Development of new ways of operative interventions on the submucosal membranes of the stomach

At the present time in the treatment of peptic ulcer disease of the stomach and duodenum the pyloroanthral gastric demucosalization is applied. Reduction of secret-producing function of the stomach is also achieved in case of small curvature zone demucosalization with subsequent suturing of mucosal defect. Although subtotal mucosectomy is accompanied by persistent decrease in hydrochloric acid secretion, however it has not found clinical application due to its traumatic and unphysiological character. It should be noted that gastric demucosalization is not without its negative sides: it is not aseptic, because the lumen of the stomach is opened; it is associated with difficulties of suturing the gastric mucosa; there is also a risk of bleeding from the submucosa in extensive mucosectomies. The aim of our research was the experimental development of new methods of surgical interventions on the stomach by resection of its submucous-mucous membranes with preservation of serous-muscular membranes, pyloric jejunum and structures innervating them.