Immunotherapy with bacterial allergens for recurrent aphthous stomatitis

Abstract

The examination of 53 patients with chronic recurrent aphthous stomatitis revealed bacterial sensitization in the majority of them, especially often to allergens of Staphylococcus aureus, Streptococcus pyogenes and E. coli. In 4 cases, skin reactions to bacterial allergens were weakly positive or negative. Quite often the patients were found to be polyvalent sensitized: 35 patients were sensitized to 2 different allergens, and 5 patients were sensitized to 3.