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Pharmacological Modulation of Cognitivr Test Solution in Mice of Two Genotypes
- Authors: Perepelkina O.V.1, Poletaeva I.I.1
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Affiliations:
- Lomonossov Moscow State University
- Issue: Vol 518, No 1 (2024)
- Pages: 93-95
- Section: Articles
- URL: https://kazanmedjournal.ru/2686-7389/article/view/651405
- DOI: https://doi.org/10.31857/S2686738924050169
- ID: 651405
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Abstract
Mice of two strains selected for successful solution of “object permanence” test and for lack of such solution demonstrated the differential reaction to injections of two drugs. The injections of atomoxetine. which blocks the noradrenaline reuptake, and of ‘non-benzodiazepine” anxiolytic afobazol was different. The success of solutions increased in mice selected for this test “non-solution”: and decreased or was inefficient in mice, selected for successful solution of object permanence cognitive test.
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About the authors
O. V. Perepelkina
Lomonossov Moscow State University
Email: ingapoletaeva@mail.ru
Russian Federation, Moscow
I. I. Poletaeva
Lomonossov Moscow State University
Author for correspondence.
Email: ingapoletaeva@mail.ru
Russian Federation, Moscow
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