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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Kazan medical journal</journal-id><journal-title-group><journal-title xml:lang="en">Kazan medical journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Казанский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0368-4814</issn><issn publication-format="electronic">2587-9359</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">64591</article-id><article-id pub-id-type="doi">10.17816/kazmj64591</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Chronic overdose of oral antidiabetic drugs</article-title><trans-title-group xml:lang="ru"><trans-title>Хроническая передозировка пероральных противодиабетических препаратов</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Talantov</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Талантов</surname><given-names>В. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kupriyanova-Ashina</surname><given-names>N. V.</given-names></name><name xml:lang="ru"><surname>Куприянова-Ашина</surname><given-names>Н. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Kazan Order of the Red Banner of Labor Medical Institute named after S.V. Kypashov</institution></aff><aff><institution xml:lang="ru">Казанский орден Трудового Красного Знамени медицинского института имени С. В. Kypaшова</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="1993-02-15" publication-format="electronic"><day>15</day><month>02</month><year>1993</year></pub-date><volume>74</volume><issue>1</issue><issue-title xml:lang="ru"/><fpage>12</fpage><lpage>13</lpage><history><date date-type="received" iso-8601-date="2021-04-03"><day>03</day><month>04</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-04-03"><day>03</day><month>04</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 1993, Talantov V.V., Kupriyanova-Ashina N.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 1993, Талантов В.В., Куприянова-Ашина Н.В.</copyright-statement><copyright-year>1993</copyright-year><copyright-holder xml:lang="en">Talantov V.V., Kupriyanova-Ashina N.V.</copyright-holder><copyright-holder xml:lang="ru">Талантов В.В., Куприянова-Ашина Н.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="1996-02-15"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://kazanmedjournal.ru/kazanmedj/article/view/64591">https://kazanmedjournal.ru/kazanmedj/article/view/64591</self-uri><abstract xml:lang="en"><p>The introduction of new drugs into medical practice is accompanied by the need to solve such a problem as the correct choice of the drug, the identification of its toxic manifestations and side effects. Of practical importance is the syndrome of chronic insulin overdose (CSI) - Samoji syndrome, which is characterized by paradoxical hyperglycemia in response to an increase in the dose of insulin.</p></abstract><trans-abstract xml:lang="ru"><p>Внедрение в медицинскую практику новых лекарственных средств сопровождается одновременно необходимостью решения такой проблемы, как правильность выбора препарата, выявление его токсических проявлений и побочных эффектов. Практическое значение имеет синдром хронической передозировки инсулина (СХПИ) — синдром Самоджи, который характеризуется парадоксальной гипергликемией в ответ на увеличение дозы инсулина.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Kazan Medical archive</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Казанский медицинский архив</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list/></back></article>
