On the mechanism of the vasodilatatory effect of stimulation of the antidromic nerves

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Blood, taken from the vein of the hind leg during stimulation of the posterior roots of the last two lumbalic and the first sacral nerves gives a marked dilatating effect on the blood-vessels of an isolated rabbit ear; when perfusing the ear the blood was diluted 1:100 with Ringer-solution.

The same effect is given by Ringer-solution, perfused through the vessels of the hind extremity during the stimulation of the correspon ding nerve-roots.

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A. W. Kibjakow

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Email: info@eco-vector.com

physiological laboratory

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2. Fig. No. 1

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3. Curve 2 ( н nat. vel.). Blood pressure curve: 1 with the introduction of 10 tbsp.3 of blood taken from another animal before the irritation of the roots, a gradual slight increase in blood pressure is noticeable. At the bottom is the mark of the beginning and end of the blood infusion, as in the following curves.

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4. Curve 3 (½ nat. vel.). Blood pressure curve. At the bottom is the same mark as on curve No. 2. With the introduction of blood taken from another animal, but already during the irritation of the posterior roots, a decrease in pressure is caused, and then its gradual leveling.

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5. Curve. 4. The same experience. With the introduction of 10 tbsp.3 of blood taken after irritation, it is visible on a weak gradual rise in blood pressure, pronounced Traub e-Negipdwaves.

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6. Curve. 5. The same experience, but in an animal to which blood is injected, the spinal cord is cut between the 2nd - 3rd cervical vertebra. With the infusion of 10 tbsp.3 of blood taken during the irritation of the roots, there is a noticeable decrease in blood pressure with a very gradual leveling out. Kimograph stop—3 minutes.

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7. Fig. 6. Recording drops in experiment No. 14. The upper line is the effect of irritation of the dorsal roots, the next line is the mark of the expansion of the roots, below is the time in 1'. The lower line is the passage of fluid obtained during the irritation of the roots from the first drug. X is the beginning of the passage of this liquid, which replaced the liquid obtained before irritation.

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