Kazan medical journalKazan medical journal0368-48142587-9359Eco-Vector841710.17816/KMJ2018-260Review ArticlePathophysiologic aspects of the development of cognitive disorders in chronic heart failure in elderly patientsPokachalovaM Amarisanna85@mail.ruSilyutinaM Vmarisanna85@mail.ruVoronezh State Medical University named after N.N. Burdenko1504201899226026430032018Copyright © 2018, Pokachalova M.A., Silyutina M.V.2018<p>The present literature review presents current views on pathophysiologic aspects of the formation and progression of cognitive disorders in chronic heart failure in elderly patients. Advanced age itself is an important predictor of the development of cardiovascular, neurodegenerative and other diseases. Involutive changes of cardiovascular system are known to potentiate the development of chronic heart failure. Heart failure in older people usually develops gradually. Formation of the cognitive deficit in heart disease is associated with chronic cerebral ischemia as well as a cascade of neurochemical processes occurring in the brain, eventually forming a vicious circle. Often the symptoms of cerebral ischemia due to reduced stroke volume occur much earlier than congestion signs in other organs and systems. Chronic cerebral ischemia that occurs due to violation of cerebral hemodynamics, is associated with both extracerebral and intracerebral causes, which in turn contributes to the development of chronic brain hypoxia and aggravation of cognitive dysfunction. Thus, the features of the development and course of disease in people of older age groups indicate that in geriatric practice existing diagnostic schemes are not always applicable. 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