Kazan medical journalKazan medical journal0368-48142587-9359Eco-Vector6451910.17816/kazmj64519Research ArticleFeatures of immunity in patients with diphtheriaLebenzonS. S.info@eco-vector.comMayanskyD. N.info@eco-vector.comSpiridonovaE. A.info@eco-vector.comVasyuninA. V.info@eco-vector.comAltukhovaI. V.info@eco-vector.comGarbuzovaS. B.info@eco-vector.comNovosibirsk Medical InstituteInstitute of Clinical and Experimental Medicine, Siberian Branch of the USSR Academy of Medical Sciences1510198263541420204202102042021Copyright © 1982, Lebenzon S.S., Mayansky D.N., Spiridonova E.A., Vasyunin A.V., Altukhova I.V., Garbuzova S.B.1982<p><span class="VIiyi" lang="en"><span class="JLqJ4b" data-language-for-alternatives="en" data-language-to-translate-into="ru" data-phrase-index="0">The indices of humoral and cellular immunity were studied in 10 patients with typical and 7 atypical (carriage) forms of diphtheria infection. The highest level of antibodies (4.25 1.2 AU / ml) was in carriers of diphtheria bacteria, and the lowest (0.07 AU / ml) was in patients with toxic diphtheria. Disturbances in the structure of cellular immunogomeostasis - a decrease in the total number of T-lymphocytes, an increase in Ta-ROK, an increase in the functional activity of phagocytic neutrophils and peripheral blood monocytes - were found in all and were most pronounced in patients with toxic diphtheria. In children, according to epidemiological indications, vaccinated with ADS, while the number of T-lymphocytes was preserved, all other studied parameters turned out to be increased.</span></span></p>diphtheria infectionimmunogomeostasisphagocytic neutrophils and monocytesKazan Medical archivдифтерийная инфекцияиммуногомеостазфагоцитирующие нейтрофилы и моноцитыКазанский медицинский архив[Покровский В. И., Авербах М. М„ Литвинов В. И., Рубцов И. В. Приобретенный иммунитет и инфекционный процесс. М., Медицина, 1979.]