<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Kazan medical journal</journal-id><journal-title-group><journal-title xml:lang="en">Kazan medical journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Казанский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0368-4814</issn><issn publication-format="electronic">2587-9359</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">66724</article-id><article-id pub-id-type="doi">10.17816/kazmj66724</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Functional state of immune and endocrinic systems in children of first three months of life with active cytomegalovirus infection</article-title><trans-title-group xml:lang="ru"><trans-title>Функциональное состояние иммунной и эндокринной систем у детей первых трех месяцев жизни с активной цитомегаловирусной инфекцией</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ozhegov</surname><given-names>A. M.</given-names></name><name xml:lang="ru"><surname>Ожегов</surname><given-names>А. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Pediatrics and Neonatology</p></bio><bio xml:lang="ru"><p>Кафедра педиатрии и неонатологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Penkina</surname><given-names>N. I.</given-names></name><name xml:lang="ru"><surname>Пенкина</surname><given-names>Н. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Pediatrics and Neonatology</p></bio><bio xml:lang="ru"><p>Кафедра педиатрии и неонатологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Myakisheva</surname><given-names>L. S.</given-names></name><name xml:lang="ru"><surname>Мякишева</surname><given-names>Л. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>Профессор, заведующий кафедрой педиатрии и неонатологи</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Maltsev</surname><given-names>S. V.</given-names></name><name xml:lang="ru"><surname>Мальцев</surname><given-names>С. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Professor, Corresponding Member of ANT, Director</p></bio><bio xml:lang="ru"><p>Профессор, член-корреспондент АНТ, директор, Кафедра педиатрии и неонатологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Izhevsk State Medical Academy</institution></aff><aff><institution xml:lang="ru">Ижевская государственная медицинская академия</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Republican Center for the Protection of Family, Motherhood and Childhood Ministry of Health of the Republic of Tatarstan</institution></aff><aff><institution xml:lang="ru">Республиканский центр охраны семьи, материнства и детства М3 РТ</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Republican Center for the Protection of Family, Motherhood and Childhood Ministry of Health of the Republic of Tatarstan</institution></aff><aff><institution xml:lang="ru">Республиканский центр охраны семьи, материнства и детства М3 РТ Казань</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="1999-04-02" publication-format="electronic"><day>02</day><month>04</month><year>1999</year></pub-date><volume>80</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>204</fpage><lpage>207</lpage><history><date date-type="received" iso-8601-date="2021-04-29"><day>29</day><month>04</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-04-29"><day>29</day><month>04</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 1999, Ozhegov A.M., Penkina N.I., Myakisheva L.S., Maltsev S.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 1999, Ожегов А.М., Пенкина Н.И., Мякишева Л.С., Мальцев С.В.</copyright-statement><copyright-year>1999</copyright-year><copyright-holder xml:lang="en">Ozhegov A.M., Penkina N.I., Myakisheva L.S., Maltsev S.V.</copyright-holder><copyright-holder xml:lang="ru">Ожегов А.М., Пенкина Н.И., Мякишева Л.С., Мальцев С.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://kazanmedjournal.ru/kazanmedj/article/view/66724">https://kazanmedjournal.ru/kazanmedj/article/view/66724</self-uri><abstract xml:lang="en"><p>The state of immune and endocrinic systems and their relation in children of first three months of life with active cytomegalovirus infection is studied. Significant immunity disorders as cellular reaction dysbalance and humoral link activation are revealed in children with active congenital cytomegalovirus infection. The association of lymphocyte subpopulations with the disease gravity and terms of infecting a child is established. The low level of thyroidin hormone T<sub>3</sub> that is the disease gravity criterion is revealed in 1/3 of children.</p></abstract><trans-abstract xml:lang="ru"><p>Среди внутриутробных инфекций одно из ведущих мест занимает цитомегаловирусная инфекция (ЦМВИ). Цитомегалия относится к “оппортунистическим” инфекциям, клинические проявления которой становятся возможными лишь в условиях первичного или вторичного иммунодефицита. Исследования, посвященные изучению иммунного статуса у детей с ЦМВИ, малочисленны и неоднозначны[2, 3]. Противоречивость этих данных связана, возможно, с различной активностью ЦМВИ, сроками инфицирования, а также с состоянием эндокринной системы ребенка.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Kazan Medical archive</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Казанский медицинский архив</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Келина Т.И. Роль факторов предрасположения, иммунных и нейроэндокринных реакций в обосновании дифференцированной тактики оздоровления часто и длительно болеющих детей: Автореф. дисс. докт. мед. наук. — М., 1993.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Моргунов К.В., Вартанян Р.В., Кетиладзе Е.С. и др. // Вопр. охр. мат. — 1990. — № 6. — С. 32—34.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Непокульчицкая Н.В., Долгина Е.Н., Самсы- гина Г.А. и др. // Педиатрия. — 1994. — № 6. — С. 23-26.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Kftikaneni Р., Flavia М. et al. // Diagn. Immunol. — 1985.-Vol. З.-Р. 38-42.</mixed-citation></ref></ref-list></back></article>
