Experience of simultaneous use of single-photon emission and X-ray computed tomography in cancer patients with fibrous dysplasia

Cover Page


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Aim — to present the results of using single-photon emission computed tomography combined with X-ray computed tomography in the process of diagnosing osteodestructive changes in cancer patients with a rare comorbidity — fibrous dysplasia. In the consultative and diagnostic department of the Federal State Budgetary Institution “National Medical Research Center of Oncology” of the Ministry of Health of Russia, Rostov-on-Don, in 2021, 2 patients with fibrous dysplasia of the skull bones and synchronous oncological diseases were examined. The patients underwent a complex of diagnostic tests: spiral X-ray computed tomography of the head, chest, abdominal cavity and small pelvis, bone scintigraphy, single-photon emission computed tomography combined with X-ray computed tomography of the skeleton bones, and puncture biopsy under ultrasound control. The described clinical observations clearly demonstrate examples of a phased diagnostic oncological search in patients without pathognomonic clinical manifestations and with multiple lesions of the skull bones. An increase in diagnostic information content in the differential diagnosis of fibrous dysplasia of the skeleton bones and bone metastases is facilitated by single-photon emission computed tomography combined with X-ray computed tomography. The combination of these two hybrid technologies provides an opportunity to simultaneous determination of the volume and localization of lesions, timely conduction of differential diagnostics and, in turn, maximum optimization of the examination and management of patients in this category.

Full Text

Restricted Access

About the authors

Natalia A. Maksimova

National Medical Research Center of Oncology

Email: maximovanataly@mail.ru
ORCID iD: 0000-0002-0400-0302
SPIN-code: 1785-9046

M.D., D. Sci. (Med.), Prof., Head, Radioisotope Laboratory with Ultrasonic Diagnostics Group

Russian Federation, Rostov-on-Don, Russia

Marina A. Arzamastseva

National Medical Research Center of Oncology

Email: marinaarz64@yandex.ru
ORCID iD: 0000-0002-1926-3463
SPIN-code: 7643-2081

M.D., Cand. Sci. (Med.), radiologist, Radioisotope Laboratory with Ultrasonic Diagnostics Group

Russian Federation, Rostov-on-Don, Russia

Elena I. Agarkova

National Medical Research Center of Oncology

Author for correspondence.
Email: agarkovaei82@mail.ru
ORCID iD: 0000-0001-9243-1665
SPIN-code: 3467-4388

M.D., Cand. Sci. (Med.), radiologist, Radioisotope Laboratory with Ultrasonic Diagnostics Group

Russian Federation, Rostov-on-Don, Russia

Mariya G. Ilchenko

National Medical Research Center of Oncology

Email: maria_ilchenko80@mail.ru
ORCID iD: 0000-0002-9126-0646
SPIN-code: 2856-7946

M.D., Cand. Sci. (Med.), radiologist, Radioisotope Laboratory with Ultrasonic Diagnostics Group

Russian Federation, Rostov-on-Don, Russia

Marina A. Engibaryan

National Medical Research Center of Oncology

Email: mar457@yandex.ru
ORCID iD: 0000-0001-7293-2358
SPIN-code: 1764-0276

M.D., D. Sci. (Med.), Head, Depart. of Head and Neck Tumors

Russian Federation, Rostov-on-Don, Russia

Olga V. Pandova

National Medical Research Center of Oncology; Rostov State Medical University

Email: agarkovaei82@mail.ru
ORCID iD: 0000-0003-2218-9345

M.D., Cand. Sci. (Med.), neurologist, Depart. of Neurooncology, National Medical Research Centre for Oncology; Assistant, Depart. of Oncology

