Influence of nutritional status and body mass index of patients on the prognosis and course of chronic obstructive pulmonary disease
- Authors: Prokonich D.A.1, Saprina T.V.1, Bukreeva E.B.1, Sadovnikova A.Y.1, Chuprunova A.K.1
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Affiliations:
- Siberian State Medical University
- Issue: Vol 104, No 4 (2023)
- Pages: 590-603
- Section: Reviews
- URL: https://kazanmedjournal.ru/kazanmedj/article/view/112434
- DOI: https://doi.org/10.17816/KMJ112434
- ID: 112434
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Abstract
The problem of the relationship of nutritional status with the risk of development, course features and prognosis of chronic obstructive pulmonary disease is of considerable scientific and practical interest, but remains poorly understood. However, in clinical practice, it is customary to calculate only the body mass index, but this indicator cannot provide a complete characterization of the nutritional status. We have reviewed the data of publications indicating the conditionality of the course of chronic obstructive pulmonary disease by the value of the body mass index, the amount of muscle mass of the body and such parameters of adipose tissue as its distribution in the body, hormonal activity and production of systemic chronic inflammation markers. To assess the dynamics of body mass index and spirometric parameters in patients with chronic obstructive pulmonary disease, 76 publications that were selected by the keywords “COPD”, “BMI” in the Scopus, PubMed, eLibrary databases for 1995–2022, were analyzed. Correlation analysis was carried out using Spearman's test. As a result, there was a trend towards an increase in body mass index in patients with chronic obstructive pulmonary disease in different countries and an improvement in spirographic parameters in a cohort of patients with chronic obstructive pulmonary disease over time. The data of the reviewed studies indicate the presence of a relationship between chronic obstructive pulmonary disease and nutritional status. At the same time, the mechanisms of the relationship between the pathogenesis of chronic obstructive pulmonary disease and adipose tissue dysfunction, as well as the role of adipose tissue and body composition in the course of the disease and its prognosis, have not been sufficiently studied.
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About the authors
Daria A. Prokonich
Siberian State Medical University
Author for correspondence.
Email: polyanskaya_darya7@mail.ru
ORCID iD: 0000-0003-4750-4364
SPIN-code: 9577-9944
M.D., PhD Stud., Assistant, Depart. of Faculty Therapy with a Course of Clinical Pharmacology; Department of Endocrinology, Clinics of Siberian State Medical University
Russian Federation, Tomsk, RussiaTatyana V. Saprina
Siberian State Medical University
Email: tanja.v.saprina@mail.ru
ORCID iD: 0000-0001-9011-8720
M.D., D. Sci. (Med.), Prof., Depart. of Faculty Therapy with a Course of Clinical Pharmacology; Head, Endocrinology Depart., Clinics of the Siberian State Medical University
Russian Federation, Tomsk, RussiaEkaterina B. Bukreeva
Siberian State Medical University
Email: kbukreeva@mail.ru
ORCID iD: 0000-0002-7699-5492
M.D., D. Sci. (Med.), Prof., Depart. of Propaedeutics of Internal Diseases with a Course of Therapy of the Pediatric Faculty
Russian Federation, Tomsk, RussiaAnna Y. Sadovnikova
Siberian State Medical University
Email: annasdvnkv@list.ru
ORCID iD: 0000-0002-4802-1340
student
Russian Federation, Tomsk, RussiaAnastacia K. Chuprunova
Siberian State Medical University
Email: cupikp081199@mail.ru
ORCID iD: 0000-0002-1043-0675
student
Russian Federation, Tomsk, RussiaReferences
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