First finding of antibacterial activity in cestodes

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Abstract

The results of the study support the presence of antibacterial substances in the tissues and secretion products of cestodes Eubothrium rugosum and Triaenophorus nodulosus living in the intestines of fish. The growth of test strains Escherichia coli, Staphylococcus aureus, Shigella sonnei, Salmonella enteritidis, Micrococcus luteus, Pseudomonas aeruginosa was significantly reduced in a liquid medium containing the incubation medium of cestodes or extracts from their tissues. The study revealed a multidirectional effect of the cestode incubation medium, tegument fraction, and tissue extracts on bacterial growth, as well as features of the effect on the bacteria of different taxa. Shigella sonnei demonstrated the highest level of growth suppression due to the antibacterial effect of the incubation media and extracts from Eubothrium rugosum and Triaenophorus nodulosus tegument.

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About the authors

G. I. Izvekova

Papanin Institute for Biology of Inland Waters Russian Academy of Sciences

Author for correspondence.
Email: izvekova@ibiw.ru
Russian Federation, Borok, Nekouzskii raion, Yaroslavl oblast

E. S. Filonchikova

Ural Branch of the Russian Academy of Sciences

Email: izvekova@ibiw.ru

Institute for Cellular and Intracellular Symbiosis

Russian Federation, Orenburg

T. V. Frolova

Papanin Institute for Biology of Inland Waters Russian Academy of Sciences

Email: izvekova@ibiw.ru
Russian Federation, Borok, Nekouzskii raion, Yaroslavl oblast

A. O. Plotnikov

Ural Branch of the Russian Academy of Sciences

Email: izvekova@ibiw.ru

Institute for Cellular and Intracellular Symbiosis

Russian Federation, Orenburg

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2. Fig. 1. Density in the liquid medium of test cultures of bacteria Shigella sonnei (a), Staphylococcus aureus (b) and Pseudomonas aeruginosa (c) during incubation with different fractions of the cestode Eubothrium rugosum. I – control; II – cestode incubation medium; III – tegument fraction; IV – worm extract.

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3. Fig. 2. Density in the liquid medium of test cultures of bacteria Shigella sonnei (a), Pseudomonas aeruginosa (b), Micrococcus luteus (c) and Escherichia coli (d) during incubation with different fractions of the cestode Triaenophorus nodulosus. I – control; II – cestode incubation medium; III – tegument fraction; IV – worm extract.

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