Chronic obstructive pulmonary disease: an urgent problem of health saving of modern medicine

Cover Page


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Chronic obstructive pulmonary disease is one of the most urgent problems of the modern medical community. Despite the introduction of constantly updated schemes of early diagnosis and treatment into practical medicine, there is still an upward trend in the number of cases, under-examined persons, and prognostically unfavorable outcomes. The review highlights the findings of epidemiological studies confirming the widespread prevalence of the disease, accompanied by rapid disability progression, high mortality, and significant economic damage. The review lists the main exogenous and endogenous risk factors for the development of chronic obstructive pulmonary disease, including occupational etiology. Attention is drawn to the possibility of disease prevention in a professional environment with the proper motivation of the patient and the application of economic efforts. The article discusses the main causes of underdiagnosis and late diagnosis of the disease. Lifestyle modification makes an undeniable contribution to the prevention of chronic obstructive pulmonary disease and improving prognosis in the developed disease. Certain psychological characteristics that reduce adherence to treatment of such patients should be considered in organizing the management of this category of persons and creating special schools. It is important to create a classification of “endotypes” of chronic obstructive pulmonary disease, as well as sufficient public awareness about this disease with the aim of the earliest possible diagnosis.

Full Text

Restricted Access

About the authors

S V Raikova

Saratov Hygiene Medical Research Center of the Federal Scientific Center for Medical and Preventive Health Risk Management Technologies; Saratov State Medical University named after V.I. Razumovsky

Author for correspondence.
Email: matiz853@yandex.ru
Russian Federation, Saratov, Russia; Saratov, Russia

N E Komleva

Saratov Hygiene Medical Research Center of the Federal Scientific Center for Medical and Preventive Health Risk Management Technologies; Saratov State Medical University named after V.I. Razumovsky

Email: matiz853@yandex.ru
Russian Federation, Saratov, Russia; Saratov, Russia

A N Mikerov

Saratov Hygiene Medical Research Center of the Federal Scientific Center for Medical and Preventive Health Risk Management Technologies; Saratov State Medical University named after V.I. Razumovsky

