 1998;79(5):373-376
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Immunity indices in patients with late localized forms of postnatal infection
Gorin V.S., Semenkov N.N., Yasinskaya N.N., Renge L.V., Zhabin S.G.
Abstract

The state of cellular and humoral components of the immune system, phagocytic activity of peri pheric blood neutrophiles in 76 puerperas in late postnatal period is studied. The changes in the immune system response depending on the delivery method, the presence of postnatal complication as endometritis are revealed in puerperas with the complicated course of postnatal period. The pronounced changes in immune status confirming the developed second immunodeficiency accompanied by the gravest course of postnatal endometritis are revealed in puerperas with the complicated course of postoperative period.

Kazan medical journal. 1998;79(5):377-378
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About the role of antibodies formation in the decrease of therapeutic effect of captopril in patients with arterial hypertension
Tikhonov V.P., Ilyukhin O.V., Yakovlev A.T., Statsenko M.E., Kirakozov D.A., Popova A.S.
Abstract

Captopril being hapten is connected with blood serum albumin and is capable to induce antibodies elaboration. Captopril conjugate with bull serum albumin can be used as a specific diagnosticum for the hardphase immunofermental analysis. Specific immunoglobulins are one of the factors of the “escaping” effect development of the captopril hypotensive action.

Kazan medical journal. 1998;79(5):379-381
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Qualitative and quantitative cuanyes of lipids in experimental peritonitis
Trofimov V.A., Vlasov A.P., Minnebaev М.М.
Abstract

The considerable increase of the free fatty acids part, phospholipid lysophorms and the decrease of the main membrane lipids level are found in tissue lipids spectrum in peritonitis. The changes in organ li pids composition in many cases are correlated with those in blood plasma. Hence, the complex estimation of blood li pids is an adequate method of determining the biochemical lipid disorders intensity on the organ level.

Kazan medical journal. 1998;79(5):382-387
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Prospects for immunomodulatory therapy of bronchial asthma
Cherepnev G.V., Slabnov Y.D., Zimakova I.E.
Abstract

The relevance of pharmacological correction of immunological reactivity is obvious: many socially significant diseases are accompanied by an imbalance in immune homeostasis. In the past few years, a number of reviews on the classification and mechanisms of action of immunotropic drugs approved for clinical use in the Russian Federation have been published in the domestic press.

Kazan medical journal. 1998;79(5):388-391
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On the question of the treatment of urticaria
Burnyasheva R.K., Rakhmatullina N.M., Akhmetzyanova D.G., Zakirova G.N., Sibgatullina N.A., Salieva E.V.
Abstract

Urticaria is one of the most common diseases. All age groups are affected by this nosological form. Differences in etiological factors and body reactivity determine the variety of clinical forms of urticaria, the treatment of which requires a differentiated approach.

Kazan medical journal. 1998;79(5):392-393
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The defeat of the larynx with systemic lupus erythematosus
Alimetov K.A., Yakupova Z.N., Kislova V.M.
Abstract

The defeat of the cartilage and joints of the larynx in diffuse connective tissue diseases is extremely rare. M., 49 years old, was admitted to the ENT clinic on 02.11.1992 with complaints of shortness of breath. In this regard, in August 1992, she underwent a tracheostomy.

Kazan medical journal. 1998;79(5):393-393
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Experience of dispensary observation of patients with bronchial asthma
Gatupov R.R.
Abstract

The allergological service in the city of Nizhnekamsk has existed since 1982. The city is located in the zone of influence of a large petrochemical production, which leads to an increase in allergic and bronchopulmonary pathologies, including bronchial asthma of exo- and endogenous origin.

Kazan medical journal. 1998;79(5):394-396
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Automation of accounting and reporting in a children's clinic
Pigalov A.P., Ayupova A.Z., Gafarova R.K., Sherman T.M.
Abstract

Accounting and reporting are important sections of the work of any institution. Regardless of the type of activity, uniform requirements are imposed on them: timeliness, reliability and completeness of the initial data, prompt receipt of statistical results, the possibility of their comparison, registration of monetary costs and performance evaluation.

Kazan medical journal. 1998;79(5):396-397
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XIV International Congress "Modern Chemotherapy and Prevention of Tropical Malaria" (Nagasaki, November 17-22, 1996)
Popov A.F., Morokov V.S.
Abstract

Malaria is a serious problem in developing countries. Currently, mortality from it varies from 1.5 to 2.7 million people per year, and the incidence - from 300 to 500 million people annually. Social and economic losses in Africa alone are estimated at US $ 1.8 billion per year (Kondrashin, Traig, 1996).

Kazan medical journal. 1998;79(5):397-397
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Professor Ivan Fedorovich Kharitonov
Medvedev V.N.
Abstract

This year marks the 100th anniversary of the birth of the outstanding Kazan surgeon Ivan Fedorovich Kharitonov (09/20/1898 - 09/22/1985). Most of his life was associated with the surgical clinic named after A.V. Vishnevsky, in which he went from assistant to head of the department.

Kazan medical journal. 1998;79(5):398-399
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