Anti-carious effect of xylitol when used locally

Abstract

The effect of irrigation of the oral cavity with 10% xylitol solution on the development of dental caries was evaluated in an experiment on animals receiving cariesogenic diet. The study was conducted on 123 30-day-old white mongrel rats for 120 days. The 1st group of animals kept on a cariesogenic diet according to IA Begelman et al. [2] served as a control. Group 2 received the same cariesogenic diet, but 10% sucrose was replaced with xylitol. Group 3 animals, who were also on a cariesogenic diet, had their mouths irrigated with a 10% solution of xylitol.