Kazan medical journalKazan medical journal0368-48142587-9359Eco-Vector8979510.17816/kazmj89795Research ArticleFactors contributing to the development of progressive paralysisZaitsevA. A.info@eco-vector.com15081933298-96676700612202106122021Copyright © 2022, Eco-Vector2022<p>At present, progressive paralysis is looked at as late spirochetosis, as true syphilis of the brain; however, almost everyone admits that for the defeat of c. n. with. some additional conditions are needed for the manifestation of the activity of the spirochete in the nervous tissue. The 5% susceptibility of luetics to progressive paralysis makes researchers look for these conditions in the constitution (Kretschmer, Kalman, Roster, Shostakovichi others). A view was also expressed about the different nature of spirochetes, giving in some cases a picture of general syphilis, in other cases, a picture of neuro-lues. The neurotropic nature of the spirochete is advocated by Levaditi and Marie.</p>Kazan Medical archiveКазанский медицинский архив