Experience of the use of bronchophonography in the diagnosis of hyperventilation syndrome


Aim. To study the capability of applying the method of acoustic analysis of respiration (bronchophonography) in the diagnosis of hyperventilation syndrome and mild bronchial asthma and in differential diagnosis between them.

Methods. 97 subjects were examined (35 men and 62 women, average age 36.4±13.4 years), divided into the groups: control (healthy subjects) - 38 subjects (18 men and 20 women, average age 33.6±14.0 years), patients with mild bronchial asthma - 37 subjects (12 men and 25 women, average age 40.7±13.7 years), patients with hyperventilation syndrome - 22 subjects (5 men and 17 women, average age 35.0±12.6 years). All patients, except for general clinical examination, underwent spirometry, bronchophonography and Nijmegen questionnaire.

Results. Acoustic breathing patterns of all groups were formed, spirometric and bronchophonographic indicators were analyzed. Bronchophonography revealed significant intergroup differences in different frequency ranges in groups of patients with bronchial asthma and hyperventilation syndrome as well as the absence of those between healthy individuals and patients with hyperventilation syndrome. At the same time, the data of spirometry did not allow differentiation of mild bronchial asthma and hyperventilation syndrome and in most cases did not differ from those of healthy individuals.

Conclusion. Spirometry cannot serve as a reliable diagnostic criterion in the diagnosis and differential diagnosis of hyperventilation syndrome and mild bronchial asthma; differences in acoustic indices of respiration in bronchophonography allow such differentiation.

K A Magomedova

Dagestan State Medical University

Email: ajub@inbox.ru
Makhachkala, Russia

A A Guseynov

Dagestan State Medical University

Author for correspondence.
Email: ajub@inbox.ru
Makhachkala, Russia

N U Chamsutdinov

Dagestan State Medical University

Email: ajub@inbox.ru
Makhachkala, Russia

  1. Respiratornaya meditsina. Rukovod­stvo. (Respiratory medicine. A guide. In 3 volums.) Ed. by A.G. Chuchalin. 2nd ed., suppl. Moscow: Litterra. 2017; 2: 544 p. (In Russ.)
  2. Maskell N., Millar A. Oxford desk reference: Respiratory medicine. Oxford. 2009; 496 p. Russ. ed.: Rukovodstvo po respiratornoy me­ditsine. Moscow: GEOTAR-Media. 2014; 600 p. (In Russ.)
  3. Topolyanskiy V.D., Strukovskaya M.V. Psikhosomaticheskie rasstroystva. Rukovodstvo dlya vrachey. (Psychosoma­tic disorders. A guide for doctors.) 2nd ed. Moscow: ­GEOTAR-Media. 2015; 544 р. (In Russ.)
  4. Daragan N.V., Chikina S.Y. Hyperventilation syndrome in practical work of a pneumologist: pathogenesis, clinical features, diagnosis. Pul'monologiya. 2011; (5): ­87–96. (In Russ.)
  5. Abrosimov V.N., Byalovskiy Yu.Yu., Subbotin S.V., Ponomareva I.B. Volumetric capnography: abi­lities in practical pulmonology. Pul'monologiya. 2017; 27 (1): ­65–70. (In Russ.)
  6. Magomedova K.A., Guseynov A.A. Possible applications bronchophonography in the differential diagnosis of respiratory disorders in bronchial asthma and somatoform dysfunction of the autonomic nervous system. Vestnik Dagestanskoy gosudarstvennoy meditsinskoy akademii. 2016; (3): 17–20. (In Russ.)
  7. Filatova E.G. Neurogenic respiratory disorders: hyperventilation syndrome. Lechashchiy vrach. 2007; (9): 70–72. (In Russ.)
  8. Thomas M., McKinley R.K., Freeman E., Foy C. Prevalence of dysfunctional breathing in patients treated for asthma in primary care: cross sectional survey. Brit. Med. J. 2001; 322: 1098–1100. doi: 10.1136/bmj.322.7294.1098.
  9. Le A.V., Simon R.A. The difficult-to-control asthmatic: a systematic approach. Allergy, Asthma, and Clin. Immunol. 2006; 2 (3): 109–116. doi: 10.1186/1710-1492-2-3-109.
  10. Van Dixhoorn J., Folgering H. The Nijmegen Questionnaire and dysfunctional breathing. ERJ Open Res. 2015; 1: 00001-2015. doi: 10.1183/23120541.00001-2015.
  11. Snaith R.Ph. The hospital anxiety and depression scale. Health and Quality of Life Outcomes. 2003; 1: 29. doi: 10.1186/1477-7525-1-29.
  12. Komp'yuternaya bron­khofonografiya respiratornogo tsikla. (Computed broncho­phonography of the respiratory cycle.) Ed. by N.A. Geppe, V.S. Malyshev. Moscow: Media Sfera. 2016; 108 p. (In Russ)
  13. Gusey­nov A.A., Aysanov Z.R., Chuchalin A.G. Acoustic analysis of respiratory sounds: state of the issue. Pul'monologiya. 2005; (6): 105–112. (In Russ.)


Abstract - 22

PDF (Russian) - 45


© 2019 Magomedova K.A., Guseynov A.A., Chamsutdinov N.U.

Creative Commons License

This work is licensed
under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Свидетельство о регистрации СМИ ЭЛ № ФС 77-75008 от 1 февраля 2019 года выдано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор)