Kazan medical journalKazan medical journal0368-48142587-9359Eco-Vector9094510.17816/kazmj90945Research ArticleEffect of xymedone on the vasculothrombocytic hemostasis in patients with ischemic heart diseaseSolovievaI. Z.<p>Department of Therapy No. 2, Department of Clinical Laboratory Diagnostics</p>info@eco-vector.comIbragimovO. B.<p>Department of Therapy No. 2, Department of Clinical Laboratory Diagnostics</p>info@eco-vector.comStolpnerE. M.<p>Department of Therapy No. 2, Department of Clinical Laboratory Diagnostics</p>info@eco-vector.comEpiphanyV. F.<p>Department of Therapy No. 2, Department of Clinical Laboratory Diagnostics</p>info@eco-vector.comTsibulkinA. I.<p>Department of Therapy No. 2, Department of Clinical Laboratory Diagnostics, Head. - prof.</p>info@eco-vector.comAlkhanovaN. A.<p>Department of Therapy No. 2, Department of Clinical Laboratory Diagnostics</p>info@eco-vector.comValeevaI. K.<p>Department of Therapy No. 2, Department of Clinical Laboratory Diagnostics</p>info@eco-vector.comKondratievaM. B.<p>Department of Therapy No. 2, Department of Clinical Laboratory Diagnostics</p>info@eco-vector.comMinullinaI. R.<p>Department of Therapy No. 2, Department of Clinical Laboratory Diagnostics</p>info@eco-vector.comMotinaN. V.<p>Department of Therapy No. 2, Department of Clinical Laboratory Diagnostics</p>info@eco-vector.comKazan State Medical AcademyCentral Research Laboratory of Kazan State Medical University1501199677122252312202123122021Copyright © 1996, Eco-Vector1996<p>The effect of medicinal drugs regenerating the vascular endothelium, in particular, xymedone on the vas- culothrombocytic hemostasis is studied. It is stated that the drug in daily dose equal to 1,5g prescribed during one month does not influence essentially the clinical dynamics, functional characteristics, lipid metabolism, serum atherogenicity, and aggregational ability of thrombocytes in patients with stress stenocardia, however, promotes the regeneration of plasminogen tissue activator level and fibrinolytic potential of the vascular wall.</p>Kazan Medical archiveКазанский медицинский архив[Балуда В. И., Баркаган З.С., Гольдберг ЕД. и др. Лабораторные методы исследования системы гемостаза. — Томск, 1980.][Богоявленский В.Ф. Коррекции функции внешнего и внутреннего дыхания, свертываемости крови и микроциркуляции у больных атеросклерозом: Авторсф. дисс. докт. мед. наук. — Казань, 1970.][Валимухаметова ДА., Слабнов Ю.Д., Цибуль- кин А.П. Ксимедон.— Научный сборник материалов экспериментальных и клинических испытаний. — Казань, 1986.][Габбасов З.А., Попов Е.Г., Гаврилов Ю.И. и др.//Лабор. дело. — 1989. — № 10. — С.15 — 18.][Зубаиров Д.А/.//Казанский мед. ж. — 1994. — № 2. — С. 136 — 155.][Измайлов Г. А., Шафиков И.З., Эвранова Г.Б. ^др. Ксимедон.— Научный сборник материалов экспериментальных и клинических испытаний. — Казань, 1986.][Лабораторные методы исследования в клинике.— Справочник под ред. В.В.Меньшикова. — М., 1987.][Люсов В.А., Белоусов Ю.Б., Грачев А. И. и др //Кардиология. — 1973. — № 12. — С. 32 — 37.][Камбург Р.А., Ибрагимов О.Б., Кондратьева М.Б., Валеева И.Х.//Бюлл. экспер. биол. — 1993. — № 8. - С. 205- 208.][Методы исследования фибринолитической системы./ Под ред. Андреенко Г.В. — М., 1981.][Тертое В.В., Качаров А.Г., Орехов А.Н.// Кардиология. — 1989. — № 8. — С. 35—37.][Шалаев С.В., Межецкая И.А.// Кардиология. — 1993. — № 5. — С. 9 — 12.][Юнусов Р.В.//Казанский мед.ж. — 1977. — № 3. - С. 60 - 63.][Вот G. V.R.// J. Physiol. - 1962. - Р. 67 - 68.][Constantinides R. In: Platelets and the vessel wall — fibrin deposition/ Ed.G.Schettler. — Stuttgart 1970. - P. 94. ’][R.Kamburg, O. Ibragimov, A. Mironov //in XX Nordic Congress of Physiology and Pharmacology. The Panum Institute, University of Copenhagen, August 16-19, 1992. Acta Physiologica Scandinavica, 1992 — Vol. 146.- Suppl. 608. - P. 174.][R.Kamburg, L. Popova, O. Ibragimov // in 59 European Atherosclerosis Society congress. — Nice May 17-21, 1992. - P. 120.][Ross R. //New Engl. J. Med. — 1986. — Vol 314,- P. 489-500.]