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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Kazan medical journal</journal-id><journal-title-group><journal-title xml:lang="en">Kazan medical journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Казанский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0368-4814</issn><issn publication-format="electronic">2587-9359</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">70542</article-id><article-id pub-id-type="doi">10.17816/kazmj70542</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Use of microcrystalline cellulose in the treatment of thyroid gland hyperplasia in children</article-title><trans-title-group xml:lang="ru"><trans-title>Применение микрокристаллической целлюлозы в лечении гиперплазии щитовидной железы у детей</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Grebneva</surname><given-names>O. P.</given-names></name><name xml:lang="ru"><surname>Гребнева</surname><given-names>О. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Endocrinology</p></bio><bio xml:lang="ru"><p>Кафедра эндокринологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Anchikova</surname><given-names>L. I.</given-names></name><name xml:lang="ru"><surname>Анчикова</surname><given-names>Л. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Professor, Head of the Department of Endocrinology</p></bio><bio xml:lang="ru"><p>Профессор, заведующий кафедрой эндокринологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Kazan State Medical Academy of Postgraduate Education</institution></aff><aff><institution xml:lang="ru">Казанская государственная медицинская академия последипломного образования</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="1999-11-15" publication-format="electronic"><day>15</day><month>11</month><year>1999</year></pub-date><volume>80</volume><issue>6</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>412</fpage><lpage>414</lpage><history><date date-type="received" iso-8601-date="2021-05-13"><day>13</day><month>05</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-05-13"><day>13</day><month>05</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 1999, Grebneva O.P., Anchikova L.I.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 1999, Гребнева О.П., Анчикова Л.И.</copyright-statement><copyright-year>1999</copyright-year><copyright-holder xml:lang="en">Grebneva O.P., Anchikova L.I.</copyright-holder><copyright-holder xml:lang="ru">Гребнева О.П., Анчикова Л.И.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://kazanmedjournal.ru/kazanmedj/article/view/70542">https://kazanmedjournal.ru/kazanmedj/article/view/70542</self-uri><abstract xml:lang="en"><p>The children living in Kazan were examined to estimate the state of thyroid gland. The level of iodine saturation of the organism was evaluated by the cerium — arsenite method. The discrepancy between the incidence of thyroid gland hyperplasia and the amount of urinary excretion of iodine was revealed. The general health state of the children under study, peculiarities of their diet, and drugs being taken at the moment were analyzed. Taking into account the great incidence of gastro-intestinal tract injuries and allergic manifestations, the use of enterosorbent — microcrystalline cellulose in the treatment of children with thyroid gland hyperplasia was suggested. Two types of changes of urinary excretion of iodine proving the participation of enterosorbents in the correction of iodine content in the organism were revealed in the course of the treatment.</p></abstract><trans-abstract xml:lang="ru"><p>Гиперплазия щитовидной железы, обусловленная недостаточностью йода в организме человека, в последние годы привлекает пристальное внимание исследователей как основная проблема охраны общественного здоровья во всех странах. По оценке ВОЗ и ЮНИСЕФ, более миллиарда жителей Земли имеют риск развития йоддефицитных заболеваний.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Kazan Medical archive</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Казанский медицинский архив</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Виноградов А.П. 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