The association of stress level with the central serous chorioretinopathy development

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Abstract

Background. The impact of stress on the central serous chorioretinopathy development has been studied in a small number of studies, and the results are conflicting.

Aim. To assess the association of the level of individual stress with the central serous chorioretinopathy development.

Material and methods. A cross-sectional study based on a survey of 110 patients with central serous chorioretino­pathy (the main group) and 110 individuals without central serous chorioretinopathy was conducted. The stress level was assessed on the Perceived Stress Scale. Quantitative and categorical data between the groups were compared. Comparison of groups by quantitative indicator was performed using the Mann–Whitney U-test, and by categorical indicator — using the odds ratio and its 95% confidence intervals.

Results. The groups of respondents were comparable according to the main demographic indicators. The median total score for the “Overstrain” subscale in the central serous chorioretinopathy group was 12 points (Q25%–Q75% 9.25–14 points), in the control group — 10 points (Q25%–Q75% 7–12 points; p=0.0002). The median total score for the “Stress Response” subscale in the central serous chorioretinopathy group was 7 points (Q25%–Q75% 5–8 points), in the control group it was 4 points (Q25%–Q75% 3–7 points; p=0.000003). In the group with central serous chorioretinopathy, compared with the control group, the proportion of people with moderate stress level was higher (74.5% vs. 53.6%; odds ratio 2.53, 95% confidence interval 1.43÷4.48) and the proportion of people with low stress level was lower (19.1% vs. 45.5%; odds ratio 0.28, 95% confidence interval 0.15÷0.52).

Conclusion. The study demonstrated the association of stress with the development of central serous chorioretinopathy.

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About the authors

Gulshat R. Khasanova

Kazan State Medical University

Email: gulshatra@mail.ru
ORCID iD: 0000-0002-1733-2576
SPIN-code: 6704-2840
Scopus Author ID: 6507469219

M.D., D.Sci. (Med.), Prof., Head, Depart. of Epidemiology and Evidence-Based Medicine

Russian Federation, Kazan, Russia

Damir R. Agliullin

Kazan State Medical University

Author for correspondence.
Email: dr.agliullin@gmail.com
ORCID iD: 0000-0001-7474-609X
SPIN-code: 1356-0270
Scopus Author ID: 57216211079

M.D., Assistant, Depart. of Epidemiology and Evidence-Based Medicine

Russian Federation, Kazan, Russia

Elmira A. Abdulaeva

Kazan State Medical Academy — branch of the Russian Medical Academy of Continuing Postgraduate ­Education

Email: abd@inbox.ru
ORCID iD: 0000-0003-3538-9354
SPIN-code: 9611-1344
Scopus Author ID: 57204855428

M.D., Cand. Sci. (Med.), Assoc. Prof., Head, Depart. of Ophthalmology

Russian Federation, Kazan, Russia

Nikita D. Kuzmin

Kazan State Medical University

Email: skouzmin21@list.ru
ORCID iD: 0000-0003-4394-3378

Student

Russian Federation, Kazan, Russia

Arthur U. Karimov

Kazan State Medical Academy — branch of the Russian Medical Academy of Continuing Postgraduate ­Education; Republican Clinical Hospital

Email: ydalis@yandex.ru
ORCID iD: 0000-0002-9870-3497
SPIN-code: 3119-1893

M.D., Cand. Sci. (Med.), psychotherapist, Tatarstan Republican Clinical Hospital; Assistant, Depart. of Clinical Pharmacology and Pharmacotherapy

Russian Federation, Kazan, Russia; Kazan, Russia

Saida T. Agliullina

Kazan State Medical University

Email: saida.agliullina@kazangmu.ru
ORCID iD: 0000-0003-4733-6911
SPIN-code: 2079-1833
Scopus Author ID: 57200421742
Russian Federation, Kazan, Russia

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