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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Kazan medical journal</journal-id><journal-title-group><journal-title xml:lang="en">Kazan medical journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Казанский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0368-4814</issn><issn publication-format="electronic">2587-9359</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">80715</article-id><article-id pub-id-type="doi">10.17816/kazmj80715</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The role of zinc deficiency in the pathogenesis of dermatoses</article-title><trans-title-group xml:lang="ru"><trans-title>Роль дефицита цинка в патогенезе дерматозов</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sergeev</surname><given-names>V. P.</given-names></name><name xml:lang="ru"><surname>Сергеев</surname><given-names>В. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Professor, Department of Dermatovenereology</p></bio><bio xml:lang="ru"><p>профессор, кафедра дерматовенерологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Andreeva</surname><given-names>V. N.</given-names></name><name xml:lang="ru"><surname>Андреева</surname><given-names>В. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Dermatovenereology</p></bio><bio xml:lang="ru"><p>кафедра дерматовенерологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Kazan State Institute for Advanced Training of Physicians named after V.I.Lenin</institution></aff><aff><institution xml:lang="ru">Казанский Государственный институт для усовершенствования врачей имени В. И. Ленина</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="1981-02-15" publication-format="electronic"><day>15</day><month>02</month><year>1981</year></pub-date><volume>62</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>42</fpage><lpage>45</lpage><history><date date-type="received" iso-8601-date="2021-09-21"><day>21</day><month>09</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-09-21"><day>21</day><month>09</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 1981, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 1981, Эко-Вектор</copyright-statement><copyright-year>1981</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://kazanmedjournal.ru/kazanmedj/article/view/80715">https://kazanmedjournal.ru/kazanmedj/article/view/80715</self-uri><abstract xml:lang="en"><p>The interest of dermatologists in the study of zinc metabolism arose after the appearance of the article by Todd et al. (1934), in which it was indicated that a lack of zinc in the diet in rats leads to hair loss. Tucker (1955) and Dell (1958) in experiments on pigs and chickens not only confirmed the role of zinc deficiency in the genesis of alopecia areata, but also drew attention to the development of parakeratosis and histological changes in the mucous membrane of the esophagus.</p></abstract><trans-abstract xml:lang="ru"><p>Интерес дерматологов к изучению обмена цинка возник после появления статья Тодда и соавт. (1934), в которой было указано, что недостаток цинка в пище у крыс приводит к выпадению волос. Тукер (1955) и Делл (1958) в опытах на свиньях и цыплятах не только подтвердили роль недостаточности цинка в генезе гнездного облысения, но и обратили внимание на развитие паракератоза и гистологических изменений в слизистой оболочке пищевода.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Kazan Medical archive</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Казанский медицинский архив</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Боциев М. М. Содержание железа и цинка в крови больных экземой и псориазом. В сб.: Тр. Северо-Осетинского мед. ин-та. Орджоникидзе, 1971</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Буряк Л. И., Руденко А. К. Гиг. и сан., 1976, 1</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Дубина Т. Л. О возрастных особенностях содержания цинка в крови человека. 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