Vol 74, No 1 (1993)
Clinical aspects of the use of recombinant interferon preparations
Abstract
One of the modern trends in the prevention and treatment of viral, immunodeficient and oncological diseases is the use of drugs of the interferon group (IF). This is facilitated by the creation of a number of new highly effective recombinant IFs exhibiting not only antiviral, but also pronounced antiproliferative and immunomodulatory properties.
Low-intensity (helium-neon) laser therapy in an emergency cardiology clinic
Abstract
Cardiologists pay great attention to the treatment of coronary heart disease (IHD), as well as prevention, improving the already known and developing new methods. Of the latter, laser therapy is of particular interest, in particular, the use of low-intensity laser radiation is promising, which is quickly gaining a place among the known non-drug methods of treatment in therapeutic practice.
Dimephosphone — vasoactive drug for normalization of nervous system function
Abstract
An experimental study of dimephpsphone, using different models of the disorders of cerebrum and cerebral circulation functions, reveals cerebroprotcctive properties and normalizing type of the effect on the regulating mechanisms of cerebral circulation. Clinical tests indicate the efficacy of the drug in different central nervous system diseases in neurological and neurosurgical clinics.
Chronic overdose of oral antidiabetic drugs
Abstract
The introduction of new drugs into medical practice is accompanied by the need to solve such a problem as the correct choice of the drug, the identification of its toxic manifestations and side effects. Of practical importance is the syndrome of chronic insulin overdose (CSI) - Samoji syndrome, which is characterized by paradoxical hyperglycemia in response to an increase in the dose of insulin.
Functional state and stress periods of cardiovascular and sympathetic-adrenal systems in students throughout the academic year
Abstract
The dynamics of a functional state of cardiovascular and sympathetic — adrenal systems in students aged 17—19 years throughout the academic year in the first, second and third УДК 616.921.5-06-037 course of the Pedagogical Institute is studied. The adaptation process of students is shown to be accompanied by stress periods in the functional state of cardiovascular and sympathetic — adrenal systems. The response of the systems under study to the dosed physical load varies according to their functioning intensity. The character of correlative relations between hormonal and mediative links of sympathetic — adrenal system and statistical characteristics of the cardiac rhythm depends ’on the training period and may serve as a criterion of the functional stress of the student’s organism.
Prediction of bacterial complications of influenza
Abstract
Forty — six clinicoanamnestic and laboratory signs are tested for suitability to predict bacterial complications of influenza by means of Vald’s succesive statistical analysis. The majority of the most informative signs represent the characteristics, reflecting the opsonocutophagic system state. On the basis of the data obtained the diagnostic table to predict the bacterial complications of influenza on days 1—5 of the disease is prepared, allowing to determine objectively the indications for antibacterial therapy in influenza.
Endotox1nemy and bronchial obstruction syndrome in respiratory viral infections in children
Abstract
As many as 101 patients with acute respiratory viral infections (ARVI) aged 3 months to 3 years are examined, of these in 51 patients the disease going with bronchoobstructive syndrome. According to the level of antiendotoxinal antibodies, plasma endotoxin and that connected by polymorphonuclear leukocytes, it is established that the acute period of acute respiratory viral infections with bronchoobstructive syndrome goes in the presence of pronounced cellularly connected endotoxinemy. The exact dependence is revealed between plasma endotoxin content and pronounced physical variations in respiratory organs in this form of the disease. Viral and bacterial nature of respiratory infections in children is confirmed by the assessment of the level of antiviral and antiendotoxinal antobodies. The data obtained allow suggesting the possible participation of endotoxin in genesis of bronchial obstruction in acute respiratory viral infections.
The effectiveness of treatment of patients with pulmonary tuberculosis with multiple decay cavities
Abstract
Pulmonary tuberculosis with multiple decay cavities is classified as a common destructive process and is treated with more intensive methods. We have drawn attention to the fact that the processes with the number of cavities more than one are very different in the nature of the flow. Having accumulated a sufficient number of observations over 15 years, we decided to conduct a separate analysis of the clinical course of the disease and evaluate the effectiveness of some methods of complex therapy in different types of pulmonary tuberculosis with multiple decay cavities.
Clinicoroentgenologic peculiarities of eosinophilic infiltrates of lungs with prolonged and relapsing course
Abstract
Clinical and roentgenologic data of 74 patients with different forms of eosinophilic infiltrates, of lungs are analyzed. A number of peculiaritis of the clinicoroentgenologic picture with prolonged course, more pronounced clinical manifestations, higher levels of leukocytosis, and blood eosinophilia, a possibility of cavities creation, a decrease of the volume of affected lungs sites are revealed. The difficulties of differential diagnosis are stressed.
