The effect of semipermeable membranes on the contact activation of blood clotting during programmed hemodialysis

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Abstract

Currently, hemodialysis is one of the effective methods of treatment of end-stage chronic renal failure (CRF). As is known, with this method of purification, the patient's blood comes into direct contact with a semipermeable membrane over a large area, through which nitrogenous slags are removed from the body. Despite the fact that in order to prevent blood clotting in the extracorporeal system, its heparinization is carried out, sometimes there is thrombosis of the dialyzer and its highways. A similar complication was observed by M. D. Javad-Zade and P. S. Malkov (1978) in 1% of cases, and I. S. Yarmolinsky and X. K. Chernevskis (1978) - in 2.5%. In this regard, all new membranes created for hemodialysis need to be studied by their interaction with blood.

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About the authors

S. A. Mukhametzyanov

Kazan State Medical University named after V. I. Lenin; Central Research Institute of the Kazan Order of the Red Banner of Labor Medical Institute named after S. V. Kurashov; All-Union Research Institute of Medical Polymers

Author for correspondence.
Email: info@eco-vector.com

Department of Urology

Russian Federation, Kazan; Kazan

B. S. Eltsephon

Kazan State Medical University named after V. I. Lenin; Central Research Institute of the Kazan Order of the Red Banner of Labor Medical Institute named after S. V. Kurashov; All-Union Research Institute of Medical Polymers

Email: info@eco-vector.com

Department of Urology

Russian Federation, Kazan; Kazan

L. G. Popova

Kazan State Medical University named after V. I. Lenin; Central Research Institute of the Kazan Order of the Red Banner of Labor Medical Institute named after S. V. Kurashov; All-Union Research Institute of Medical Polymers

Email: info@eco-vector.com

Department of Urology

Russian Federation, Kazan; Kazan

V. A. Gaponenko

Kazan State Medical University named after V. I. Lenin; Central Research Institute of the Kazan Order of the Red Banner of Labor Medical Institute named after S. V. Kurashov; All-Union Research Institute of Medical Polymers

Email: info@eco-vector.com

Department of Urology

Russian Federation, Kazan; Kazan

T. P. Ruban

Kazan State Medical University named after V. I. Lenin; Central Research Institute of the Kazan Order of the Red Banner of Labor Medical Institute named after S. V. Kurashov; All-Union Research Institute of Medical Polymers

Email: info@eco-vector.com

Department of Urology

Russian Federation, Kazan; Kazan

M. X. Vakhitova

Kazan State Medical University named after V. I. Lenin; Central Research Institute of the Kazan Order of the Red Banner of Labor Medical Institute named after S. V. Kurashov; All-Union Research Institute of Medical Polymers

Email: info@eco-vector.com

Department of Urology

Russian Federation, Kazan; Kazan

N. A. Vengerova

Kazan State Medical University named after V. I. Lenin; Central Research Institute of the Kazan Order of the Red Banner of Labor Medical Institute named after S. V. Kurashov; All-Union Research Institute of Medical Polymers

Email: info@eco-vector.com

Department of Urology

Russian Federation, Kazan; Kazan

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© 1983 Eco-Vector





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