Changes in some immunity parameters in dental caries

In the process of studying the effectiveness of anti-carious vaccination, developed as a result of establishing the microbial etiology of dental caries, a lot of data have been obtained about the regular dependence of dental caries on the content of secretory IgA in saliva. However, the information about the relationship between dental caries and the content of serum immunoglobulins of the major classes in blood and saliva is very contradictory. Some authors give data that allow to think about the dependence of dental caries on the concentration of serum IgA and, to a lesser extent, IgG I, while other authors reject the possibility of such a connection. The state of cellular immunity in caries remains practically unstudied.