ACUTE TOXICITY OF THE MINERAL COMPLEX BASED ON NANOPOWDERS OF IRON, COPPER AND ZINC AFTER A SINGLE INTRAPERITONEAL INJECTION

Мұқаба

Дәйексөз келтіру

Толық мәтін

Аннотация

An injection form of the mineral complex consisting of a mixture of iron, zinc and copper nanopowders has been proposed. According to the results of studies the injection form of the drug based on metal nanopowders belongs to the V-VI class of practically non-toxic, relatively harmless drugs by Hodge and to the 5th class of toxicity in accordance with GOST 32644-2014. 

Авторлар туралы

E. Andreeva

N.I. Vavilov Saratov State Agrarian University.

Хат алмасуға жауапты Автор.
Email: fake@neicon.ru
410012, Saratov. Ресей

T. Rodionova

N.I. Vavilov Saratov State Agrarian University.

Email: fake@neicon.ru
410012, Saratov. Ресей

D. Gorbunov

Institute of Toxicology of the Federal Medical and Biological Agency.

Email: fake@neicon.ru
192019, Saint-Petersburg. Ресей

M. Marinicheva

N.I. Vavilov Saratov State Agrarian University.

Email: fake@neicon.ru
410012, Saratov. Ресей

Әдебиет тізімі

  1. Polyanskaya I.S. New classification of bioelements in bioelementology. Milk herald. 2014; 1: 34-41. (in Russian)
  2. Alyautdin R.N., Romanov B.K. Recommendations for the evaluation of the safety of drugs containing nanoparticles. Safety and risk of pharmacotherapy. 2015; 5: 10-21. (in Russian)
  3. Guidelines for conducting preclinical studies of drugs. Part one. Edited by Mironov A.N. - M .: Grief and K, 20- 944 p. (in Russian)
  4. GOST 32644-2014 Test methods for the effects of chemical products on the human body. Acute oral toxicity - method for determining the class of acute toxicity, 2015. (in Russian)
  5. Reznichenko L.S., Dybkova S.N., Doroshenko A.M., Chekmani I.S., Ulberg Z.R. Synthesis of iron nanoparticles and characterization of their biosafety. Bulletin of problems of biology and medicine. 2014; 3 (2): 319-323. (in Russian)
  6. Prozorovsky V.B. Statistical processing of pharmacological research results. Psychopharmacology and biological narcology. 207 (3): 2090-2120. (in Russian

Қосымша файлдар

Қосымша файлдар
Әрекет
1. JATS XML
Жүктеу

© Andreeva E.Y., Rodionova T.N., Gorbunov D.V., Marinicheva M.P., 2018


СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 81728 от 11 декабря 2013.