Kazan medical journalKazan medical journalКазанский медицинский журнал0368-48142587-9359Eco-Vector69028010.17816/KMJ690280JPJKFJTheoretical and clinical medicineТеоретическая и клиническая медицинаResearch ArticleSecretory function of the salivary glands and the psychological factor: a randomized clinical studyСекреторная функция слюнных желёз и психологический фактор: рандомизированное клиническое исследованиеhttps://orcid.org/0000-0002-2851-01714263-8215ShchipskiyAlexander V.ЩипскийАлександр Васильевич
Russian Federation

MD, Dr. Sci. (Medicine), Professor

д-р мед. наук, профессор

Sialocenter@mail.ruhttps://orcid.org/0000-0002-0935-8936KalimatovaMarina M.КалиматоваМарина Магомедовна
Russian Federation

Graduate Student, Depart. of Maxillofacial Surgery and Traumatology

аспирант, каф. челюстно-лицевой хирургии и травматологии

dockalimatova@mail.ruhttps://orcid.org/0000-0002-8311-5529MukhinPavel N.МухинПавел Николаевич
Russian Federation

MD, Cand. Sci. (Medicine). Assistant Lecturer, Depart. of Maxillofacial Surgery and Traumatology

канд. мед. наук, ассистент, каф. челюстно-лицевой хирургии и травматологии

panistom@mail.ruRussian University of MedicineРоссийский университет медицины2601202608022026107148551009202517102025Copyright ©; 2026, Eco-VectorCopyright ©; 2026, Эко-Вектор2026Eco-VectorЭко-Векторhttps://eco-vector.com/for_authors.php#07https://kazanmedjournal.ru/kazanmedj/article/view/690280

BACKGROUND: It is widely believed that xerostomia may be caused by emotional tension, anxious anticipation, and stress.

AIM: This work aimed to investigate the influence of psychological factors on the secretory function of the parotid glands.

METHODS: A two-stage controlled longitudinal sialometry was performed in 75 patients with sialadenosis and sialadenitis accompanied by xerostomia. Saliva from the parotid ducts was collected simultaneously using a Lashley capsule and a polyethylene catheter. After one week, the collection methods were alternated. In 71 patients, psychological personality type was determined; salivary cortisol levels were measured in 51 cases before stage 1 and in 50 cases before stage 2 of the study. The secretory function of the parotid glands obtained using different saliva collection methods (Lashley capsule and polyethylene catheter), the distribution of introverts, ambiverts, and extroverts determined by questionnaire, and morning salivary cortisol levels measured at the INVITRO laboratory were compared during the controlled longitudinal sialometry. Statistical analysis was performed using methods of variational statistics. Arithmetic means and their standard errors were calculated (M ± m). Significance of differences was assessed using Student’s t-test. Differences were considered significant at p ≤ 0.05.

RESULTS: When assessed using the Lashley capsule, parotid gland secretory function (n = 75) was normal in 54.0% of cases, showed hyposalivation in 28.0% of cases, and asialia in 18.0% of cases. When using the catheter, the corresponding values were 39.3%, 42.0%, and 18.7%, respectively. Hyposalivation was detected notably more frequently when the catheter was used compared with the Lashley capsule (t = 2.5698). Among the patients (n = 71), introverts accounted for 53.5% (t = 8.0867; p = 0.001), ambiverts for 45.1% (t = 7.4103; p = 0.001), and extroverts for 1.4%. Salivary cortisol levels before sialometry were within the normal range in all cases (100.0%); no changes were observed between the two study stages (t = 1.1239; t = 1.1076).

CONCLUSION: Introverts and ambiverts are more predisposed to xerostomia than extroverts.

Обоснование. Существует мнение, что причиной ксеростомии могут являться волнение, тревожное ожидание и стресс.

Цель исследования. Изучить влияние психологического фактора на секреторную функцию околоушных желёз.

Методы. У 75 пациентов с сиаладенозом и сиаладенитом, сопровождавшимися ксеростомией, провели двухэтапную контролируемую динамическую сиалометрию. Для забора слюны из околоушных протоков одновременно использовали капсулу Лешли и полиэтиленовый катетер. Через неделю методы забора меняли местами. У 71 пациента определили психологический тип личности; в 51 случае перед 1-м этапом и в 50 случаях перед 2-м этапом исследования определяли уровень кортизола в слюне. Сравнивали показатели секреторной функции околоушных желёз, полученные различными методами забора слюны (капсулой Лешли и полиэтиленовым катетером); распределение интровертов, амбивертов и экстравертов, установленное с помощью анкетирования; уровни кортизола в утренней слюне, определённые в лаборатории INVITRO, в динамике контролируемой динамической сиалометрии. Статистическую обработку проводили с помощью методов вариационной статистики. Определяли средние арифметические величины и их ошибку (М ± m), значимость различий оценивали с использованием t-критерия Стьюдента. Различия считали значимыми при p ≤ 0,05.

Результаты. Секреторная функция околоушных желёз (n = 75), исследованная с использованием капсулы Лешли, в 54,0% случаев соответствовала норме, в 28,0% случаев характеризовалась гипосаливацией и в 18,0% случаев — асиалией. При использовании катетера соответствующие показатели составили 39,3%, 42,0% и 18,7%. При применении катетера гипосаливацию выявляли значимо чаще по сравнению с капсулой Лешли (t = 2,5698). Среди пациентов (n = 71) интроверты составили 53,5% (t = 8,0867; p = 0,001), амбиверты — 45,1% (t = 7,4103; p = 0,001), экстраверты — 1,4%. Уровни кортизола в слюне перед сиалометрией во всех случаях находились в пределах нормы (100,0%); динамика между этапами отсутствовала (t = 1,1239; t = 1,1076).

Заключение. Интроверты и амбиверты более предрасположены к возникновению ксеростомии по сравнению с экстравертами.

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