Comparison assessment of diagnosis and treatment methods of intussusception in children
Abstract
The results of the treatment of 107 children aged 3 months to 3 years with intussusception are. analyzed. Diagnostic and medical pneumoirrigoscopy is used principally in children to 1 year with remoteness of the disease up to 12—24 h with efficacy in 41,3%. Conservative disinvagination under anesthesia is applied in remoteness of the disease up to 48 h and is successful in 92,1 % of the children. This method has failed in intestine necrosis. Higher efficacy of the treatment under anesthesia is due evidently to the decrease of colic in invagination region and the lack of ray loading, promoting greater persistence of a doctor. It is worthwhile to determine the treatment method (conservative or operational) not by remoteness of the disease but by a patient’s state.
Chande of fibronectin concentration in erysipelas
Abstract
The role of plasma fibronectin in hemostasis system in erysipelas, depending on the disease gravity and pronounced hemorrhagic syndrome, is studied. The results obtained indicate that different phases of disseminated intravascular blood coagulability syndrome are determined, depending directly on the disease gravity in patients with erysipelas at the height of the disease in the presence of the decrease of plasma fibronectine. The decrease of plasma fibronectine in heavy infectious disease is connected with its consumption in the process of intravascular microthrombogenesis and presents a unique protective response of the macroorganism to the action of pathogene toxins.
Fibronectin of blood plasma in heavy forms of eczema, atopic dermatitis and psoriasis
Abstract
Fibronectin (Fn) level of blood plasma is studied by the immunofermental method in patients with heavy forms of eczema, psoriasis and atopic dermatitis. An increase of Fn level of blood plasma is revealed in all groups under examination, having no tendency for a decrease in clinical improvement. The results of investigation of the nature and dynamics of Fn characteristics in specific patients allow considering them as the factors, reflecting the integral characteristics of reactivity of the changed connective tissue of derma. The definite types of correlations peculiar to each of dermatoses are determined, relating Fn levels with other characteristics, typical of inflammatory process.
Medicosocial rehabilitation or patients with urinary bladder cancer after cystectomy
Abstract
The results of the treatment of 251 patients after cystectomy with different methods of urine removal are analyzed, of these 171 patients after the operation of urinary bladder substitution by the isolated segment of intestine with the recovery of uresis by urethra. The recovery of uresis by urethra after cystectomy provides favourable physical, psychological and social conditions for patients, the possibility to resume their professional active life. A two-stage operation of the formation of urinary reservoir from the segment of intestine with the recovery of transurethral uresis is described. The main criteria of rehabilitation of patients with urinary bladder cancer after cystectomy must be taken as the recovery of natural uresis by urethra as well as the normalization of functional state of kidneys, upper and lower urinary tracts.
Variations of testicles of subfertile men with epidemic patiditis in anamnesis
Abstract
The investigation data of testicles bioptates of 153 subfertile men are given. The examined patients are divided into 2 groups: the first group includes subfertile men with epidemic parotidits in anamnesis (91), the second one includes subfertile men, never being ill with epidemic parotiditis (62). The peculiarity lies in the fact that the morphologic variations of testicles of subfertile men with epidemic parotiditis in anamnesis are similar to the variations of autoimmune nature.
Combination of antiglaucomatous surgery and cataract extraction by corneal incision
Abstract
The combination of primary. Glaucoma and cataract in one eye, according to different authors, occurs from 3 to 17%. Some authors recommend in such cases step-by-step operations - at the beginning antiglaucomatous, and then, at various times after it, cataract extraction. Other ophthalmic surgeons, especially in recent decades, prefer the option of combining antiglaucomatous surgery with cataract extraction by an incision along the limbus.
The choice of the time of intraosseous implantation in the lateral part of the jaws
Abstract
implantation of artificial supports for fixing prostheses has become increasingly widespread. Most often, intraosseous implantation is used in bone tissue that is completely rebuilt after tooth extraction [1]. By the time of complete restructuring of the alveolar process of the jaw at the site of removal, it significantly decreases in volume and intraosseous implantation can be difficult. At the same time, implantation directly into the socket of the extracted tooth contributes to the implementation of the principle of early prosthetics, which prevents atrophic tissue changes. An essential advantage of direct implantation is the possibility of a single surgical intervention combining tooth extraction and implantation. Despite this, implantation into the socket of the extracted tooth is rarely performed, and, as a rule, in the area of single-rooted teeth of the upper jaw [3]. In the literature, there is almost no information about the features and effectiveness of direct implantation in the area of the chewing teeth. Carrying out such an analysis is very important, and it was the purpose of this study.
Edotoxin of gram-negative bacteria and gestosis
Abstract
Gestosis continues to occupy one of the leading places among the problems of modern obstetrics. The frequency of this pathology varies, according to the literature, from 1.5 to 17.6%. They represent a complex neurohumoral pathological process with changes in liver function. kidneys, cardiovascular system, hemostasis system, immunogenesis, metabolic processes, which increases the risk of septic complications, including gram-negative etiology.
