Kazan medical journalKazan medical journal0368-48142587-9359Eco-Vector7093010.17816/kazmj70930MiscellaneousTwo cases of Sjogren-Larsson syndrome in the same familyKuzminI. K.info@eco-vector.comGubarR. P.info@eco-vector.comVasilevskayaV. V.info@eco-vector.com151219866764594592305202123052021Copyright © 1986, Kuzmin I.K., Gubar R.P., Vasilevskaya V.V.1986<p>Sjоgren-Larsson syndrome is a hereditary disorder detected in the first months of a child's life. It is characterized by varying degrees of oligophrenia combined with spastic diplegia and congenital universal ichthyosis, and sometimes epileptic seizures, retinitis pigmentosa in the macula, dwarfism or giant growth, genital hypoplasia and anemia. Inheritance type is autosomal recessive with high penetrance and variable expression.</p>Kazan Medical archiveКазанский медицинский архив