Complication of giardiasis treatment with osarsol

Osarsol is a complex organic compound of arsenic (para-oxy-acetamido-phenyl-arsinic acid), synthetically obtained by Gosmedtorgprom in 1924 and commercialized in tablets of 0.25 g for internal administration as an antisyphilitic agent. Doses for adults, according to the instructions I osmedtorgproma, 0.5-1.0 per day with intervals of 3-5 days after taking every 5 g osarsol, in total for a course of treatment for syphilis is given 25-30 g of the drug. In addition to syphilis, Osarsol is used in worm infestations, in protozoan-trypanosomal diseases and in spirillosis. The literature shows that osarsol, as well as its analogues, together with salvarsan, proposed by Yakimov for the treatment of giardiasis as early as in 1917, proved to be an effective remedy for giardiasis (Chapurskaya-Bazhenova, Georgievskaya, Volodin, Limcher and Traikina, Filipchenko, etc.). This drug has been widely used in recent years in Giardia infestations.