Fourier transform IR spectroscopic study of gamma-irradiated papain

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Аннотация

In papain macromolecules irradiated with γ-rays, fragments with terminal primary amino groups are formed, which appear in FTIR spectra as a broad peak with a maximum at 3440 cm–1, as well as an intense absorption band centred at 1706 cm–1 as a result of valence vibrations of carbonyl groups. The intensity of the absorption bands of the radiolysis products increases linearly with the irradiation dose of papain. At the same time, with increasing irradiation dose, a marked weakening of the intensity of the maxima of the absorption peaks of the peptide bond is observed, which indicates radiation destruction of the main chain of papain.

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Авторлар туралы

S. Allayarov

Federal Research Center for Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences

Хат алмасуға жауапты Автор.
Email: sadush@icp.ac.ru
Ресей, Chernogolovka

T. Rudneva

Institute of microelectronics technology and high purity materials, Russian Academy of Sciences

Email: sadush@icp.ac.ru
Ресей, Chernogolovka

S. Demidov

Federal Research Center for Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences

Email: sadush@icp.ac.ru
Ресей, Chernogolovka

U. Allayarova

Federal Research Center for Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences

Email: sadush@icp.ac.ru
Ресей, Chernogolovka

S. Chekalina

Federal Research Center for Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences

Email: sadush@icp.ac.ru
Ресей, Chernogolovka

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