Kazan medical journalKazan medical journal0368-48142587-9359Eco-Vector602610.17750/KMJ2017-5Research ArticleComparative analysis of physical development parameters of children with stages 1 to 3 of chronic kidney diseaseNastaushevaT Lolga.vr9@yandex.ruZhdanovaO Aolga.vr9@yandex.ruNastaushevaN Solga.vr9@yandex.ruStahurlovaL Iolga.vr9@yandex.ruGrebennikovaI Volga.vr9@yandex.ruVoronezh State Medical University named after N.N. Burdenko150220179815920022017Copyright © 2017, Nastausheva T.L., Zhdanova O.A., Nastausheva N.S., Stahurlova L.I., Grebennikova I.V.2017<p><strong>Aim.</strong> To conduct comparative analysis of height, weight and body mass index in children with stages 1 to 3 of chronic kidney disease (CKD) caused by recurrent urinary tract infection due to congenital anomalies of kidney and urinary tract.</p><p><strong>Methods.</strong> The study was performed on 210 children: 110 patients examined in 2001-2002 (group 1) and 100 children examined in 2011-2012 (group 2). Stage 1 of CKD was observed in 94 (85.4%) children in group 1 and in 93 (93%) in group 2, stage 2 - in 16 (14.6%) and 7 (7%) patients, respectively. From both groups patients matched by sex, age, diagnosis and social status were selected: 20 patients with stage 1, 19 children with stage 2; in addition, 6 children with stage 3 were examined.</p><p><strong>Results.</strong> Nowadays children with CKD stage 1 are taller compared to patients of the beginning of the XXI century (Z-score: -0.14±1.43 and 0.20±0.98 respectively, p=0.01). Significant differences in weight were found in children with stage 1 in 2011-2012 compared to the patients in 2001-2002 (0.18±0.46 and 0.78±1.19 for groups 1 and 2, respectively, р=0.026). A tendency towards decrease of average height in children with stage 3 is observed compared to patients with stage 1, i.e. due to the progression of the disease.</p><p><strong>Conclusion.</strong> The data obtained reflect modern tendencies towards increase of children height and weight. No significant differences were found in physical development parameters of children with stages of chronic kidney disease 1 and 2 examined at the same time period but a tendency towards children’s height decrease from stages 1 to 3 of CKD of non-glomerular etiology was revealed.</p>chronic kidney diseasechildrenbody heightbody weightbody mass indexphysical developmentхроническая болезнь почекдетидлина теламасса телаиндекс массы телафизическое развитие[Конь И.Я., Волкова Л.Ю., Коростелева М.М. и др. Распространённость ожирения у детей дошкольного и школьного возраста в Российской Федерации. Вопр. детской диетол. 2011; 9 (4): 5-8.][Молчанова М.С., Петросян Э.К., Казымова С.Э., Молчанова Е.А. 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