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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Kazan medical journal</journal-id><journal-title-group><journal-title xml:lang="en">Kazan medical journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Казанский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0368-4814</issn><issn publication-format="electronic">2587-9359</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">64590</article-id><article-id pub-id-type="doi">10.17816/kazmj64590</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Dimephosphone — vasoactive drug for normalization of nervous system function</article-title><trans-title-group xml:lang="ru"><trans-title>Димефосфон — вазоактивное средство для нормализации функции нервной системы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Khafizyaiiova</surname><given-names>R. Kh.</given-names></name><name xml:lang="ru"><surname>Хафизьянова</surname><given-names>Р. Х.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Studentsova</surname><given-names>I. A.</given-names></name><name xml:lang="ru"><surname>Студенцова</surname><given-names>И. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Danilov</surname><given-names>V. I.</given-names></name><name xml:lang="ru"><surname>Данилов</surname><given-names>В. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mokrinskaya</surname><given-names>I. S.</given-names></name><name xml:lang="ru"><surname>Мокринская</surname><given-names>И. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Garaev</surname><given-names>R. A.</given-names></name><name xml:lang="ru"><surname>Гараев</surname><given-names>Р. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gorozhanin</surname><given-names>A. B.</given-names></name><name xml:lang="ru"><surname>Горожанин</surname><given-names>А. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vizel</surname><given-names>A. O.</given-names></name><name xml:lang="ru"><surname>Визель</surname><given-names>А. О.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Masliiikin</surname><given-names>A. A.</given-names></name><name xml:lang="ru"><surname>Муслинкин</surname><given-names>А. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Kazan Order of the Red Banner of Labor of the Medical Institute named after S.V. Kuratov</institution></aff><aff><institution xml:lang="ru">Казанский орден Трудового Красного Знамени медицинского института имени С. В. Куратова</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">I.E. Arbuzov Institute of Physical Chemistry, KSC RAS</institution></aff><aff><institution xml:lang="ru">ИОФХ имени А. Е. Арбузова КНЦ РАН</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="1993-02-15" publication-format="electronic"><day>15</day><month>02</month><year>1993</year></pub-date><volume>74</volume><issue>1</issue><issue-title xml:lang="ru"/><fpage>8</fpage><lpage>12</lpage><history><date date-type="received" iso-8601-date="2021-04-03"><day>03</day><month>04</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-04-03"><day>03</day><month>04</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 1993, Khafizyaiiova R.K., Studentsova I.A., Danilov V.I., Mokrinskaya I.S., Garaev R.A., Gorozhanin A.B., Vizel A.O., Masliiikin A.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 1993, Хафизьянова Р.Х., Студенцова И.А., Данилов В.И., Мокринская И.С., Гараев Р.А., Горожанин А.Б., Визель А.О., Муслинкин А.А.</copyright-statement><copyright-year>1993</copyright-year><copyright-holder xml:lang="en">Khafizyaiiova R.K., Studentsova I.A., Danilov V.I., Mokrinskaya I.S., Garaev R.A., Gorozhanin A.B., Vizel A.O., Masliiikin A.A.</copyright-holder><copyright-holder xml:lang="ru">Хафизьянова Р.Х., Студенцова И.А., Данилов В.И., Мокринская И.С., Гараев Р.А., Горожанин А.Б., Визель А.О., Муслинкин А.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="1996-02-15"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://kazanmedjournal.ru/kazanmedj/article/view/64590">https://kazanmedjournal.ru/kazanmedj/article/view/64590</self-uri><abstract xml:lang="en"><p>An experimental study of dimephpsphone, using different models of the disorders of cerebrum and cerebral circulation functions, reveals cerebroprotcctive properties and normalizing type of the effect on the regulating mechanisms of cerebral circulation. Clinical tests indicate the efficacy of the drug in different central nervous system diseases in neurological and neurosurgical clinics.</p></abstract><trans-abstract xml:lang="ru"><p>Углубленное экспериментально-клиническое исследование димефосфона позволило дополнительно выявить его ценные свойства, что явилось основанием для разрешения клинического применения этого препарата по новым показаниям в качестве вазоактивного средства для нормализации функции нервной системы.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Kazan Medical archive</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Казанский медицинский архив</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Данилов В. И. Физиология, патофизиология и фармакология мозгового кровообращения.— Тез. докл.——Тбилиси, 1988.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Хафизьянова Р, X., Данилов В. И., Шульман X. М. и др. 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