The state of hemostasis in salmonella intoxication

In recent years, there have been reports of the development of thrombohemorrhagic syndrome in patients with salmonellosis. We also observed 7 patients with salmonellosis who had clinically pronounced thrombohemorrhagic syndrome. The course of the disease in one of them was complicated by massive bleeding into the parenchyma of the lungs, in the other by hemorrhage into the brain substance. In 2 patients, thrombosis of mesenteric vessels was detected, in 3 — multiple hemorrhages in the mucous membranes of the small intestine and in 3 — colon. Thrombohemorrhagic syndrome developed against the background of toxic and infectious shock, which led to fatal outcomes. It is known that with salmonella intoxication in the patient's body, not only hemodynamic disorders develop, but also symptoms of the direct effect of endotoxin on the tissues of various organs and systems are revealed.