A Simple Method for the Synthesis of Pyrazolo[1,2-c]benzo-1,3,4-thiadiazepine Derivatives Based on Formaldehyde, Acrolein, and 2-Mercaptobenzoic Acid Hydrazide

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Resumo

Based on 2-mercaptobenzoic acid hydrazide and commercially available formaldehyde and acrolein, a two-step method for the synthesis of a previously unknown 1-hydroxy-2,3-dihydropyrazolo[1,2-c]benzo-1,3,4-thiadiazepin-11(5H)-one, as a compound with a targeted antitumor effect, as well as a promising bioactive co-ligand for obtaining of gold glyco-nanoparticles for the biomedical purposes was developed

Sobre autores

A. Ershov

Institute of Macromolecular Compounds of the Russian Academy of Sciences

Email: martynenkoff@gmail.com
ORCID ID: 0000-0002-2266-4380
Rússia, Bol′shoi prosp., 31, St. Petersburg, 199004

I. Lagoda

State Research Testing Institute of Military Medicine, Ministry of Defense of the Russian Federation

Email: martynenkoff@gmail.com
ORCID ID: 0000-0002-3906-2909
Rússia, Lesoparkovaya ul., 4, St. Petersburg, 195043

A. Batyrenko

State Research Testing Institute of Military Medicine, Ministry of Defense of the Russian Federation

Email: martynenkoff@gmail.com
ORCID ID: 0000-0001-9688-3650
Rússia, Lesoparkovaya ul., 4, St. Petersburg, 195043

A. Martynenkov

Institute of Macromolecular Compounds of the Russian Academy of Sciences

Autor responsável pela correspondência
Email: martynenkoff@gmail.com
ORCID ID: 0000-0002-0951-1451
Rússia, Bol′shoi prosp., 31, St. Petersburg, 199004

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