Primary vasculitis with predominant tongue involvement
Abstract
В литературе имеются лишь единичные сообщения о первичном васкулите с поражением сосудов одного органа (легких, сердца, почек либо печени). В этой связи может быть представлен приводимый случай васкулита с некрозом половины языка, так как подобных сообщений в литературе мы не нашли.
A case of Niemann-Pieck storage disease in a 4 month old baby
Abstract
Niemann-Pick storage disease is rare. The disease is based on excessive accumulation of sphingomyelin as a result of a defect in the enzyme sphingomyelinase, which is transmitted in an autosomal recessive manner. In the affected organs, an increase in the content of total lipids is found, especially sphingomyelin, as well as other phospholipids and cholesterol.
Difficulties in ECG diagnosis of myocardial infarction
Abstract
Until now, in the diagnosis of myocardial infarction (MI), the main importance is attached to ECG studies. In the MI focus, an ischemic zone is formed, which is characterized by a change in the repolarization process (T wave), an injury zone manifested by a displacement of the ST segment and a necrosis zone, which is expressed in a change in the QRS complex.
Changes in the function of external respiration in children in ecologically unfavorable areas of an industrial city
Abstract
In connection with urbanization, the study of the influence of atmospheric pollution on the health of the population is an urgent task. The study of the respiratory system is of particular importance, since the respiratory organs are exposed to the harmful effects of pollutants in the first place. However, the influence of harmful substances on the bronchopulmonary system in the prenosological period has not been sufficiently studied, since the functional state of the body is more sensitive to the effects of environmental factors than the incidence rates.
Centile probabilities of hemoglobin levels in children of school age
Abstract
Hemoglobin indexed are analyzed in 2807 children in Kazan, Nizhnekamsk and in three Arsky) of Tatarstan Republik. Centile probabiagricultural regions (Apastovsky, Aktanyshsky, lities of hemoglobin concentration in children of school age are obtained by means of the nonparametrical statistical analysis. This method may be used to estimate the variations of individual indexes of hemoglobin in dynamics in preventive medicine.
The method of catheterization of the branches of the subclavian artery
Abstract
Difficulties in catheterization of the right vertebral artery significantly reduce the diagnostic capabilities of angiography. For the same reasons, selective and superselective catheterization of the branches of the subclavian artery for intra-arterial administration of drugs is also complicated.
Production technology and strength properties of porous permeable materials based on titanium and titanium nickelide for dental implantology
Abstract
Currently, for dental implantology, structures from porous permeable materials based on titanium and titanium nickelide have been proposed and substantiated. The main advantages of titanium in comparison with other medical materials based on metals and alloys (stainless steel, alloys based on cobalt, chromium, nickel) are high elasticity, sufficient mechanical strength, and increased corrosion resistance in biological media. Porous titanium also retains these qualities. However, titanium, including porous titanium, has some disadvantages: low shear resistance, low wear resistance, and increased fatigue. For porous titanium, these disadvantages are partially leveled after the growth of bone tissue in the pores of the implant and the formation of a composite "porous metal-bone tissue"; nevertheless, they limit the use of titanium.
Device for the prevention of wound infection
Abstract
In emergency abdominal surgery, in order to prevent wound infection, achieved by increasing the efficiency of postoperative wound treatment, as well as to exclude splashing of wound discharge, we have developed a device, the funnel of which has an elastic continuation in the form of a foam rubber skirt. The holes on the funnel are made in the form of nozzles at an angle to the axis of the device and directed towards the center.
The use of gelatin in the polarographic study of serum proteins
Abstract
In order to search for new objective methods that complement the diagnostic complex for bronchopulmonary diseases, we studied the filtrate of denatured blood serum (FDSC) in patients with acute pneumonia in the dynamics of treatment using a Pa-2 polarograph (Czechoslovakia) in the mode of classical (DS) polarography. The voltammetric curves were processed according to the Hohn's method, using the cobalt wave height of the background solution as the initial wave height.
History of medicine
Abstract
I was lucky to have teachers. In the fourth year of the Faculty of Medicine of Kazan University, MN Cheboksarov was the head of faculty therapy, N.A. Gerken was the head of the surgery clinic, V.S.Gruzdev was the head of obstetrics and gynecology, and A.V. They were not only the most authoritative clinicians, but also excellent lecturers. Their auditoriums were never empty, although at that time attending lectures was optional.
Advances in modern cryobiology (Kharkov, April 21-25, 1992)
Abstract
The II International Conference, organized by the UNESCO International Institute of Cold and the Institute of Cryobiology and Cryomedicine of the Academy of Sciences of Ukraine, was attended by 242 domestic and 12 foreign specialists. 230 reports were presented at plenary sessions and 4 symposia.