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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Kazan medical journal</journal-id><journal-title-group><journal-title xml:lang="en">Kazan medical journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Казанский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0368-4814</issn><issn publication-format="electronic">2587-9359</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">81480</article-id><article-id pub-id-type="doi">10.17816/kazmj81480</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Efficiency of tiklide in the treatment of patients with diabetes mellitus of the II type</article-title><trans-title-group xml:lang="ru"><trans-title>Эффективность тиклида при лечении больных сахарным диабетом II типа</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Altshuler</surname><given-names>M. Yu.</given-names></name><name xml:lang="ru"><surname>Альтшулер</surname><given-names>М. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Saratov State Medical University</institution></aff><aff><institution xml:lang="ru">Саратовский государственный медицинский университет</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="1997-06-15" publication-format="electronic"><day>15</day><month>06</month><year>1997</year></pub-date><volume>78</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>194</fpage><lpage>195</lpage><history><date date-type="received" iso-8601-date="2021-09-30"><day>30</day><month>09</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-09-30"><day>30</day><month>09</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 1997, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 1997, Эко-Вектор</copyright-statement><copyright-year>1997</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://kazanmedjournal.ru/kazanmedj/article/view/81480">https://kazanmedjournal.ru/kazanmedj/article/view/81480</self-uri><abstract xml:lang="en"><p>The influence of tiklide on hemostasis indices and clinical manifestations of diabetes microangiopathy in patients with diabetes mellitus of the II type is studied. A pronounced clinical effect is shown, after the course of treatment with tiklide the antithrombogenic potential of a vascular wall is in excess of that before the treatment.</p></abstract><trans-abstract xml:lang="ru"><p>Изучено влияние тиклида на показатели гемостаза и клинические проявления диабетической микроангиопатии у пациентов с сахарным диабетом II типа. Показан выраженный клинический эффект, после курса лечения тиклидом антитромбогенный потенциал сосудистой стенки превышает таковой до лечения.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Kazan Medical archive</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Казанский медицинский архив</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Балаболкин М.И., Морозова Т.П., Чачиашвили М.В., Балуда М.В.// Актуальные проблемы гемостаза в клинической практике. — М., 1987.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Ена Я.М., Сушка Е.А., Волковская Т.Г. и др.// Пробл. эндокринол. — 1991. — № 5. — С. 64-70.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Standi Е.// Diabet. Res. Clin. Pract. — 1988. — Vol. 4. - P. 11-14.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Vokovich T. 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