Textural characteristics of subchondral bone in osteoarthritis
- Authors: Kabalyk MA1
-
Affiliations:
- Pacific State Medical University
- Issue: Vol 97, No 4 (2016)
- Pages: 518-523
- Section: Theoretical and clinical medicine
- Submitted: 18.11.2016
- Published: 15.08.2016
- URL: https://kazanmedjournal.ru/kazanmedj/article/view/5595
- DOI: https://doi.org/10.17750/KMJ2016-518
- ID: 5595
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Abstract
Aim. To assess the relationship between textural characteristics of the subchondral bone and standard X-ray data, to determine markers of subchondral bone remodeling in gonarthrosis.
Methods. The studied group included 92 patients aged 66.1±10.5 years with I-IV grades osteoarthritis by the Kellgren, in the comparison group - 24 volunteers aged 29.6±5.96 years without clinical or radiological signs of gonarthrosis. Standard digital X-ray of the knee joint was performed. On the image, the area of interest was chosen, including a portion of the subchondral bone of 48±2×90±4 pixels of size. According to the area texture, the gray-level histogram and 3D graph of the pixels intensity distribution in area were made.
Results. The distribution of individual pixel values relating to the average gray-level values showed an inverse correlation with the disease stage (r=-0.52, p=0.00004) and the presence of large osteophytes (r=-0.40, p=0.002). Extremum of 3D histogram minimum value directly correlated with radiographic stage of gonarthrosis (r=0.42, p=0.0009), patients’ age (r=0.33, p=0.01) and the osteophytes number (r=0.43, p=0.0007). This figure was higher in the group of patients with osteoarthritis (p=0.009) and significantly decreased with the disease progression (p=0.04).
Conclusion. For the first time the analysis of 3D surface reconstruction depending on the gray-level pixel values was used, which showed good characteristics on the distinguishing groups of patients with osteoarthritis, and comparability with standard radiographic protocol data; the best results demonstrated the minimum value at 3D histogram that had significant variation depending on the disease stage.
Keywords
About the authors
M A Kabalyk
Pacific State Medical University
Author for correspondence.
Email: Maxi_maxim@mail.ru
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