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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Kazan medical journal</journal-id><journal-title-group><journal-title xml:lang="en">Kazan medical journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Казанский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0368-4814</issn><issn publication-format="electronic">2587-9359</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">65175</article-id><article-id pub-id-type="doi">10.17816/kazmj65175</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">On antidiphtheria immunity in uninoculated inhabitants of tatarstan republic</article-title><trans-title-group xml:lang="ru"><trans-title>О противодифтерийном иммунитете у непривитых жителей Республики Татарстан</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shafeev</surname><given-names>M. S.</given-names></name><name xml:lang="ru"><surname>Шафеев</surname><given-names>М. Ш.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Associate Professor, Head of the Department of Epidemiology</p></bio><bio xml:lang="ru"><p>Доцент, заведующий кафедрой эпидемиологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zorina</surname><given-names>L. M.</given-names></name><name xml:lang="ru"><surname>Зорина</surname><given-names>Л. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Epidemiology</p></bio><bio xml:lang="ru"><p>Кафедра эпидемиологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kolpachikhin</surname><given-names>F. B.</given-names></name><name xml:lang="ru"><surname>Колпачихин</surname><given-names>Ф. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Epidemiology</p></bio><bio xml:lang="ru"><p>Кафедра эпидемиологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sadykova</surname><given-names>D. G.</given-names></name><name xml:lang="ru"><surname>Садыкова</surname><given-names>Д. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Epidemiology</p></bio><bio xml:lang="ru"><p>Кафедра эпидемиологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Yakupov</surname><given-names>I. F.</given-names></name><name xml:lang="ru"><surname>Якупов</surname><given-names>И. Ф.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Epidemiology</p></bio><bio xml:lang="ru"><p>Кафедра эпидемиологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ismagilova</surname><given-names>Z. M.</given-names></name><name xml:lang="ru"><surname>Исмагилова</surname><given-names>З. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Epidemiology</p></bio><bio xml:lang="ru"><p>Кафедра эпидемиологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Yamaleev</surname><given-names>R. R.</given-names></name><name xml:lang="ru"><surname>Ямалеев</surname><given-names>Р. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Epidemiology</p></bio><bio xml:lang="ru"><p>Кафедра эпидемиологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Galeev</surname><given-names>А. G.</given-names></name><name xml:lang="ru"><surname>Галеев</surname><given-names>А. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Epidemiology</p></bio><bio xml:lang="ru"><p>Кафедра эпидемиологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ibragimov</surname><given-names>А. H.</given-names></name><name xml:lang="ru"><surname>Ибрагимов</surname><given-names>А. Х.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Epidemiology</p></bio><bio xml:lang="ru"><p>Кафедра эпидемиологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zabirov</surname><given-names>H. G.</given-names></name><name xml:lang="ru"><surname>Забиров</surname><given-names>Х. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Epidemiology</p></bio><bio xml:lang="ru"><p>Кафедра эпидемиологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ryzhova</surname><given-names>E. F.</given-names></name><name xml:lang="ru"><surname>Рыжова</surname><given-names>Е. Ф.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Epidemiology</p></bio><bio xml:lang="ru"><p>Кафедра эпидемиологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Potashova</surname><given-names>А. M.</given-names></name><name xml:lang="ru"><surname>Поташова</surname><given-names>А. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Epidemiology</p></bio><bio xml:lang="ru"><p>Кафедра эпидемиологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Ministry of Health of the Republic of Tatarstan</institution></aff><aff><institution xml:lang="ru">Министерство здравоохранения Республики Татарстан</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Kazan State Medical University</institution></aff><aff><institution xml:lang="ru">Казанский государственный медицинский университет</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Center of the State Sanitary and Epidemiological Supervision of the Moscow Region</institution></aff><aff><institution xml:lang="ru">Центр Госсанэпиднадзора Московского района</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="1999-01-15" publication-format="electronic"><day>15</day><month>01</month><year>1999</year></pub-date><volume>80</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>49</fpage><lpage>52</lpage><history><date date-type="received" iso-8601-date="2021-04-18"><day>18</day><month>04</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-04-18"><day>18</day><month>04</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 1999, Shafeev M.S., Zorina L.M., Kolpachikhin F.B., Sadykova D.G., Yakupov I.F., Ismagilova Z.M., Yamaleev R.R., Galeev А.G., Ibragimov А.H., Zabirov H.G., Ryzhova E.F., Potashova А.M.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 1999, Шафеев М.Ш., Зорина Л.М., Колпачихин Ф.Б., Садыкова Д.Г., Якупов И.Ф., Исмагилова З.М., Ямалеев Р.Г., Галеев А.Г., Ибрагимов А.Х., Забиров Х.Г., Рыжова Е.Ф., Поташова А.М.</copyright-statement><copyright-year>1999</copyright-year><copyright-holder xml:lang="en">Shafeev M.S., Zorina L.M., Kolpachikhin F.B., Sadykova D.G., Yakupov I.F., Ismagilova Z.M., Yamaleev R.R., Galeev А.G., Ibragimov А.H., Zabirov H.G., Ryzhova E.F., Potashova А.M.</copyright-holder><copyright-holder xml:lang="ru">Шафеев М.Ш., Зорина Л.М., Колпачихин Ф.Б., Садыкова Д.Г., Якупов И.Ф., Исмагилова З.М., Ямалеев Р.Г., Галеев А.Г., Ибрагимов А.Х., Забиров Х.Г., Рыжова Е.Ф., Поташова А.М.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://kazanmedjournal.ru/kazanmedj/article/view/65175">https://kazanmedjournal.ru/kazanmedj/article/view/65175</self-uri><abstract xml:lang="en"><p>Tension of antidi phtheria immunity among uninoculated persons in various indicatory groups of population of Tatarstan Republic in the presence of epidemic process intensification is studied. It is revealed that in 44,5—76,5% of uninoculated inhabitants in various indicatory groups and classes of population the titers were lower than protective. Taking into account a large percent of unprotected persons and absence of financial and material possibilities of determining the immunity level before inoculation the practice of performing thrice-repeated inoculation of adults older than 30 is justified.</p></abstract><trans-abstract xml:lang="ru"><p>Дифтерия относится к числу заболеваний, имеющих повсеместное распространение. Массовая иммунизация дифтерийным анатоксином, начатая в 50-х годах, способствовала значительному снижению заболеваемости. Самая низкая заболеваемость дифтерией была зарегистрирована в 70-е годы (0,03%ооо). Было даже высказано мнение, что ликвидация дифтерии может и должна быть достигнута в Европе к 1990 г. [3], но начиная с 80-х годов наблюдался рост заболеваемости.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Kazan Medical archive</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Казанский медицинский архив</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Бекетов А.П., Бекетова Е.В. Материалы VII съезда Всероссийского общества эпидемиологов, микробиологов и паразитологов. — М., 1997.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Галазка А. Материалы совещания по эпидемии дифтерии в Европе (5—7 июля 1993 г.). — СПб, 1993.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Галазка А. Иммунологические основы иммунизации дифтерии: ВОЗ, Женева, 1993.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Иванова В.В., Швалко А.Д., Сиземов А.Н. и др. 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