Vol 63, No 5 (1982)

Dimexide was used in a complex of intensive care in 42 extremely severe patients with septic complications of postresuscitation disease. The drug was administered intravenously, for drainage and in combination: in combination with infusion-transfusion, anticoagulant and antibiotic therapy. The observation results show that Dimexide is an effective remedy for the correction and prevention of septic complications of postresuscitation disease, even with resistance to antibiotics.

The results of the determination of soluble fibrin-monomer complexes according to the data of paracoagulation tests in patients with acute myocardial infarction treated with heparin at various doses are presented. With negative results of paracoagulation tests, heparin therapy at a dose of 10 thousand units per day can effectively prevent the development of thrombotic complications. With positive results of these tests, the appointment of heparin only in a dose of 50-60 thousand units. per day contributes to the effective prevention of thrombotic complications.

Objective and subjective diagnostic, treatment-tactical, organizational errors in the management of patients with acute pneumonia have been studied. The quantitative and qualitative characteristics of mistakes at all stages of rehabilitation are given. The greatest number of medical miscalculations was observed at the pre-hospital stage.

With the help of rheoencephalography, echoencephalography, and rheoaurography, 216 patients with chronic purulent otitis media were examined. In patients with chronic purulent epitympanitis and epimesotympanitis, hemodynamic disturbances were revealed during rheoaurography. Hydrocephalic-hyperhydration syndrome was noted rheoencephalographically in local leads in 73% of patients in this group. Echoencephalography showed signs of hydrocephalus in 56% of patients. The complex application of rheoencephalography and echoencephalography made it possible to establish signs characteristic of the initial, clinical forms of otogenic intracranial complications.

A method for direct endoscopy of the pancreas and omental bursa has been developed. 26 out of 35 patients with pancreatitis were able to examine and carry out therapeutic measures using this method.

Based on the experience of diagnosis and treatment of post-transfusion acute renal failure in 27 surgical patients, the tactics, role and place of hemodialysis in complex therapy are considered. Outcomes and ways to improve treatment outcomes are reported.

Specific hyposensitization with bacterial allergens was carried out in 406 patients with infectious-allergic diseases (pre-asthma, and infectious-allergic forms of bronchial asthma, rhinitis, urticaria). The overall positive result of hyposensitization was 72.7%.

The indices of humoral and cellular immunity were studied in 10 patients with typical and 7 atypical (carriage) forms of diphtheria infection. The highest level of antibodies (4.25 ± 1.2 AU / ml) was in carriers of diphtheria bacteria, and the lowest (0.07 AU / ml) was in patients with toxic diphtheria. Disturbances in the structure of cellular immunogomeostasis - a decrease in the total number of T-lymphocytes, an increase in Ta-ROK, an increase in the functional activity of phagocytic neutrophils and peripheral blood monocytes - were found in all and were most pronounced in patients with toxic diphtheria. In children, according to epidemiological indications, vaccinated with ADS, while the number of T-lymphocytes was preserved, all other studied parameters turned out to be increased.

For the diagnosis and treatment of neurodermatitis with bacterial sensitization in children, purified bacterial allergens of Staphylococcus aureus, Streptococcus pyogenic and Escherichia coli were used. Specific immunotherapy was administered to 99 patients. Good and excellent results were obtained in 76.8% of patients, satisfactory - in 12%, unsatisfactory - in 11.1% of children. The clinical effect was accompanied by a decrease in body sensitization indices and activation of the humoral-cellular link of immunity.

In 120 patients with chronic bronchitis and 104 healthy individuals, circulating autoantibodies to the bronchial mucosa were studied. Exacerbation of the chronic inflammatory process in the bronchi is accompanied by a significant increase in autoantibody titers. A direct relationship was found between the level of autoantibodies, the severity and duration of the disease. By the time of discharge from the hospital in some patients, autoantibody titers remain at a high level, often up to six months. Determination of anti-bronchial antibodies in the dynamics of chronic bronchitis can be used to recognize the activity of the inflammatory process and predict its outcome.

In 22 patients with leukoplakia and kraurosis of the vulva, acupuncture was performed, which turned out to be an effective method of treating this pathology. Changes in the vulva disappeared after the second course of treatment, and with widespread prodesss - after the third.

On the pages of the Kazan Medical Journal, the issues of the classification of chronic pneumonia are again discussed as a discussion. It should be emphasized that the proposed classifications do not relate to chronic pneumonia in a collective sense, as envisaged by the Minsk (1964) and Tbilisi (1972) classifications, which have been seriously criticized. We are talking about chronic pneumonia, as a strictly localized recurrent inflammatory process in the bronchopulmonary system, characterized not only by localization (in a lobe or segment), but also by variants of the course (rare or frequent exacerbations, continuously recurrent course), the phase of the pathological process (exacerbation, remission) , the degree of disease activity in the exacerbation phase (pronounced or moderate exacerbation, sluggish process).

Cardiac glycosides (CG) attracted the attention of scientists at the turn of the 18th-19th centuries. The first clinical lecture on digitalis treatment belongs to S.P.Botkin. However, from the very beginning of the study of cardiac glycosides, it was noted that their excellent therapeutic effect is often combined with severe adverse reactions. Sometimes an incorrect interpretation of the therapeutic and toxic effects of SG (for example, with angina pectoris) led to unreasonable contraindications.

In the structure of morbidity among workers in contact with cutting fluids, the largest specific weight was occupied by diseases of the ENT organs. The second most frequent place was occupied by autonomic dysfunctions, often occurring with hypertensive type of neurocirculatory dystonia. For the prevention of these diseases, a complex of health-improving measures has been developed.

While still a student, in 1915 Nikolai Nikolaevich Sirotinin began working in the field of bacteriology at the Saratov Veterinary Institute, and from 1917 at the Department of Microbiology at Saratov University. Later (1919-1923) he continued to work on bacteriology in various microbiological institutions in Saratov, starting from the position of a laboratory assistant. Nikolai Nikolayevich instilled this style of training a scientist in his students. He demanded that each employee of the laboratory begin his activity with the rough work of a minister and a laboratory assistant, and only after that would he admit him to independent scientific research.