Kazan medical journalKazan medical journal0368-48142587-9359Eco-Vector9080010.17816/kazmj90800Research ArticleWhooping cough vaccinationShelogurovaA.info@eco-vector.comChildren's Clinic of Saratov State University150619282465585632112202121122021Copyright © 1928, Eco-Vector1928<p>Since the discovery of Bordet and Gengou, a new therapeutic agent-vaccine-appears in the treatment of pertussis. The first attempts at vaccine therapy for the disease date back to 1913. Since then, various types of vaccines have been used to treat pertussis: A vaccine of pure cultures of Bordet and Gengou bacilli, a vaccine of pertussis bacteria with Influenza bacilli, a group vaccine consisting of various microbes isolated from the sputum of patients (this type of vaccine was used by Peterson and Smelli, who obtained little results from it); finally, in a period of doubt about the specificity of Bordet and Gengou, a vaccine prepared from the sputum of pertussis patients was used. Kraus (1916) and Savini (1922), who used such a vaccine, report good results of treatment with it. Most authors, however, have used a vaccine prepared from Bordet and Gengou bacilli.</p>Kazan Medical archiveКазанский медицинский архив