Email: matiz853@yandex.ru
Russian Federation, Saratov, Russia; Saratov, Russia

M V Potapova

Saratov State Medical University named after V.I. Razumovsky

Email: matiz853@yandex.ru
Russian Federation, Saratov, Russia

A I Zavyalov

Saratov State Medical University named after V.I. Razumovsky

Email: ark.zavyalow@yandex.ru
Russian Federation, Saratov, Russia

A S Potapova

Yuri Gagarin State Technical University of Saratov

Email: matiz853@yandex.ru
Russian Federation, Saratov, Russia

References

  1. Russian statistical yearbook 2019. Federal state statistic cervice 2019. https://rosstat.gov.ru/storage/mediabank/Ejegodnik_2019.pdf (access date: 04.07.2021). (In Russ.)
  2. Balunov P.A., Khitrov A.N. Pharmacoeconomic aspects of the use of bronchodilators in the management of COPD: real clinical practice. Meditsinsky Sovet. 2018; (21): 96–104. (In Russ.) doi: 10.21518/2079-701X-2018-21-96-104.
  3. Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease COPD. (2020 Report). https://goldcopd.org/wp-content/uploads/2019/12/GOLD-2020-FINAL-ver1.2-03Dec19_WMV.pdf (access date: 04.07.2021).
  4. Kytikova O.Ju., Gvozdenko T.A., Antonyuk M.V. Modern aspects of prevalence of chronic bronchopulmonary diseases. Byulleten fiziologii i patologii dykhaniya. 2017; (64): 94–100. (In Russ.) doi: 10.12737/article_5936346fdfc1f3.32482903.
  5. Chazova I.E., Nevzorova V.A., Ambatiello L.G., Brodskaia T.A., Oshchepkova E.V., Belevskii A.S., Zhernakova J.V., Aisanov Z.R., Ovcharenko S.I., Chuchalin A.G. Clinical practice guidelines on the diagnosis and treatment of patients with arterial hypertension and chronic obstructive pulmonary disease. Sistemnye gipertenzii. 2020; 17 (3): 7–34. (In Russ.) doi: 10.26442/2075082X.2020.3.200294.
  6. Varmaghani M., Dehghani M., Heidari E., Sharifi F., Moghaddam S.S., Farzadfar F. Global prevalence of chronic obstructive pulmonary disease: systematic review and meta-analysis. East Mediterr. Health J. 2019; 25 (1): 47–57. doi: 10.26719/emhj.18.014.
  7. Adeloye D., Chua S., Lee C., Basquill C., Papana A., Theodoratou E., Nair H., Gasevic D., Sridhar D., Campbell H., Chan K.Y., Sheikh A., Rudan I.; Global Health Epidemiology Reference Group (GHERG). Global and regional estimates of COPD prevalence: Systematic review and meta-analysis. Global Health Epidemiology Reference Group (GHERG). J. Glob. Health. 2015; 5 (2): 020415. doi: 10.7189/jogh.05-020415.
  8. Federal clinical guidelines for the diagnosis and treatment of chronic obstructive pulmonary disease. M.: Russian Respiratory Society. 2013. https://mzur.ru/upload/iblock/aaf/KHOBL.pdf (access date: 03.07.2021). (In Russ.)
  9. Krasnova Y.N. Medical social expertise of patients with chronic obstructive pulmonary disease: the opinion of the clinician. Sibirskiy meditsinskiy zhurnal (Irkutsk). 2015; 132 (1): 128–132. (In Russ.)
  10. Postnikova L.B., Kostrov V.A., Boldina M.V., Zelyaeva N.V. The prevalence of chronic obstructive pulmonary disease in a large industrial center (Nizhny Novgorod). Pulmonologiya. 2011; (2): 5–8. (In Russ.) doi: 10.18093/0869-0189-2011-0-2-5-8.
  11. Nugmanova D., Feshchenko Y., Iashyna L., Gyrina O., Malynovska K., Mammadbayov E., Akhundova I., Nurkina N., Tariq L., Makarova J., Vasylyev A. The prevalence, burden and risk factors associated with chronic obstructive pulmonary disease in Commonwealth of Independent States (Ukraine, Kazakhstan and Azerbaijan): results of the CORE study. BMC Pulm. Med. 2018; 18: 26. doi: 10.1186/s12890-018-0589-5.
  12. Ovcharenko S.I., Ajsanov Z.R., Leshhenko I.V. Hronicheskaja obstruktivnaja bolezn' legkih. Rukovodstvo dlja praktikujushhih vrachej. (Chronic obstructive pulmonary disease. A guide for practicing physicians.) Moscow: GEOTAR-Media, 2016; 192 p. (In Russ.)
  13. Results of the GARD project: the number of patients with COPD and bronchial asthma can exceed official statistics. Meditsinskiy sovet. 2014; (16): 5. (In Russ.)
  14. Ford E.S., Murphy L.B., Khavjou O., Giles W.H., Holt J.B., Croft J.B. Total and state-specific medical and absenteeism costs of COPD among adults aged ≥18 years in the United States for 2010 and projections through 2020. Chest. 2015; 147 (1): 31–45. doi: 10.1378/chest.14-0972.
  15. Hattori K., Kida K. Management of older adults with COPD. Nihon. Rinsho. 2016; 74 (5): 858–863. PMID: 27254959.
  16. Kontsevaya A.V., Mukaneyeva D.K., Balanova Yu.A., Khudyakov M.B., Drapkina O.M. Economic burden of respiratory diseases and chronic obstructive pulmonary disease in Russian Federation, 2016. Pulmonologiya. 2019; 29 (2): 159–166. (In Russ.) doi: 10.18093/0869-0189-2019-29-2-159-166.
