Problems and prospects of studying hemorrhagic fever with renal syndrome in the Republic of Tatarstan
- Authors: Boyko VA1, Savitskaya TA1, Trifonov VA1,2, Serova IV1, Isaeva GS.1,3
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Affiliations:
- Kazan Scientific Research Institute of Epidemiology and Microbiology
- Kazan State Medical Academy
- Kazan State Medical University
- Issue: Vol 101, No 5 (2020)
- Pages: 775-785
- Section: History of medicine
- URL: https://kazanmedjournal.ru/kazanmedj/article/view/33845
- DOI: https://doi.org/10.17816/KMJ2020-775
- ID: 33845
Cite item
Abstract
The paper presents the history of the study of hemorrhagic fever with renal syndrome (HFRS) at the Kazan Research Institute of Epidemiology and Microbiology from the beginning of the 50s to the present. The accumulated information allows to draw up general conceptions about the main source of infection, the biological structure of natural foci of infection, nosoarea and the main clinical forms of the disease, the nature and seasonality of the disease, the sex and age composition of patients, and the types of natural foci of HFRS. The stages of improving the methods of laboratory diagnosis of HFRS, development of a specific immunoglobulin against the serum of the Puumala virus are described. A significant contribution to the study of HFRS was the landscape-epidemiological ranking of the territory of the Republic of Tatarstan and the Middle Volga endemic for HFRS, with the identification of zones of special risk of human infection and the main factors that form them. At present, a reference center for monitoring HFRS has been created based on the Kazan Research Institute of Epidemiology and Microbiology, and the study of the properties of HFRS pathogens at the current molecular-genetic level continues.
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About the authors
V A Boyko
Kazan Scientific Research Institute of Epidemiology and Microbiology
Email: tatasav777@mail.ru
Russian Federation, Kazan, Russia
T A Savitskaya
Kazan Scientific Research Institute of Epidemiology and Microbiology
Author for correspondence.
Email: tatasav777@mail.ru
Russian Federation, Kazan, Russia
V A Trifonov
Kazan Scientific Research Institute of Epidemiology and Microbiology; Kazan State Medical Academy
Email: tatasav777@mail.ru
Russian Federation, Kazan, Russia; Kazan, Russia
I V Serova
Kazan Scientific Research Institute of Epidemiology and Microbiology
Email: tatasav777@mail.ru
Russian Federation, Kazan, Russia
G Sh Isaeva
Kazan Scientific Research Institute of Epidemiology and Microbiology; Kazan State Medical University
Email: tatasav777@mail.ru
Russian Federation, Kazan, Russia; Kazan, Russia
References
- Ткаченко Е.А., Ишмухаметов А.А. История изучения этиологии геморрагической лихорадки с почечным синдромом. Мед. совет. 2017; (4): 86–92. [Tkachenko E.A., Ishmukhametov A.A. History of the study of hemorrhagic fever etiology with renal syndrome. Meditsinskiy sovet. 2017; (4): 86–92. (In Russ.)] doi: 10.21518/2079-701X-2017-4-86-92.
- Churilov A.V. Clinic of the so-called nephroso-nephritis. Klinicheskaya meditsina. 1941; (8): 78–82. (In Russ.)
- Kazbintsev L.I. Clinic of the so-called acute infectious nephritis. Terapevticheskiy arkhiv. 1941; (3): 341–346. (In Russ.)
- Dunaevskiy M.I. The problem of hemorrhagic nephroso-nephritis. Report 2. Changes in blood and urine in hemorrhagic nephrosis-nephritis and their importance for diagnosis and pathogenesis. Arkhiv biologicheskikh nauk. 1941; 62 (5): 53. (In Russ.)
- Smorodintsev A.A., Al'tshuller I.S., Dunaevskiy M.I. et al. Etiologiya i klinika gemorragicheskogo nefrozo-nefrita. (Etiology and clinic of hemorrhagic nephroso-nephritis.) М.: Medgiz. 1944; 47 р. (In Russ.)
- Kitano M. Purpura haemorrhagica epidemica. J. Orient. Med. 1940; Febr.: 192–209.
- Vereta L.A., Vladimirova T.P., Koval'skiy G.K. Experience in specific prevention of HFRS. Zhurnal mikrobiologii. 1968; (5): 3–8. (In Russ.)
