Kazan medical journalKazan medical journal0368-48142587-9359Eco-Vector7964310.17816/kazmj79643Research ArticleTo the doctrine of keratodermia palmaris et plantaris symmetrica (Besnier)YasnitskyN. N.info@eco-vector.com150119221811321460609202106092021Copyright © 2021, Eco-Vector2021<p>Skin diseases characterized by anomalies of keratinization in the sense of hypertrophy of the stratum corneum were named by Lebert in 1864 keratosis (keratosis circumscripta et keratosis diffusa). Hebra in his textbook on skin diseases distinguishes between the following two forms: keratosis without simultaneous participation in the process of skin papillae (callositas, clavus, cornu cutaneum) and keratosis, accompanied by more or less pronounced resolution of the papillary layer (verruca, ichthyosis).</p>Kazan Medical archiveКазанский медицинский архив