  17. Vjortkin A.L., Shpagina L.A. KhOBL. Rukovodstvo dlya prakticheskikh vrachey. (COPD. A guide for practical doctors.) M.: Izdatel'stvo “E”. 2018; 144 р. (In Russ.)
  18. The problem of pulmonary diseases in Russia: a round table resolution. https://vspru.ru/media/853321/4.pdf (access date: 04.07.2021). (In Russ.)
  19. Global Initiative for Chronic Obstructive Lung Di¬sease. Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Pulmonary Disease COPD. (2019 Report). https://goldcopd.org/wp-content/uploads/2018/11/GOLD-2019-v1.7-FINAL-14Nov2018-WMS.pdf (access date: 04.07.2021).
  20. Akramova E.G. Problems of diagnostics of komorbidny forms of the chronic obstructive pulmonary disease. Nauchnoe obozrenie. Meditsinskie nauki. 2016; (5): 5–22 (In Russ.)
  21. Statistical compendium 2016: statistical materials. M.: Ministry of Health of the Russian Federation. 2017. https://www.rosminzdrav.ru/ministry/61/22/stranitsa979/statisticheskie-i-informatsionnye-materialy/statisticheskiy-sbornik-2016-god (access date: 21.12.2020). (In Russ.)
  22. Günen H., Tarraf H., Nemati A., Ghobain M.Al., Mutairi S.Al., Bacha Z.A., Waterpipe tobacco smoking. Tuberk. Toraks. 2016; 64 (1): 94–96. doi: 10.5578/tt.13935.
  23. Reinikovaite V., Rodriguez I.E., Karoor V., Rau A., Trinh B.B., Deleyiannis F.W., Taraseviciene-Stewart L. The effects of electronic cigarette vapour on the lung: direct comparison to tobacco smoke. Eur. Respir. J. 2018; 51: 1701661. doi: 10.1183/13993003.01661-2017.
  24. Singh K.P., Lawyer G., Muthumalage T., Maremanda K.P., Khan N.A., McDonough S.R., Ye. D., McIntosh S., Rahman I. Systemic biomarkers in electronic cigarette users: implications for noninvasive assessment of vaping-associated pulmonary injuries. ERJ Open Res. 2019; 5 (4): 00182–2019. doi: 10.1183/23120541.00182-2019.
  25. Gudz' V.V., Gal'cov V.G., Isaev M.Ju., Dolich V.N., Komleva N.E. Tobacco smoking problem among young people, in Gigiena i sanitarija na strazhe zdorov'ja cheloveka. Materialy mezhregional'noj nauchno-prakticheskoj konferencii molodyh uchenyh i specialistov. (Hygiene and sanitation on guard of human health. Materials of the interregional scientific-practical conference of young scientists and specialists.) Saratov: FBUN Saratovskij NII SG Rospotrebnadzora. 2019. https://www.elibrary.ru/item.asp?id=41473837 (access date: 04.07.2021). (In Russ.)
  26. Vasil'eva O.S., Kuz'mina L.P., Kravchenko N.Yu. A role of molecular analysis for diagnosis and prevention of occupational lung diseases. Pulmonologiya. 2017; 27 (2): 198–205. (In Russ.) doi: 10.18093/0869-0189-2017-27-2-198-205.
  27. Alif S.M., Dharmage S.C., Bowatte G., Karahalios A., Benke G., Dennekamp M., Mehta A.J., Miedinger D., Künzli N., Probst-Hensch N., Matheson M.C. Occupational exposure and risk of chronic obstructive pulmonary disease: a systematic review and meta-analysis. Expert Rev. Respir. Med. 2016; 10 (8): 861–872. doi: 10.1080/17476348.2016.1190274.
  28. Würtz E.T., Schlünssen V., Malling T.H., Hansen J.G., Omland O. Occupational COPD among ¬Danish never-smokers: a population-based study. J. Occup. Environ. Med. 2015; 72 (6): 456–459. doi: 10.1136/oemed-2014-102589.
  29. López-Campos J.L., Tan W., Soriano J.B. Global burden of COPD. Respirology. 2016; 21 (1): 14–23. doi: 10.1111/resp.12660.
  30. Global and regional burden of chronic respiratory disease in 2016 arising from non-infectious airborne occupational exposures: a systematic analysis for the Glo-bal Burden of Disease Study 2016. J. Occup. Environ. Med. 2020; 77 (3): 142–150. doi: 10.1136/oemed-2019-106013.
  31. Professional'nye bolezni. Rukovodstvo dlya vrachey. (Occupational diseases. A guide for doctors.) Ed. by N.A. Mukhin, S.A. Babanov. M.: GEOTAR-Media. 2018; 576 p. (In Russ.)
  32. Sakolchik M.A., Gorblyansky Yu.Yu., Podmogilnaya K.V., Fedyakina V.V. Epidemiological features of occupational chronic obstructive lung disease. Meditsina truda i promyshlennaya ekologiya. 2018; (7): 51–55. (In Russ.) doi: 10.31089/1026-9428-2018-7-51-55.
  33. Bloemsma L.D., Hoek G., Smit L.A.M. Panel studies of air pollution in patients with COPD: Systematic review and meta-analysis. Environ. Res. 2016; 151: 458–468. doi: 10.1016/j.envres.2016.08.018.
  34. Márquez-Martín E., Soriano J.B., Rubio M.C., Lopez-Campos J.L.; 3E project. Differences in the use of spirometry between rural and urban primary care centers in Spain. Int. J. Chron. Obstruct. Pulmon. Dis. 2015; 10 (1): 1633–1639. doi: 10.2147/COPD.S86074.
  35. Gambarjan M.G., Kalinina A.M., Shal'nova S.A., Smirnova M.I., Deev A.D. Investigation of the epidemiological features of chronic respiratory diseases in relation to the region of residence in Russia. Profilakticheskaya meditsina. 2015; 18 (1): 14–20. (In Russ.) doi: 10.17116/profmed201518114-20.
