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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Kazan medical journal</journal-id><journal-title-group><journal-title xml:lang="en">Kazan medical journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Казанский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0368-4814</issn><issn publication-format="electronic">2587-9359</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">64576</article-id><article-id pub-id-type="doi">10.17816/kazmj64576</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Acute drug allergy in large industrial city</article-title><trans-title-group xml:lang="ru"><trans-title>Анализ случаев острой лекарственной аллергии по данным специализированного отделения</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Reshetnikova</surname><given-names>I. D.</given-names></name><name xml:lang="ru"><surname>Решетникова</surname><given-names>И. Д.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Allergology, Department of Allergology </p> <p> </p><p> </p> </bio><bio xml:lang="ru"><p>Кафедра аллергологии, отделение аллергологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Voitsekhovich</surname><given-names>G. S.</given-names></name><name xml:lang="ru"><surname>Войцехович</surname><given-names>Г. С</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Allergology, Department of Allergology </p> <p> </p><p> </p> </bio><bio xml:lang="ru"><p>Кафедра аллергологии, отделение аллергологии </p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Khramov</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Храмов</surname><given-names>В. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Allergology, Department of Allergology </p> <p> </p><p> </p> </bio><bio xml:lang="ru"><p>Кафедра аллергологии, отделение аллергологии </p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Makarova</surname><given-names>L. V.</given-names></name><name xml:lang="ru"><surname>Макарова</surname><given-names>Л. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Allergology, Department of Allergology</p> <p> </p><p> </p> </bio><bio xml:lang="ru"><p>Кафедра аллергологии, отделение аллергологии </p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Fassakhov</surname><given-names>P. S.</given-names></name><name xml:lang="ru"><surname>Фассахов</surname><given-names>P. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Allergology, Department of Allergology</p> <p> </p><p> </p> </bio><bio xml:lang="ru"><p>Кафедра аллергологии, отделение аллергологии </p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Kazan State Medical Academy of Postgraduate Education</institution></aff><aff><institution xml:lang="ru">Казанская государственная медицинская академия последипломного образования</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">City Clinical Hospital No. 7</institution></aff><aff><institution xml:lang="ru">Городская клиническая больница № 7</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="1998-09-14" publication-format="electronic"><day>14</day><month>09</month><year>1998</year></pub-date><volume>79</volume><issue>5</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>359</fpage><lpage>362</lpage><history><date date-type="received" iso-8601-date="2021-04-03"><day>03</day><month>04</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-04-03"><day>03</day><month>04</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 1998, Reshetnikova I.D., Voitsekhovich G.S., Khramov V.V., Makarova L.V., Fassakhov P.S.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 1998, Решетникова И.Д., Войцехович Г.С., Храмов В.В., Макарова Л.В., Фассахов P.С.</copyright-statement><copyright-year>1998</copyright-year><copyright-holder xml:lang="en">Reshetnikova I.D., Voitsekhovich G.S., Khramov V.V., Makarova L.V., Fassakhov P.S.</copyright-holder><copyright-holder xml:lang="ru">Решетникова И.Д., Войцехович Г.С., Храмов В.В., Макарова Л.В., Фассахов P.С.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://kazanmedjournal.ru/kazanmedj/article/view/64576">https://kazanmedjournal.ru/kazanmedj/article/view/64576</self-uri><abstract xml:lang="en"><p>The causes of drug allergy development are considered. The case records of patients entering the allergologie department of the city hospital № 7 for 5 years are analyzed. The tendency to more frequent anaphylactic shock cases as the gravest variety of drug allergy is noted. The necessity of anaphylactic shock prevention measures is stressed in which the most important ones are the detailed collection of allergologie anamnesis, the account of possible crossed reactions between drugs.</p></abstract><trans-abstract xml:lang="ru"><p>Учащению случаев лекарственной аллергии способствуют необоснованное назначение лекарственных препаратов, полипрагмазия, недооценка фармакологического и аллергологического анамнеза. Лекарственная аллергия (ЛА) — побочное действие лекарств, в основе которого лежат специфические иммунологические механизмы, обусловливающие повышенную чувствительность к лекарственному препарату.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Kazan Medical archive</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Казанский медицинский архив</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Адо А.Д. Частная аллергология. — М., 1976.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Бережная Н.М., Бобкова Л.П., Петровская И.А., Ялкут С.И. Аллергология. Словарь-справочник. — Клев, 1986.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Горячкина Л.А., Поспелова Р.А, Фролова М.К., Храмцова Н.Н. // Тер. арх. — 1985. — № 2. — С. 138—144.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Лопатин А.С. 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