- Bojko V.A., Trifonov V.A., Potapov V.S. Prirodnye ochagi zooantroponozov transformirovannyh landshaftov Respubliki Tatarstan vo vtoroj polovine XX veka. (Natural foci of zooanthroponoses in the transformed landscapes of the Republic of Tatarstan in the second half of the 20th century.) Kazan': Novoe znanie. 2001; 120 р. (In Russ.)
- Gemorragicheskaya lihoradka s pochechnym sindromom (GLPS) v Srednem Povolzh'e i Predural'e. (Hemorrhagic fever with renal syndrome (HFRS) in the Middle Volga region and the Urals.) Leningrad. 1980; 135 р. (In Russ.)
- Lee H.W., Lee P.W., Johnson K.M. Isolation of the etiologic agent of Korean hemorrhagic fever. J. Infect. Dis. 1978; 137: 298–308. doi: 10.1093/infdis/137.3.298.
- Part 1. Etiology, laboratory diagnostics, epidemiology, prevention. In: Gemorragicheskaya lihoradka s pochechnym sindromom (GLPS) v Srednem Povolzh'e. (Hemorrhagic fever with renal syndrome (HFRS) in the Middle Volga region.) Kazan': KIB KFAN SSSR. 1989; 128 р. (In Russ.)
- Boyko V.A., Trifonov V.A., Potapov V.S. Prirodno-ochagovye infekcii v lesah goroda Kazani i Prikazanskogo regiona. (Natural focal infections in the forests of the city of Kazan and the Prikazan region.) Kazan': Medicina. 2011; 110 р. (In Russ.)
- Boyko V.A., Trifonov V.A., Reshetnikova I.D. Monitoring dominiruyushchih prirodno-ochagovyh infekcij i opyt ocenki potencial'nogo riska zarazheniya naseleniya v landshaftnyh podzonah Tatarstana. (Monitoring of dominant natural focal infections and experience in assessing the potential risk of infection of the population in the landscape subzones of Tatarstan.) Kazan'. 2017; 83 р. (In Russ.)
- Savitskaya T.A., Trifonov V.A., Agafonova E.V. et al. Serological monitoring in the epidemiological surveillance system of feral herd infections in the Republic of Tatarstan. Epidemiologiya i infektsionnye bolezni. Aktual'nye voprosy. 2018; (1): 15–20. (In Russ.)
- Povalishina T.P., Dzagurov S.G., Yankovskiy A.K. Epidemiological characteristics of foci of hemorrhagic fever with renal syndrome (HFRS) in the European part of the RSFSR. Materialy. problemnoy komissii IPiVE AMN SSSR. 1967; 2: 195–197. (In Russ.)
- Savel'eva N.A., Vostrikov L.A. Some issues of the epidemiology of hemorrhagic fever with renal syndrome in the Khabarovsk Krai and the tactics of preventive measures. Trudy IPiVE AMN SSSR. 1965; 7: 95–96. (In Russ.)
- Simonov S.B., Slonova R.A., Simonov P.S. Ecologo-epidemiological zoning of Primorye region in connection with hantavirus infection. Vestnik DVO RAN. 2008; (3): 58–64. (In Russ.)
- Ermolaev O.P., Igonin M.E., Bubnov A.Yu., Pavlova S.V. Landshafty Respubliki Tatarstan. Kazan': Slovo. 2007; 410 р. (In Russ.)
- Trifonov V.A., Davidyuk Yu.N., Isaeva G.Sh. et al. Study of the infection of the red vole by the Puumala virus in natural foci of HFRS in Tatarstan. Dnevnik Kazanskoy meditsinskoy shkoly. 2018; (4): 36–39. (In Russ.)
- Trifonov V.A., Boiko V.A., Savitskaya T.A. Methodological approaches to monitoring of the population morbidity with natural focal infections in large cities of the Republic of Tatarstan. Meditsinskiy al'manakh. 2017; (4): 102–106. (In Russ.)
- Savitskaya T.A., Trifonov V.A., Isaeva G.Sh. et al. Review of the current epidemiological situation on the incidence of hemorrhagic fever with renal syndrome in the world and forecast of the incidence for the territory of the Russian Federation in 2019. Problemy osobo opasnyh infektsiy. 2019; (2): 30–36. (In Russ.) doi: 10.21055/0370-1069-2019-2-30-36.