Comparative analysis of physical development parameters of children with stages 1 to 3 of chronic kidney disease
- Authors: Nastausheva TL1, Zhdanova OA1, Nastausheva NS1, Stahurlova LI1, Grebennikova IV1
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Affiliations:
- Voronezh State Medical University named after N.N. Burdenko
- Issue: Vol 98, No 1 (2017)
- Pages: 5-9
- Section: Theoretical and clinical medicine
- URL: https://kazanmedjournal.ru/kazanmedj/article/view/6026
- DOI: https://doi.org/10.17750/KMJ2017-5
- ID: 6026
Cite item
Full Text
Abstract
Aim. To conduct comparative analysis of height, weight and body mass index in children with stages 1 to 3 of chronic kidney disease (CKD) caused by recurrent urinary tract infection due to congenital anomalies of kidney and urinary tract.
Methods. The study was performed on 210 children: 110 patients examined in 2001-2002 (group 1) and 100 children examined in 2011-2012 (group 2). Stage 1 of CKD was observed in 94 (85.4%) children in group 1 and in 93 (93%) in group 2, stage 2 - in 16 (14.6%) and 7 (7%) patients, respectively. From both groups patients matched by sex, age, diagnosis and social status were selected: 20 patients with stage 1, 19 children with stage 2; in addition, 6 children with stage 3 were examined.
Results. Nowadays children with CKD stage 1 are taller compared to patients of the beginning of the XXI century (Z-score: -0.14±1.43 and 0.20±0.98 respectively, p=0.01). Significant differences in weight were found in children with stage 1 in 2011-2012 compared to the patients in 2001-2002 (0.18±0.46 and 0.78±1.19 for groups 1 and 2, respectively, р=0.026). A tendency towards decrease of average height in children with stage 3 is observed compared to patients with stage 1, i.e. due to the progression of the disease.
Conclusion. The data obtained reflect modern tendencies towards increase of children height and weight. No significant differences were found in physical development parameters of children with stages of chronic kidney disease 1 and 2 examined at the same time period but a tendency towards children’s height decrease from stages 1 to 3 of CKD of non-glomerular etiology was revealed.
About the authors
T L Nastausheva
Voronezh State Medical University named after N.N. Burdenko
Author for correspondence.
Email: olga.vr9@yandex.ru
O A Zhdanova
Voronezh State Medical University named after N.N. Burdenko
Email: olga.vr9@yandex.ru
N S Nastausheva
Voronezh State Medical University named after N.N. Burdenko
Email: olga.vr9@yandex.ru
L I Stahurlova
Voronezh State Medical University named after N.N. Burdenko
Email: olga.vr9@yandex.ru
I V Grebennikova
Voronezh State Medical University named after N.N. Burdenko
Email: olga.vr9@yandex.ru
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