  36. Silva G.E, Sherrill D.L., Guerra S., Barbee R.A. Asthma as a risk factor for COPD in a longitudinal study. Chest. 2004; 126 (1): 59–65. doi: 10.1378/chest.126.1.59.
  37. Stoller J.K., Aboussouan L.S. A review of α1-antitrypsin deficiency. Am. J. Respir. Crit. Care Med. 2012; 185 (3): 246–259. doi: 10.1164/rccm.201108-1428CI.
  38. Ding Z., Wang K., Li J., Tan Q., Tan W., Guo G. Association between glutathione S-transferase gene M1 and T1 polymorphisms and chronic obstructive pulmonary disease risk: A meta-analysis. Clin. Genet. 2018; 95 (1): 53–62. doi: 10.1111/cge.13373.
  39. Hunninghake G.M., Cho M.H., Tesfaigzi Y., Soto-Quiros M.E., Avila L., Lasky-Su J., Stidley C., Melén E., Söderhäll C., Hallberg J., Kull I., Kere J., Svartengren M., Pershagen G., Wickman M., Lange C., Demeo D.L., Hersh C.P., Klanderman B.J., Raby B.A., Sparrow D., Shapiro S.D., Silverman E.K., Litonjua A.A., Weiss S.T., Celedón J.C. MMP12, lung function, and COPD in high-risk populations. N. Engl. J. Med. 2009; 361 (27): 2599–2608. doi: 10.1056/NEJMoa0904006.
  40. Samsonova T.V., Luchkevich V.S., Samodova I.L., Logunov D.L. Quality of life features of patients with chronic lung disease and their dynamics in hospital treatment. Vestnik rossiyskoy voenno-meditsinskoy akademii. 2014; (1): 91–94. (In Russ.)
  41. Kosarev V.V., Babanov S.A. Occupational chronic obstructive pulmonary disease. RMZh. 2014; (5): 348–355. (In Russ.)
  42. Trubetskoy A.D. Analysis of motivation for acting subjects in diagnostics of occupational diseases. Gigiena i sanitariya. 2020; 99 (11): 1217–1221. (In Russ.) doi: 10.47470/0016-9900-2020-99-11-1217-1221.
  43. Vermylen J.H., Szmuilowicz E., Kalhan R. Palliative care in COPD: an unmet area for quality improvement. Int. J. Chron. Obstruct. Pulmon. Dis. 2015; 10: 1543–1551. doi: 10.2147/COPD.S74641.
  44. Order of the Ministry of Health of the Russian Federation No. 29n, issued at 28.01.2021 “On Approval of the Procedure for Conducting mandatory preliminary and periodic Medical examinations of Employees provided for in Part Four of Article 213 of the Labor Code of the Russian Federation, the list of medical contraindications to performing work with harmful and (or) dangerous Industrial factors, as well as work in which mandatory preliminary and periodic medical examinations are carried out”. (In Russ.)
  45. Babanov S.A., Averina O.M. COPD. Medical history. Consilium Medicum. 2012; 14 (3): 70–73. (In Russ.)
  46. Segal L.N., Martine F.J. Chronic obstructive pulmonary disease subpopulations and phenotyping. J. Allergy Clin. Immunol. 2018; 141 (6): 1961–1971. doi: 10.1016/j.jaci.2018.02.035.
  47. Veremchuk L.V., Mineeva E.E., Vitkina T.I. Choice of functional methods of study of the respiratory system at the assessment of the risk of the urban environment effect on patients with chronic obstructive pulmonary disease. Byulleten fiziologii i patologii dyhaniya. 2018; (68): 23–27. (In Russ.) doi: 10.12737/article_5b189048ed62b6.15603461.
  48. Savushkina O.I., Cherniak A.V. Bodipletizmografiya: theoretical and clinical aspects. Meditsinskiy alfavit. 2018; 2 (23): 13–17. (In Russ.)
  49. Sinopalnikov A.I., Romanovskikh A.G., Belotserkovskaya Yu.G. New possibilities of pharmacotherapy for chronic obstructive pulmonary disease. Meditsinskiy sovet. 2018; (15): 28–37. (In Russ.) doi: 10.21518/2079-701X-2018-15-28-37.
  50. Ledvanova T.Y., Barylnik Y.B., Filippova N.V., Deeva M.A., Vdovenko I.V. Features of consciousness and value orientations in patients with chronic lung disease. Mezhdunarodnyy zhurnal prikladnyk i fundamentalnykh issledovaniy. 2015; (10-4): 643–648. (In Russ.)
  51. Khaltaev N., Axelrod S. Chronic respiratory diseases global mortality trends, treatment guidelines, life style modifications, and air pollution: preliminary analysis. J. Thorac. Dis. 2019; 11 (6): 2643–2655. doi: 10.21037/jtd.2019.06.08.
  52. Fitzsimmons D.A., Thompson J., Bentley C.L., Mountain G.A. Comparison of patient perceptions of Telehealth-supported and specialist nursing interventions for early stage COPD: a qualitative study. BMC Health Services Research. 2016; 16 (1): 420. doi: 10.1186/s12913-016-1623-z.
  53. Mishlanov V.Yu., Chuchalin A.G., Chereshnev V.A., Shubin I.V., Nikitin A.E. New technologies in rehabilitation of patients with respiratory diseases. Telemonitoring and telerehabilitation. Prakticheskaya pulmonologiya. 2019; (3): 28–31. (In Russ.)

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

© 2021 Eco-Vector




This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies