Kazan medical journalKazan medical journal0368-48142587-9359Eco-Vector9057010.17816/kazmj90570Review ArticlePrevention of radiation damageGilevA. V.<p>Department of Radiation Diagnostics and Therapy</p>info@eco-vector.comVolodinaG. I.<p>Head - Prof., Department of Radiation Diagnostics and Therapy</p>info@eco-vector.comClinical Cancer Center of the Ministry of Health of the Republic of TatarstanKazan Institute for Advanced Training of Doctors150919947553823831612202116122021Copyright © 1994, Eco-Vector1994<p>The development and implementation of precision methods for pre-radiation topodosimetric preparation has significantly reduced the frequency of radiation injuries. The use of the VDF and NSD factors made adjustments to the planning of bioequivalent radiation regimes. Despite this, radiation complications remain a frequent limiting factor in radiation therapy. Recent studies have shown that the development and formation of radiation damage seems to be a complex and diverse process, not all aspects of which have been sufficiently studied. In the overwhelming number of patients who have undergone radiation therapy, there is a decrease in immunity parameters [12]. In the development of radiation injuries, the infection of the radiation zone [17], the prevalence of the malignant process [4], and regional circulatory disorders [6] are of direct importance. The conditions that predispose to the occurrence of radiation damage are trauma and inflammation. The frequency of radiation damage increases with the use of various types of chemotherapy, especially in combination with radiation therapy and hyperthermia [10]. The listed factors, which determine the development of distant radiation damage, create a prerequisite for the development of measures that protect the healthy tissues surrounding the tumor [8].</p>Kazan Medical archiveКазанский медицинский архив[Володина Г.И., Гилев А.В. Тезисы докладов VIII Республиканской научно-практической конференции рентгенологов и радиологов Молдавской ССР. — Кишинев, 1989. — С. 183 — 184.][Воробьев Ю.И., Кузьмина Т.Б., Манцева Л.И. и др. // Мед. радиол. — 1992.—№ 2. — С. 16 — 19.][Зиганшина Л.Е., Студенцова И.Д„ Заиконникова И.В. и др. // Фармакол. и токсикол. — 1990.—№ 1.—С. 57 — 59.][Краевский Н.А. Очерки патологической анатомии лучевой болезни. — М., 1957.][Кузнецов С.В., Никитис Я.А., Конеченкова Н.Е. // Вестн. рентгенол. и радиол. — 1987.—№ 3.—С. 8 — 13.][Овруцкий Г.Д., Орлова Г.Д., Зарипова С.М. и др. Отчет для Фарм. комитета МЗ РСФСР. — М., 1987.][Соловьев М.М. Воспалительные заболевания челюстно-лицевой области и шеи. — М., 1985.][Студенцова И.А. Заиконникова И.В., Визель А.О. и др. // Лицензионторг информирует. — 1986.—№ 18.—С. 29 — 30.][Чернов В.Н. Лекарственные и диагностические средства, применяемые в онкологической практике. — М., 1982.][Эйду с Л.Х. Физико-химические основы радиобиологических процессов и защиты от излучения. — М., 1972.][Backstrom A., Jacobsson P.A., Littbrand В. // Acta radiol (Ther.). — Stockh., 1973. — Vol. 12.—P. 406.][Barker I., Flether G. // Int. J. Radiat., Oncol., Biol., Phys. — 1977.—Vol. 2.—P. 407 — 414.][Buschkc F., Galente M. // Radiol. — 1959.—Vol. 73.—P. 11—15.][Delouche G., Brunet M., Guerin P. et al. // Ann. Radiol. — 1970. — Vol. 3. — P. 793.][Djendjan R., Merland I. Superselective arteriography of the external carotid artery. — Berlin: Springer, 1978.][Eschwege F., Bensadoum P., Wibault P. et al. // Cancers cavum, Fibromes nasopharyngeus: 20 congr. — Soc. Fr. Carcinol. — cerv. — faciale.- — Paris. — 1988. — P. 81—88.][Esser E., Schumann I., Wannemacher M. // J. Maxillafac. Surg. — 1976. — Vol. 4. — P. 26—33.][Fabert G., Ficat S. // Rew. med. Toulausc. — 1979.—Vol. 15.—P. 807—817.][Simon R., Cherry, Carnochan P., Babich J.W. et al. // J. Nucl. Med. — 1990.—Vol. 31.—P. 1307—1315.]