Analysis of own observations of visceral syphilis lethal outcomes
- Authors: Nadeev A.P.1, Krivosheev A.B.1, Pakhomova A.E.1, Travin M.A.1, Pakhomova E.E.1
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Affiliations:
- Novosibirsk State Medical University
- Issue: Vol 103, No 2 (2022)
- Pages: 302-308
- Section: Clinical experiences
- URL: https://kazanmedjournal.ru/kazanmedj/article/view/99545
- DOI: https://doi.org/10.17816/KMJ2022-302
- ID: 99545
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Abstract
The epidemiological situation of the syphilis incidence in the modern world is characterized as a “hidden” epidemic, which manifests itself in latent and late forms of the disease. Despite the general trend towards a decrease in the incidence of syphilis, there are some specific features in many regions of Russia. Deaths from visceral syphilis are now rare. The article presents data on the epidemiology, nosological forms of visceral syphilis, and describes two lethal outcomes. In observations, late syphilis was characterized by damage to several organs (liver, lungs, heart, brain), but the leading clinical manifestations were neurosyphilis (syphilitic meningoencephalitis) and cardiovascular syphilis (syphilitic mesaortitis, interstitial myocarditis). Damage of the respiratory and digestive organs (stomach, liver) are rare forms of visceral syphilis. In the presented observations, gummas in the lungs and liver, which were not clinically diagnosed, were detected. In all cases, the diagnosis of visceral syphilis was established at autopsy on the basis of a characteristic morphological picture (detection of gummas) and positive results of the Wassermann reaction.
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About the authors
Aleksander P. Nadeev
Novosibirsk State Medical University
Author for correspondence.
Email: nadeevngma@mail.ru
ORCID iD: 0000-0001-9428-2835
M.D., D. Sci. (Med.), Prof., Head, Depart. of Pathological Anatomy
Russian Federation, Novosibirsk, RussiaAlexander B. Krivosheev
Novosibirsk State Medical University
Email: krivosheev-ab@narod.ru
ORCID iD: 0000-0002-4845-8753
M.D., D. Sci. (Med.), Prof., Depart. of Faculty Therapy
Russian Federation, Novosibirsk, RussiaAngelina E. Pakhomova
Novosibirsk State Medical University
Email: pakhomova@ockk.ru
ORCID iD: 0000-0001-7541-6391
Student, Internat. School “Medicine of the Future”
Russian Federation, Novosibirsk, RussiaMikhail A. Travin
Novosibirsk State Medical University
Email: mtravin@mail.ru
ORCID iD: 0000-0001-6385-5784
M.D., Cand. Sci. (Med.), Assoc. Prof., Depart. of Pathological Anatomy
Russian Federation, Novosibirsk, RussiaEkaterina E. Pakhomova
Novosibirsk State Medical University
Email: pakhomova@ockk.ru
ORCID iD: 0000-0001-9256-3094
Student, Institute of Clinical Medicine
Russian Federation, Novosibirsk, RussiaReferences
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