Russian Federation, Rostov-on-Don, Russia; Rostov-on-Don, Russia

References

  1. Fritzsche H, Schaser K-D, Hofbauer C. Benigne Tumoren und tumorähnliche Läsionen des Knochens. Der Orthopäde. 2017;46:484–497. doi: 10.1007/s00132-017-3429-z.
  2. Dobrotin VE. Albright's syndrome as a form of fibrous dysplasia. Russkiy meditsinskiy zhurnal. 2015;(23):1422–1424. (In Russ.)
  3. Voronovich IR, Pashkevich LA. Fibrous dysplasia of ribs. Meditsinskie novosti. 2014;(7):61–64. (In Russ.)
  4. Chen YR, Wong FH, Hsueh C, Lo LJ. Compu¬ted tomography characteristics of non-syndromic craniofacial fibrous dysplasia. Chang Gung Med J. 2002;25(1):1–8. PMID: 11926581.
  5. Kugushev AYu, Lopatin AV. Modern approaches to diagnostics and treatment of craniofacial fibrous dysplasia. Detskaya khirurgiya. 2017;21(2):93–98. (In Russ.) doi: 10.18821/1560-9510-2017-21-2-93-98.
  6. Singh G, Rock P. Fibrous dysplasia. Reference ¬article, Radiopaedia.org. Last revised by Patrick J Rock on 22 May 2021. https://radiopaedia.org/articles/fibrous-dysplasia (access date: 01.10.2021).
  7. Sviridov EG, Kadykova AI, Redko N, Drobyshev AYu, Deev RV. Genetic heterogenety of tumour-like lesions of bones in maxillofacial area. Genes & cells. 2019;14(1):49–54. (In Russ.) doi: 10.23868/201903006.
  8. Gupta D, Garg P, Mittal A. Computed tomography in craniofacial fibrous dysplasia: A case series with review of literature and classification update. Open Dent J. 2017;11:384–403. doi: 10.2174/1874210601711010384.
  9. Lee J, FitzGibbon E, Chen Y, Kim HJ, Lustig LR, Akintoye SO, Collins MT, Kaban LB. Clinical guidelines for the management of craniofacial fibrous dysplasia. Orphanet J Rare Dis. 2012;S2:7. doi: 10.1186/1750-1172-7-S1-S2.
  10. Otolaringologiya. Natsional’noe rukovodstvo. (Otolaringology. National guidelines.) V.T. Palchun, editor. Moscow: GEOTAR-Media; 2008. 960 p. (In Russ.)
  11. Zhang L, He Q, Li W, Zhang R. The value of 99mTc-methylene diphosphonate single photon emission computed tomography/computed tomography in diagnosis of fibrous dysplasia. BMC Med Imaging. 2017;17(1):46. doi: 10.1186/s12880-017-0218-4.
  12. Hatano H, Morita T, Ariizumi T, Kawashima H, Ogose A. Malignant transformation of fibrous dysplasia: A case report. Oncol Lett. 2014;8(1):384–386. doi: 10.3892/ol.2014.2082.
  13. Terekhova TN, Kushner AN, Karmalkova EA. Khi¬rurgicheskaya stomatologiya detskogo vozrasta. Uchebno-metodicheskoe posobie. (Pediatric surgical dentistry. Study guide.) Minsk: BGMU; 2009. 100 р. (In Russ.)
  14. Maksimova NA, Arzamastseva MA, Agarkova EI, Engibaryan MA. Capabilities of single-photon emission computed tomography combined with compu¬ted tomography in diagnosis of neck masses. Kazan Medi¬cal Journal. 2018;99(2):330–336. (In Russ.) doi: 10.17816/KMJ2018-330.
  15. Timofeeva LA, Aleshina TN. The significance of SPECT-CT for differential diagnosis of palpable abnormalities in thyroid body. Mezhdunarodnyy meditsinskiy zhurnal. 2016;4(10):34–37. (In Russ.)
  16. Al-Bulushi NK, Abouzied ME. Comparison of 18F-FDG PET scan and Tc-99m-MDP bone scintigraphy in detecting bone metastasis in head and neck tumors. Nucl Med Commun. 2016;37(6):583–588. doi: 10.1097/MNM.0000000000000479.
  17. Kit OI, Duritskiy MN, Shelyakina TV, Maksimova NA, Legostaev VM. Modern ways of optimization of organizational forms of malignant neoplasm prevention. Modern problems of science and education. 2015;(4):293. (In Russ.)
  18. Diaconis P, Holmes S, Montgomery R. Dynamical bias in the coin toss. SIAM Rev. 2007;49(2):211–235. doi: 10.1137/S0036144504446436.

Supplementary files

Supplementary Files
Action
1. Рис. 1. Пациент Р. Однофотонная эмиссионная компьютерная томография, совмещённая с рентгеновской компьютерной томографией, костей черепа

Download (18KB)
2. Рис. 2. Пациент Р. Трёхмерная компьютерная томография костей черепа

Download (23KB)
3. Рис. 3. Пациентка М. Однофотонная эмиссионная компьютерная томография, совмещённая с рентгеновской компьютерной томографией, костей черепа

Download (16KB)
4. Рис. 4. Пациентка М. Трёхмерная компьютерная томография костей черепа

Download (27KB)

© 2022 Eco-Vector





This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies