A rare clinical case of Lemierre’s syndrome

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Abstract

Lemierre's syndrome is a clinical variant of sepsis characterized by a combination of an infectious process in the oropharynx with thrombosis of the internal jugular vein and metastatic septic foci. Currently, Lemierre's syndrome is a rare pathology, almost a “forgotten disease”. The article describes a case of Lemierre's syndrome, in which the course of acute tonsillopharyngitis in a 20-year-old female patient was complicated by thrombosis of the left internal jugular vein and metastasis of septic foci in the lungs. The process was accompanied by a systemic inflammatory reaction and thrombocytopenia. The microorganism from the blood was not isolated. In crops from the oropharynx, Klebsiella pneumonia was found. The treatment included antibiotic therapy with ceftriaxone and azithromycin, the administration of glucose-salt solutions, the use of anticoagulants, and local antiseptic treatment of the oral cavity. Body temperature returned to normal on the 3rd day of hospitalization, inflammatory changes were jugulated after 9 days. The patient was discharged home on the 12th day of hospitalization in a satisfactory condition. Lemierre's syndrome is still a life-threatening condition, no matter how or by what it was caused. For this reason, early diagnosis and antibiotic therapy are critical to a favorable outcome of the syndrome.

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About the authors

Khalit S. Khaertynov

Kazan State Medical University

Author for correspondence.
Email: khalit65@yandex.ru
ORCID iD: 0000-0002-9013-4402

M.D., Cand. Sci. (Med.), Assoc. Prof., Depart. of Children's Infections

Russian Federation, Kazan, Russia

Vladimir A. Anokhin

Kazan State Medical University

Email: anokhin56@mail.ru
ORCID iD: 0000-0003-1050-9081

M.D., D. Sci. (Med.,), Prof., Head, Depart. of Children's Infections

Russian Federation, Kazan, Russia

Irina V. Nikolaeva

Kazan State Medical University

Email: irinanicolaeva@mail.ru
ORCID iD: 0000-0002-6646-302X

M.D., D. Sci. (Med.,), Prof., Head, Depart. of Infectious Diseases

Russian Federation, Kazan, Russia

Zulfiya L. Khamidullina

Republican Clinical Infectious Diseases Hospital named after A.F. Agafonov

Email: khamidullinaZulfiya@mail.ru
ORCID iD: 0000-0002-9056-8964

M.D., Head of the department

Russian Federation, Kazan, Russia

Ilseyar R. Idrisova

Republican Clinical Infectious Diseases Hospital named after A.F. Agafonov

Email: ikvadrate@mail.ru
ORCID iD: 0000-0002-9305-4950

M.D.

Russian Federation, Kazan, Russia

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Supplementary files

Supplementary Files
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1. Рис. 1. Ультразвуковое исследование левой внутренней яремной вены (поперечный срез). Визуализируются тромботические массы

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2. Рис. 2. Ультразвуковое исследование левой внутренней яремной вены (продольный срез). Визуализируются тромботические массы

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3. Рис. 3. Компьютерная томография органов грудной клетки. Визуализируются очаги инфильтрации лёгочной ткани

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