Synthesis of Principal Building Blocks of Amphidinolides of the G and H Families

Мұқаба

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

Based on the reactions of diastereoselective allylation of (R)-2,3-O-cyclohexylideneglyceraldehyde with methyl 3-(bromomethyl)but-3-enoate and its allylstannyl derivative, unsaturated lactones (6R)- and (6S)-6-[(2R)-1,4-dioxaspiro[4.5]dec-2-yl]-4-methyl-5,6-dihydro-2H-pyran-2-ones were synthesized. After highly diastereoselective reduction, these lactones found application in the implementation of a new retrosynthetic scheme for the preparation of С5–С14, С15–С19 and С20–С26 building blocks of amphidinolides of the G and H families.

Толық мәтін

Рұқсат жабық

Авторлар туралы

Irina Mineeva

Institute for Physical Chemical Problems of the Belarusian State University

Хат алмасуға жауапты Автор.
Email: i.mineyeva@yandex.ru
ORCID iD: 0000-0002-6422-1967
Белоруссия, 14, Leningradskaya St., Minsk, 220006

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