Ultrasonic indicators of the heart and carotid arteries in arterial hypertension development in patients with chronic obstructive pulmonary disease

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Aim. To specify the sequence of changes in the functional parameters of arterial hypertension in patients with chronic obstructive pulmonary disease and asthma according to the results of echocardiography, carotid arteries duplex scan and ambulatory blood pressure monitoring.

Methods. Ambulatory blood pressure monitoring, tissue Doppler echocardiography and carotid artery duplex scan were performed in 160 patients with chronic obstructive pulmonary disease, arterial hypertension, asthma, and 33 apparently healthy volunteers of both sexes aged 39-70 years.

Results. In patients with chronic obstructive pulmonary disease, an increase in hypertensive indices of time and area with the development of non-dipper or inverse-dipper 24-hour blood pressure profile disturbances is registered only at night hours. In chronic obstructive pulmonary disease, unlike asthma, carotid arteries thickening, combined hypertrophy and diastolic dysfunction of both ventricles develop. The prevalence of the thickening of «intima-media» complex and atherosclerotic plaques among patients with comorbid pathology (chronic obstructive pulmonary disease + arterial hypertension) occurs significantly more frequently than in the groups with hypertension or chronic obstructive pulmonary disease, confirming the synergistic effect of the considered nosologies on the atherosclerotic process.

Conclusion. In patients with chronic obstructive pulmonary disease changes of the ultrasonic and functional indicators of the cardiovascular system, typical for arterial hypertension are registered starting with stage I and amplified with increase in the disease severity, leading to the need of diagnostic and therapeutic management correction.

About the authors

E G Akramova

Central Municipal Clinical Hospital №18; Kazan State Medical Academy; Kazan State Medical University

Author for correspondence.
Email: akendge@rambler.ru


  1. Мухарлямов Н.М. Лёгочное сердце. М.: Медицина. 1973; 263 с.
  2. Almagro P., Cabrera F.J., Diez J. et al. Comorbidities and short-term prognosis in patients hospitalized for acute exacerbation of COPD. The ESMI study. Chest. 2012; 142 (5): 1126-1133. http://dx.doi.org/10.1378/chest.11-2413
  3. Haeusler K.G., Herm J., Konieczny M. et al. Impact of chronic inflammatory airway disease on stroke severity and long-term survival after ischemic stroke - a retrospective analysis. BMC Neurol. 2015; 15: 164. http://dx.doi.org/10.1186/s12883-015-0414-1
  4. Hermida R.C., Smolensky M.H., Ayala D.E., Portaluppi F. 2013 ambulatory blood pressure monitoring recommendations for the diagnosis of adult hypertension, assessment of cardiovascular and other hypertension-associated risk, and attainment of therapeutic goals. International Society for Chronobiology; American Association of Medical Chronobiology and Chronotherapeutics; Spanish Society of Applied Chronobiology, Chronotherapy, and Vascular Risk; Spanish Society of Atherosclerosis; Romanian Society of Internal Medicine. Chronobiol. Int. 2013; 30 (3): 355-410. http://dx.doi.org/10.3109/07420528.2013.750490
  5. Lahousse L., Tiemeier H., Ikram M.A., Brusselle G.G. Chronic obstructive pulmonary disease and cerebrovascular disease: A comprehensive review. Respir. Med. 2015; 109 (11): 1371-1380. http://dx.doi.org/10.1016/j.rmed.2015.07.014
  6. Park H.J., Leem A.Y., Lee S.H. et al. Comorbidities in obstructive lung disease in Korea: data from the fourth and fifth Korean National Health and Nutrition Examination Survey. Int. J. Chron. Obstruct. Pulmon. Dis. 2015; 10: 1571-1582. http://dx.doi.org/10.2147/COPD.S85767
  7. Portegies M.L., Lahousse L., Joos G.F. et al. Chronic obstructive pulmonary disease and the risk of stroke: the Rotterdam study. Am. J. Respir. Crit. Care Med. 2015 Sep. 28. http://www.ncbi.nlm.nih.gov/pubmed/26414484 (access date: 10.11.2015). http://dx.doi.org/10.1164/rccm.201505-0962OC

© 2016 Akramova E.G.

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