A rare clinical case of Lemierre’s syndrome
- Authors: Khaertynov K.S.1, Anokhin V.A.1, Nikolaeva I.V.1, Khamidullina Z.L.2, Idrisova I.R.2
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Affiliations:
- Kazan State Medical University
- Republican Clinical Infectious Diseases Hospital named after A.F. Agafonov
- Issue: Vol 103, No 3 (2022)
- Pages: 504-508
- Section: Clinical observations
- URL: https://kazanmedjournal.ru/kazanmedj/article/view/90264
- DOI: https://doi.org/10.17816/KMJ2022-504
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Abstract
Lemierre's syndrome is a clinical variant of sepsis characterized by a combination of an infectious process in the oropharynx with thrombosis of the internal jugular vein and metastatic septic foci. Currently, Lemierre's syndrome is a rare pathology, almost a “forgotten disease”. The article describes a case of Lemierre's syndrome, in which the course of acute tonsillopharyngitis in a 20-year-old female patient was complicated by thrombosis of the left internal jugular vein and metastasis of septic foci in the lungs. The process was accompanied by a systemic inflammatory reaction and thrombocytopenia. The microorganism from the blood was not isolated. In crops from the oropharynx, Klebsiella pneumonia was found. The treatment included antibiotic therapy with ceftriaxone and azithromycin, the administration of glucose-salt solutions, the use of anticoagulants, and local antiseptic treatment of the oral cavity. Body temperature returned to normal on the 3rd day of hospitalization, inflammatory changes were jugulated after 9 days. The patient was discharged home on the 12th day of hospitalization in a satisfactory condition. Lemierre's syndrome is still a life-threatening condition, no matter how or by what it was caused. For this reason, early diagnosis and antibiotic therapy are critical to a favorable outcome of the syndrome.
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About the authors
Khalit S. Khaertynov
Kazan State Medical University
Author for correspondence.
Email: khalit65@yandex.ru
ORCID iD: 0000-0002-9013-4402
M.D., Cand. Sci. (Med.), Assoc. Prof., Depart. of Children's Infections
Russian Federation, Kazan, RussiaVladimir A. Anokhin
Kazan State Medical University
Email: anokhin56@mail.ru
ORCID iD: 0000-0003-1050-9081
M.D., D. Sci. (Med.,), Prof., Head, Depart. of Children's Infections
Russian Federation, Kazan, RussiaIrina V. Nikolaeva
Kazan State Medical University
Email: irinanicolaeva@mail.ru
ORCID iD: 0000-0002-6646-302X
M.D., D. Sci. (Med.,), Prof., Head, Depart. of Infectious Diseases
Russian Federation, Kazan, RussiaZulfiya L. Khamidullina
Republican Clinical Infectious Diseases Hospital named after A.F. Agafonov
Email: khamidullinaZulfiya@mail.ru
ORCID iD: 0000-0002-9056-8964
M.D., Head of the department
Russian Federation, Kazan, RussiaIlseyar R. Idrisova
Republican Clinical Infectious Diseases Hospital named after A.F. Agafonov
Email: ikvadrate@mail.ru
ORCID iD: 0000-0002-9305-4950
M.D.
Russian Federation, Kazan, RussiaReferences
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